Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2083721..2083866 Replicon chromosome
Accession NZ_CP100715
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain R17.5474

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2083761..2083864 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2083721..2083866 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL730_RS10205 2080147..2080845 - 699 WP_000944282.1 exodeoxyribonuclease X -
NL730_RS10210 2080869..2081525 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
NL730_RS10215 2081633..2081863 - 231 WP_000856224.1 DNA polymerase III subunit theta -
NL730_RS10220 2082001..2082375 + 375 WP_000168393.1 CopC domain-containing protein YobA -
NL730_RS10225 2082376..2083251 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
NL730_RS10230 2083268..2083621 + 354 WP_000722368.1 YebY family protein -
- 2083721..2083866 - 146 - - Antitoxin
- 2083761..2083864 + 104 - - Toxin
NL730_RS10235 2083995..2084918 - 924 Protein_2002 tyrosine-type recombinase/integrase -
NL730_RS10240 2085182..2085643 - 462 Protein_2003 DNA breaking-rejoining protein -
NL730_RS10245 2085632..2085823 + 192 Protein_2004 glycoside hydrolase family 19 protein -
NL730_RS10250 2085877..2086410 + 534 WP_001050882.1 DUF2514 domain-containing protein -
NL730_RS10255 2086667..2086834 - 168 WP_000789530.1 lytic enzyme -
NL730_RS10260 2086899..2087087 - 189 WP_001521334.1 hypothetical protein -
NL730_RS10265 2087142..2087402 + 261 Protein_2008 DUF1441 family protein -
NL730_RS10270 2087404..2087619 + 216 Protein_2009 shikimate transporter -
NL730_RS10275 2087617..2087961 + 345 Protein_2010 macro domain-containing protein -
NL730_RS10280 2087971..2088441 + 471 Protein_2011 tail fiber assembly protein -
NL730_RS10285 2088538..2088738 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2078061..2103452 25391
inside Prophage - sopE2 2076742..2108723 31981


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251179 NZ_CP100715:2083761-2083864 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT251179 NZ_CP100715:c2083866-2083721 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References