MGE detailed information
MGE type: Conjugative plasmid MGE length: 125802 bp
Accession: NZ_LR890199 Location: 1..125802 Organism: Escherichia coli isolate MINF_1D-sc-2280456 Replicon: plasmid 2
Accession: NZ_LR890199 Location: 1..125802 Organism: Escherichia coli isolate MINF_1D-sc-2280456 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMV89_RS24240 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| JMV89_RS24245 () | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| JMV89_RS24250 () | 2124..2306 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| JMV89_RS24255 () | 2649..2956 | - | 308 | Protein_3 | type II toxin-antitoxin system ParD family antitoxin | - |
| JMV89_RS24260 () | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| JMV89_RS24265 () | 4651..4779 | + | 129 | Protein_5 | IS481 family transposase | - |
| JMV89_RS24270 () | 4814..5107 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| JMV89_RS24275 () | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| JMV89_RS24280 () | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| JMV89_RS24285 () | 6377..7129 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| JMV89_RS24290 () | 7175..8140 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| JMV89_RS24295 () | 8173..8553 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| JMV89_RS24300 () | 8578..9468 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| JMV89_RS24305 () | 9701..9895 | - | 195 | WP_000796505.1 | hypothetical protein | - |
| JMV89_RS24310 () | 9869..10309 | + | 441 | Protein_14 | zinc-binding dehydrogenase | - |
| JMV89_RS24315 () | 10440..11318 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| JMV89_RS24320 () | 11308..12195 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| JMV89_RS24325 () | 12206..13030 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| JMV89_RS24330 () | 13036..14109 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| JMV89_RS24335 () | 14102..15412 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| JMV89_RS24340 () | 15471..15779 | - | 309 | Protein_20 | IS4 family transposase ISEc13 | Transposase |
| JMV89_RS24345 () | 15856..16089 | - | 234 | Protein_21 | Tn3 family transposase ISPsy39 | Transposase |
| JMV89_RS24350 () | 16111..17307 | - | 1197 | Protein_22 | IS3 family transposase | - |
| JMV89_RS24355 () | 17332..18036 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| JMV89_RS24360 () | 18094..18624 | - | 531 | Protein_24 | histidine-type phosphatase | - |
| JMV89_RS24365 () | 18746..19231 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| JMV89_RS24370 () | 19256..19741 | - | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| JMV89_RS24375 () | 19728..20423 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| JMV89_RS24380 () | 20428..21558 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| JMV89_RS24385 () | 21548..22831 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| JMV89_RS24390 () | 22834..24213 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| JMV89_RS24395 () | 24317..24844 | - | 528 | WP_000178050.1 | iron transporter | - |
| JMV89_RS24400 () | 24885..26771 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| JMV89_RS24405 () | 27118..27933 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| JMV89_RS24410 () | 28116..28622 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| JMV89_RS24415 () | 28612..28770 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| JMV89_RS24420 () | 28920..29033 | - | 114 | Protein_36 | IS6 family transposase | - |
| JMV89_RS24425 () | 29233..29930 | + | 698 | Protein_37 | IS1 family transposase IS1R | Transposase |
| JMV89_RS24430 () | 30089..30682 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| JMV89_RS24435 () | 30795..32000 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| JMV89_RS24440 () | 32082..32705 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| JMV89_RS24445 () | 32683..33369 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| JMV89_RS24450 () | 33377..33763 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| JMV89_RS24455 () | 33756..33965 | - | 210 | WP_071992733.1 | hypothetical protein | - |
| JMV89_RS24460 () | 34030..34734 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JMV89_RS24465 () | 34881..35117 | + | 237 | Protein_45 | IS3 family transposase IS1133 | Transposase |
| JMV89_RS24470 () | 35305..36567 | + | 1263 | WP_032153699.1 | IS1380 family transposase ISEcp1 | Transposase |
| JMV89_RS24475 () | 36823..37698 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| JMV89_RS24480 () | 37745..38077 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| JMV89_RS24485 () | 38091..40334 | + | 2244 | Protein_49 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JMV89_RS24490 () | 40399..41103 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| JMV89_RS24495 () | 41169..41714 | + | 546 | Protein_51 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JMV89_RS24500 () | 41750..42165 | - | 416 | Protein_52 | IS1 family transposase | - |
| JMV89_RS24505 () | 42414..42815 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JMV89_RS24510 () | 42748..43005 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JMV89_RS24515 () | 43098..43751 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JMV89_RS24520 () | 44691..45548 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| JMV89_RS24525 () | 45541..45615 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| JMV89_RS24530 () | 45612..45746 | - | 135 | Protein_58 | protein CopA/IncA | - |
| JMV89_RS24535 () | 45852..46004 | - | 153 | WP_072258247.1 | replication protein A | - |
| JMV89_RS24540 () | 46085..47107 | + | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| JMV89_RS24545 () | 47104..47886 | + | 783 | WP_001317493.1 | IS21 family transposase IS100kyp | Transposase |
| JMV89_RS24550 () | 47955..48065 | - | 111 | Protein_62 | replication protein | - |
| JMV89_RS24555 () | 48362..48496 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 48541..48601 | + | 61 | NuclAT_2 | - | - |
| - () | 48541..48601 | + | 61 | NuclAT_2 | - | - |
| - () | 48541..48601 | + | 61 | NuclAT_2 | - | - |
| - () | 48541..48601 | + | 61 | NuclAT_2 | - | - |
| JMV89_RS24560 () | 48568..48854 | - | 287 | Protein_64 | DUF2726 domain-containing protein | - |
| JMV89_RS24565 () | 49367..49579 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| JMV89_RS24570 () | 49710..50270 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| JMV89_RS24575 () | 50325..51071 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| JMV89_RS24580 () | 51091..56361 | - | 5271 | WP_032153768.1 | Multifunctional conjugation protein TraI | Relaxase |
| JMV89_RS24585 () | 56361..58550 | - | 2190 | WP_024946705.1 | type IV conjugative transfer system coupling protein TraD | - |
| JMV89_RS24590 () | 58547..59326 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| JMV89_RS24595 () | 59529..60260 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| JMV89_RS24600 () | 60292..60789 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| JMV89_RS24605 () | 60808..63627 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JMV89_RS24610 () | 63624..64997 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| JMV89_RS24615 () | 64984..65409 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| JMV89_RS24620 () | 65357..65704 | - | 348 | WP_011666494.1 | P-type conjugative transfer protein TrbJ | - |
| JMV89_RS24625 () | 65634..66179 | - | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JMV89_RS24630 () | 66166..66450 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JMV89_RS24635 () | 66577..66897 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| JMV89_RS24640 () | 66945..67642 | - | 698 | Protein_80 | IS1 family transposase IS1G | Transposase |
| JMV89_RS24645 () | 67702..67782 | - | 81 | Protein_81 | type IV conjugative transfer system protein TraL | - |
| JMV89_RS24650 () | 67787..68149 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| JMV89_RS24655 () | 68183..68410 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| JMV89_RS24660 () | 68498..69175 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| JMV89_RS24665 () | 69309..69692 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| JMV89_RS24670 () | 70023..70625 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| JMV89_RS24675 () | 70922..71743 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| JMV89_RS24680 () | 71862..72149 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| JMV89_RS24685 () | 72174..72380 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| JMV89_RS24690 () | 72293..72628 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| JMV89_RS24695 () | 73071..73229 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 73273..73400 | - | 128 | NuclAT_0 | - | - |
| - () | 73273..73400 | - | 128 | NuclAT_0 | - | - |
| - () | 73273..73400 | - | 128 | NuclAT_0 | - | - |
| - () | 73273..73400 | - | 128 | NuclAT_0 | - | - |
| - () | 74842..74944 | - | 103 | NuclAT_1 | - | - |
| - () | 74842..74944 | - | 103 | NuclAT_1 | - | - |
| - () | 74842..74944 | - | 103 | NuclAT_1 | - | - |
| - () | 74842..74944 | - | 103 | NuclAT_1 | - | - |
| JMV89_RS24705 () | 74956..75675 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| JMV89_RS24710 () | 75672..76106 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| JMV89_RS24715 () | 76161..78119 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| JMV89_RS24720 () | 78185..78418 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| JMV89_RS24725 () | 78481..79020 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| JMV89_RS24730 () | 79165..79500 | - | 336 | WP_013023883.1 | hypothetical protein | - |
| JMV89_RS24735 () | 79663..79887 | - | 225 | WP_016238251.1 | hypothetical protein | - |
| JMV89_RS24740 () | 79913..80476 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| JMV89_RS24745 () | 80524..81885 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| JMV89_RS24750 () | 81937..82167 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| JMV89_RS24755 () | 83202..83393 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| JMV89_RS24760 () | 83390..83812 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| JMV89_RS24765 () | 83859..84161 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| JMV89_RS24770 () | 84701..85477 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| JMV89_RS24775 () | 85528..85962 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| JMV89_RS24780 () | 85976..86197 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| JMV89_RS24785 () | 86198..86881 | - | 684 | WP_000086185.1 | DNA methylase | - |
| JMV89_RS24790 () | 86958..87262 | - | 305 | Protein_110 | hypothetical protein | - |
| JMV89_RS24795 () | 87266..88168 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| JMV89_RS24800 () | 89035..90006 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JMV89_RS24805 () | 90006..91172 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| JMV89_RS24810 () | 91760..92515 | - | 756 | WP_024946706.1 | replication initiation protein RepE | - |
| JMV89_RS24815 () | 93289..94095 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| JMV89_RS24820 () | 94096..94401 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JMV89_RS24825 () | 94403..94621 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| JMV89_RS24830 () | 95188..95700 | + | 513 | WP_000151784.1 | hypothetical protein | - |
| JMV89_RS24835 () | 95734..96867 | - | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| JMV89_RS24840 () | 97034..97807 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| JMV89_RS24845 () | 97820..98320 | - | 501 | WP_000528931.1 | hypothetical protein | - |
| JMV89_RS24850 () | 98585..98815 | + | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| JMV89_RS24855 () | 98812..99228 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JMV89_RS24860 () | 99273..103067 | - | 3795 | WP_001144732.1 | hypothetical protein | - |
| JMV89_RS24865 () | 103448..103678 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| JMV89_RS24870 () | 103675..104091 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JMV89_RS24875 () | 104166..105731 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| JMV89_RS24880 () | 105716..106738 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| JMV89_RS24885 () | 106992..107689 | - | 698 | Protein_129 | IS1 family transposase IS1S | Transposase |
| JMV89_RS24890 () | 108045..108959 | + | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| JMV89_RS24895 () | 108959..109786 | + | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| JMV89_RS24900 () | 109783..110640 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| JMV89_RS24905 () | 110637..111494 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| JMV89_RS24910 () | 111983..112396 | + | 414 | Protein_134 | phosphopyruvate hydratase | - |
| JMV89_RS24915 () | 112737..113117 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| JMV89_RS24920 () | 113497..114690 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| JMV89_RS24925 () | 114826..116550 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| JMV89_RS24930 () | 116551..117498 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| JMV89_RS24935 () | 117498..119240 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| JMV89_RS24940 () | 119237..120514 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| JMV89_RS24945 () | 120596..122797 | + | 2202 | WP_201520199.1 | Ferric aerobactin receptor | VF |
| JMV89_RS24950 () | 123177..123874 | + | 698 | Protein_142 | IS1 family transposase IS1S | Transposase |
| JMV89_RS24955 () | 124054..124567 | - | 514 | Protein_143 | DUF4113 domain-containing protein | - |
| JMV89_RS24960 () | 124628..124732 | - | 105 | Protein_144 | AAA family ATPase | - |
| JMV89_RS24965 () | 124734..125057 | - | 324 | Protein_145 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|