MGE detailed information
MGE type: Conjugative plasmid MGE length: 148536 bp
Accession: NZ_CP116243 Location: 1..148536 Organism: Escherichia coli strain 7.1994/NIST0056 Replicon: plasmid unnamed2
Accession: NZ_CP116243 Location: 1..148536 Organism: Escherichia coli strain 7.1994/NIST0056 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PH192_RS23850 (700) | 700..930 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| PH192_RS23855 (1447) | 1447..1700 | + | 254 | Protein_2 | hypothetical protein | - |
| PH192_RS23860 (1924) | 1924..2106 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| PH192_RS23865 (2106) | 2106..2567 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| PH192_RS23870 (2567) | 2567..2992 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| PH192_RS23875 (3135) | 3135..4247 | + | 1113 | WP_271356493.1 | IS4 family transposase IS421 | Transposase |
| PH192_RS23880 (4440) | 4440..4609 | - | 170 | Protein_7 | hypothetical protein | - |
| PH192_RS23885 (4988) | 4988..5959 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PH192_RS23890 (5959) | 5959..7125 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| PH192_RS23900 (8219) | 8219..8386 | - | 168 | WP_000638861.1 | hypothetical protein | - |
| PH192_RS23905 (8636) | 8636..10138 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| PH192_RS23910 (10764) | 10764..11189 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| PH192_RS23915 (11331) | 11331..11810 | + | 480 | WP_000190054.1 | hypothetical protein | - |
| PH192_RS23920 (12250) | 12250..12912 | + | 663 | WP_000163251.1 | hypothetical protein | - |
| PH192_RS23930 (14145) | 14145..16346 | - | 2202 | WP_000973517.1 | Ferric aerobactin receptor | VF |
| PH192_RS23935 (16372) | 16372..17705 | - | 1334 | Protein_18 | L-lysine N6-monooxygenase | VF |
| PH192_RS23940 (17702) | 17702..19444 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| PH192_RS23945 (19444) | 19444..20391 | - | 948 | WP_000011907.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| PH192_RS23950 (20392) | 20392..22116 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| PH192_RS23955 (22252) | 22252..23445 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| PH192_RS23960 (23825) | 23825..24205 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| PH192_RS23965 (24546) | 24546..24959 | - | 414 | Protein_24 | phosphopyruvate hydratase | - |
| PH192_RS23970 (24957) | 24957..25214 | + | 258 | Protein_25 | Tn3 family transposase | - |
| PH192_RS23975 (25448) | 25448..26305 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| PH192_RS23980 (26302) | 26302..27159 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| PH192_RS23985 (27156) | 27156..27983 | - | 828 | WP_000983712.1 | Manganese transport system ATP-binding protein MntB | VF |
| PH192_RS23990 (27983) | 27983..28897 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| PH192_RS23995 (29253) | 29253..29950 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| PH192_RS24000 (30130) | 30130..30643 | - | 514 | Protein_31 | DUF4113 domain-containing protein | - |
| PH192_RS24005 (30704) | 30704..30808 | - | 105 | Protein_32 | AAA family ATPase | - |
| PH192_RS24010 (30810) | 30810..31133 | - | 324 | Protein_33 | IS21 family transposase IS21 | Transposase |
| PH192_RS24015 (31879) | 31879..32856 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| PH192_RS24020 (33141) | 33141..33881 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| PH192_RS24025 (34002) | 34002..34190 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| PH192_RS24030 (34564) | 34564..35466 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| PH192_RS24035 (35535) | 35535..36644 | - | 1110 | WP_271356494.1 | SDR family oxidoreductase | - |
| PH192_RS24040 (37077) | 37077..38030 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| PH192_RS24045 (39327) | 39327..39506 | - | 180 | Protein_40 | integrase core domain-containing protein | - |
| PH192_RS24050 (39645) | 39645..40858 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| PH192_RS24055 (41006) | 41006..41331 | - | 326 | Protein_42 | IS3 family transposase ISLad1 | Transposase |
| PH192_RS24060 (41377) | 41377..41717 | + | 341 | Protein_43 | IS3 family transposase | - |
| PH192_RS24065 (42312) | 42312..43499 | + | 1188 | WP_000928803.1 | efflux RND transporter periplasmic adaptor subunit | - |
| PH192_RS24070 (43496) | 43496..45436 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| PH192_RS24075 (45440) | 45440..46810 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| PH192_RS24080 (47284) | 47284..47478 | + | 195 | Protein_47 | IS200-IS605 family transposase IS200C | Transposase |
| PH192_RS24085 (47607) | 47607..48548 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| PH192_RS24090 (48783) | 48783..50168 | - | 1386 | Protein_49 | ISNCY family transposase ISKpn21 | Transposase |
| PH192_RS24095 (50478) | 50478..50627 | - | 150 | Protein_50 | IS3 family transposase IS2 | Transposase |
| PH192_RS24100 (50805) | 50805..51998 | - | 1194 | WP_000450495.1 | GTP-binding protein | - |
| PH192_RS24110 (55077) | 55077..55370 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| PH192_RS24115 (55428) | 55428..55627 | - | 200 | Protein_54 | lysis protein | - |
| PH192_RS24120 (56181) | 56181..57200 | + | 1020 | Protein_55 | integrase core domain-containing protein | - |
| PH192_RS24125 (58511) | 58511..59626 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| PH192_RS24130 (59766) | 59766..63425 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| PH192_RS24135 (63529) | 63529..64758 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| PH192_RS24140 (64843) | 64843..65799 | + | 957 | WP_000271276.1 | hypothetical protein | VF |
| PH192_RS24145 (65844) | 65844..68021 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| PH192_RS24150 (68876) | 68876..69010 | - | 135 | WP_249531455.1 | hypothetical protein | - |
| PH192_RS24155 (68970) | 68970..69911 | - | 942 | WP_001312841.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| PH192_RS24160 (70092) | 70092..70392 | + | 301 | Protein_63 | hypothetical protein | - |
| PH192_RS24165 (70470) | 70470..70817 | - | 348 | WP_000142437.1 | DUF6404 family protein | - |
| PH192_RS24170 (71119) | 71119..71601 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| PH192_RS24175 (71718) | 71718..72566 | - | 849 | WP_001058005.1 | 3'-5' exonuclease | - |
| PH192_RS24180 (72612) | 72612..72890 | - | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| PH192_RS24185 (72890) | 72890..73159 | - | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| PH192_RS24190 (73681) | 73681..74909 | + | 1229 | WP_112030635.1 | IS3 family transposase IS2 | Transposase |
| PH192_RS24195 (75106) | 75106..76380 | + | 1275 | WP_000489607.1 | HlyD family secretion protein | - |
| PH192_RS24200 (76487) | 76487..76759 | + | 273 | Protein_71 | IS4 family transposase IS421 | Transposase |
| PH192_RS24205 (76940) | 76940..77926 | + | 987 | Protein_72 | IS4 family transposase IS421 | Transposase |
| PH192_RS24210 (78550) | 78550..78753 | - | 204 | Protein_73 | hypothetical protein | - |
| PH192_RS24215 (78926) | 78926..79093 | + | 168 | Protein_74 | colicin-B | - |
| PH192_RS24220 (79111) | 79111..79638 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| PH192_RS24225 (79882) | 79882..80697 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| PH192_RS24230 (80747) | 80747..81100 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| PH192_RS24235 (81278) | 81278..82069 | - | 792 | WP_000016494.1 | site-specific integrase | - |
| PH192_RS24240 (82066) | 82066..82755 | - | 690 | WP_000796229.1 | hypothetical protein | - |
| PH192_RS24245 (82799) | 82799..83149 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| PH192_RS24250 (83753) | 83753..83983 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PH192_RS24255 (83980) | 83980..84396 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PH192_RS24260 (84471) | 84471..86036 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| PH192_RS24265 (86021) | 86021..87043 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| PH192_RS24275 (87877) | 87877..92010 | - | 4134 | WP_001080138.1 | Hemoglobin-binding protease hbp autotransporter | VF |
| PH192_RS24280 (92279) | 92279..93491 | + | 1213 | Protein_87 | IS3 family transposase | - |
| PH192_RS24285 (93760) | 93760..94047 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| PH192_RS24290 (94044) | 94044..94295 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| PH192_RS24295 (95258) | 95258..96115 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| PH192_RS24300 (96108) | 96108..96590 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| PH192_RS24305 (96583) | 96583..96630 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| PH192_RS24310 (96621) | 96621..96872 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| PH192_RS24315 (96889) | 96889..97146 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| PH192_RS24320 (97430) | 97430..97579 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (97623) | 97623..97684 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (97623) | 97623..97684 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (97623) | 97623..97684 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (97623) | 97623..97684 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| PH192_RS24325 (97940) | 97940..98014 | - | 75 | Protein_96 | endonuclease | - |
| PH192_RS24330 (98260) | 98260..98472 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| PH192_RS24335 (98549) | 98549..99212 | + | 664 | Protein_98 | IS66 family transposase ISCro1 | Transposase |
| PH192_RS24340 (99228) | 99228..99575 | + | 348 | WP_271356481.1 | IS66 family transposase ISCro1 | Transposase |
| PH192_RS24345 (99595) | 99595..99876 | + | 282 | WP_271356486.1 | IS66 family transposase ISCro1 | Transposase |
| PH192_RS24350 (99794) | 99794..101167 | + | 1374 | WP_271356489.1 | IS66 family transposase ISCro1 | Transposase |
| PH192_RS24355 (101318) | 101318..101878 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| PH192_RS24360 (101981) | 101981..102841 | - | 861 | WP_000704513.1 | Quorum-quenching protein AidA | VF |
| PH192_RS24365 (102900) | 102900..103646 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| PH192_RS24370 (103666) | 103666..108381 | - | 4716 | Protein_105 | Multifunctional conjugation protein TraI | Relaxase |
| PH192_RS24380 (109153) | 109153..109713 | - | 561 | Protein_107 | Multifunctional conjugation protein TraI | Relaxase |
| PH192_RS24385 (109795) | 109795..110022 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| PH192_RS24390 (110022) | 110022..110420 | + | 399 | WP_000911333.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| PH192_RS24395 (110429) | 110429..112582 | - | 2154 | WP_000009325.1 | type IV conjugative transfer system coupling protein TraD | - |
| PH192_RS24400 (112835) | 112835..113566 | - | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| PH192_RS24405 (113580) | 113580..114089 | - | 510 | WP_000628107.1 | conjugal transfer entry exclusion protein TraS | - |
| PH192_RS24410 (114086) | 114086..116911 | - | 2826 | WP_271356490.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PH192_RS24415 (116908) | 116908..118281 | - | 1374 | WP_000944319.1 | conjugal transfer pilus assembly protein TraH | - |
| PH192_RS24420 (118268) | 118268..118660 | - | 393 | Protein_115 | F-type conjugal transfer protein TrbF | - |
| PH192_RS24425 (118647) | 118647..118988 | - | 342 | WP_001442101.1 | P-type conjugative transfer protein TrbJ | - |
| PH192_RS24430 (118918) | 118918..119463 | - | 546 | WP_000059833.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PH192_RS24435 (119450) | 119450..119734 | - | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PH192_RS24440 (119937) | 119937..120683 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| PH192_RS24445 (120698) | 120698..122239 | - | 1542 | WP_271356491.1 | IS21 family transposase ISEc12 | Transposase |
| PH192_RS24450 (122485) | 122485..122760 | + | 276 | WP_001513501.1 | hypothetical protein | - |
| PH192_RS24455 (122762) | 122762..123109 | - | 348 | WP_001287907.1 | conjugal transfer protein TrbA | - |
| PH192_RS24460 (123125) | 123125..123868 | - | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PH192_RS24465 (123861) | 123861..124118 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| PH192_RS24470 (124145) | 124145..125953 | - | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PH192_RS24475 (125950) | 125950..126588 | - | 639 | WP_000777688.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PH192_RS24480 (126597) | 126597..127589 | - | 993 | WP_000830187.1 | conjugal transfer pilus assembly protein TraU | - |
| PH192_RS24485 (127586) | 127586..128218 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| PH192_RS24490 (128215) | 128215..128601 | - | 387 | WP_000097319.1 | type-F conjugative transfer system protein TrbI | - |
| PH192_RS24495 (128598) | 128598..131225 | - | 2628 | WP_001064247.1 | type IV secretion system protein TraC | - |
| PH192_RS24500 (131385) | 131385..131606 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| PH192_RS24505 (131741) | 131741..132256 | - | 516 | WP_000809841.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PH192_RS24510 (132253) | 132253..132504 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| PH192_RS24515 (132516) | 132516..132713 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| PH192_RS24520 (132700) | 132700..133290 | - | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PH192_RS24525 (133280) | 133280..134707 | - | 1428 | WP_000146692.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PH192_RS24530 (134707) | 134707..135435 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| PH192_RS24535 (135422) | 135422..135988 | - | 567 | WP_089625909.1 | type IV conjugative transfer system protein TraE | - |
| PH192_RS24540 (136010) | 136010..136321 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| PH192_RS24545 (136336) | 136336..136701 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| PH192_RS24550 (136734) | 136734..137135 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| PH192_RS24555 (137228) | 137228..137917 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| PH192_RS24560 (138104) | 138104..138487 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PH192_RS24565 (138808) | 138808..139410 | + | 603 | WP_000243709.1 | hypothetical protein | VF |
| PH192_RS24570 (139707) | 139707..140528 | - | 822 | WP_001234480.1 | DUF932 domain-containing protein | - |
| PH192_RS24575 (140648) | 140648..140935 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| PH192_RS24580 (140960) | 140960..141166 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| PH192_RS24585 (141236) | 141236..141409 | + | 174 | Protein_148 | hypothetical protein | - |
| PH192_RS24590 (141407) | 141407..141637 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| PH192_RS24595 (141857) | 141857..141982 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PH192_RS24600 (141924) | 141924..142073 | - | 150 | Protein_151 | plasmid maintenance protein Mok | - |
| - (142059) | 142059..142283 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (142059) | 142059..142283 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (142059) | 142059..142283 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (142059) | 142059..142283 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| PH192_RS24605 (142095) | 142095..142283 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| PH192_RS24610 (142252) | 142252..143014 | - | 763 | Protein_153 | plasmid SOS inhibition protein A | - |
| PH192_RS24615 (143011) | 143011..143445 | - | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| PH192_RS24620 (143500) | 143500..145458 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| PH192_RS24625 (145517) | 145517..145750 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| PH192_RS24630 (145806) | 145806..146333 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| PH192_RS24635 (146806) | 146806..147060 | - | 255 | WP_072163210.1 | hypothetical protein | - |
| PH192_RS24640 (146976) | 146976..147215 | - | 240 | WP_240724493.1 | hypothetical protein | - |
| PH192_RS24645 (147212) | 147212..147775 | - | 564 | WP_001332335.1 | class I SAM-dependent methyltransferase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|