Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2143795..2143940 Replicon chromosome
Accession NZ_CP047550
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10057

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2143835..2143938 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2143795..2143940 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXN07_RS10465 2140221..2140919 - 699 WP_000944282.1 exodeoxyribonuclease X -
DXN07_RS10470 2140943..2141599 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
DXN07_RS10475 2141707..2141937 - 231 WP_000856224.1 DNA polymerase III subunit theta -
DXN07_RS10480 2142075..2142449 + 375 WP_000168393.1 CopC domain-containing protein YobA -
DXN07_RS10485 2142450..2143325 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
DXN07_RS10490 2143342..2143695 + 354 WP_000722368.1 YebY family protein -
- 2143795..2143940 - 146 - - Antitoxin
- 2143835..2143938 + 104 - - Toxin
DXN07_RS10495 2144069..2144992 - 924 Protein_2058 tyrosine-type recombinase/integrase -
DXN07_RS10500 2145256..2145717 - 462 Protein_2059 DNA breaking-rejoining protein -
DXN07_RS10505 2145706..2145897 + 192 Protein_2060 glycoside hydrolase family 19 protein -
DXN07_RS10510 2145951..2146484 + 534 WP_001050882.1 DUF2514 domain-containing protein -
DXN07_RS10515 2146741..2146908 - 168 WP_000789530.1 lytic enzyme -
DXN07_RS10520 2146973..2147161 - 189 WP_001521334.1 hypothetical protein -
DXN07_RS10525 2147216..2147476 + 261 Protein_2064 DUF1441 family protein -
DXN07_RS10530 2147691..2148035 + 345 Protein_2065 macro domain-containing protein -
DXN07_RS10535 2148045..2148515 + 471 Protein_2066 tail fiber assembly protein -
DXN07_RS10540 2148612..2148812 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2140221..2168797 28576


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T146643 NZ_CP047550:2143835-2143938 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT146643 NZ_CP047550:c2143940-2143795 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References