Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2092278..2092423 Replicon chromosome
Accession NZ_CP100707
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain R18.0409

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2092318..2092421 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2092278..2092423 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL735_RS10270 2088704..2089402 - 699 WP_000944282.1 exodeoxyribonuclease X -
NL735_RS10275 2089426..2090082 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
NL735_RS10280 2090190..2090420 - 231 WP_000856224.1 DNA polymerase III subunit theta -
NL735_RS10285 2090558..2090932 + 375 WP_000168393.1 CopC domain-containing protein YobA -
NL735_RS10290 2090933..2091808 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
NL735_RS10295 2091825..2092178 + 354 WP_000722368.1 YebY family protein -
- 2092278..2092423 - 146 - - Antitoxin
- 2092318..2092421 + 104 - - Toxin
NL735_RS10300 2092552..2093475 - 924 Protein_2015 tyrosine-type recombinase/integrase -
NL735_RS10305 2093739..2094200 - 462 Protein_2016 DNA breaking-rejoining protein -
NL735_RS10310 2094189..2094380 + 192 Protein_2017 glycoside hydrolase family 19 protein -
NL735_RS10315 2094434..2094967 + 534 WP_001050882.1 DUF2514 domain-containing protein -
NL735_RS10320 2095224..2095391 - 168 WP_000789530.1 lytic enzyme -
NL735_RS10325 2095456..2095644 - 189 WP_001521334.1 hypothetical protein -
NL735_RS10330 2095699..2095959 + 261 Protein_2021 DUF1441 family protein -
NL735_RS10335 2095961..2096176 + 216 Protein_2022 shikimate transporter -
NL735_RS10340 2096174..2096518 + 345 Protein_2023 macro domain-containing protein -
NL735_RS10345 2096528..2096998 + 471 Protein_2024 tail fiber assembly protein -
NL735_RS10350 2097095..2097295 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2086618..2124935 38317


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T251134 NZ_CP100707:2092318-2092421 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT251134 NZ_CP100707:c2092423-2092278 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References