NZ_CP0838841..164740

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 164740 bp
Accession: NZ_CP083884        Location: 1..164740         Organism: Escherichia coli strain NDM2       Replicon: plasmid unnamed1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCE23_RS00010 (91) 91..2055 + 1965 WP_224446720.1 ParB/RepB/Spo0J family partition protein -
LCE23_RS00015 (2124) 2124..2558 + 435 WP_000845962.1 conjugation system SOS inhibitor PsiB -
LCE23_RS00020 (2555) 2555..3317 + 763 Protein_3 plasmid SOS inhibition protein A -
- (3286) 3286..3510 + 225 NuclAT_0 - -
- (3286) 3286..3510 + 225 NuclAT_0 - -
- (3286) 3286..3510 + 225 NuclAT_0 - -
- (3286) 3286..3510 + 225 NuclAT_0 - -
LCE23_RS00025 (3496) 3496..3645 + 150 Protein_4 plasmid maintenance protein Mok -
LCE23_RS00030 (3596) 3596..3712 + 117 WP_001375150.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LCE23_RS00035 (4013) 4013..4286 - 274 Protein_6 hypothetical protein -
LCE23_RS00040 (4338) 4338..4634 + 297 WP_001272245.1 hypothetical protein -
LCE23_RS00045 (4745) 4745..5566 + 822 WP_001234487.1 DUF932 domain-containing protein -
LCE23_RS00050 (5863) 5863..6465 - 603 WP_077250849.1 hypothetical protein VF
LCE23_RS00055 (6786) 6786..7169 + 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
LCE23_RS00060 (7356) 7356..8045 + 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
LCE23_RS00065 (8138) 8138..8539 + 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
LCE23_RS00070 (8572) 8572..8937 + 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
LCE23_RS00075 (8952) 8952..9263 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LCE23_RS00080 (9285) 9285..9851 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
LCE23_RS00085 (9838) 9838..10566 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
LCE23_RS00090 (10566) 10566..11993 + 1428 WP_000146685.1 F-type conjugal transfer pilus assembly protein TraB -
LCE23_RS00095 (11983) 11983..12573 + 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
LCE23_RS00100 (12560) 12560..12757 + 198 WP_001324648.1 conjugal transfer protein TrbD -
LCE23_RS00105 (12769) 12769..13020 + 252 WP_001038342.1 conjugal transfer protein TrbG -
LCE23_RS00110 (13017) 13017..13532 + 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
LCE23_RS00115 (13667) 13667..13888 + 222 WP_001278689.1 conjugal transfer protein TraR -
LCE23_RS00120 (14048) 14048..16675 + 2628 WP_001064245.1 type IV secretion system protein TraC -
LCE23_RS00125 (16672) 16672..17058 + 387 WP_001680293.1 type-F conjugative transfer system protein TrbI -
LCE23_RS00130 (17055) 17055..17687 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
LCE23_RS00135 (17684) 17684..18676 + 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
LCE23_RS00140 (18685) 18685..19323 + 639 WP_000777695.1 type-F conjugative transfer system pilin assembly protein TrbC -
LCE23_RS00145 (19320) 19320..21128 + 1809 WP_000821849.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LCE23_RS00150 (21155) 21155..21412 + 258 WP_072748671.1 conjugal transfer protein TrbE -
LCE23_RS00155 (21405) 21405..22148 + 744 WP_001680292.1 type-F conjugative transfer system pilin assembly protein TraF -
LCE23_RS00160 (22164) 22164..22511 + 348 WP_001287910.1 conjugal transfer protein TrbA -
LCE23_RS00165 (22513) 22513..22827 - 315 WP_000415566.1 protein ArtA -
LCE23_RS00170 (22908) 22908..23192 + 285 WP_000624109.1 type-F conjugative transfer system pilin chaperone TraQ -
LCE23_RS00175 (23179) 23179..23724 + 546 WP_001680291.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LCE23_RS00180 (23654) 23654..23995 + 342 WP_001443031.1 P-type conjugative transfer protein TrbJ -
LCE23_RS00185 (23982) 23982..24362 + 381 WP_001680290.1 F-type conjugal transfer protein TrbF -
LCE23_RS00190 (24362) 24362..25735 + 1374 WP_001517790.1 conjugal transfer pilus assembly protein TraH -
LCE23_RS00195 (25732) 25732..28554 + 2823 WP_001007018.1 conjugal transfer mating-pair stabilization protein TraG -
LCE23_RS00200 (28570) 28570..29067 + 498 WP_000605857.1 entry exclusion protein -
LCE23_RS00205 (29099) 29099..29830 + 732 WP_023565183.1 conjugal transfer complement resistance protein TraT -
LCE23_RS00210 (30083) 30083..32281 + 2199 WP_001593043.1 type IV conjugative transfer system coupling protein TraD -
LCE23_RS00215 (32290) 32290..32688 - 399 WP_000911313.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LCE23_RS00220 (32688) 32688..32915 - 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
LCE23_RS00225 (32997) 32997..38267 + 5271 WP_001611029.1 Multifunctional conjugation protein TraI Relaxase
LCE23_RS00230 (38287) 38287..39033 + 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
LCE23_RS00235 (39092) 39092..39952 + 861 WP_000704513.1 putative protein YcjY VF
LCE23_RS00240 (40055) 40055..40615 + 561 WP_000139315.1 fertility inhibition protein FinO -
LCE23_RS00245 (40751) 40751..40963 + 213 WP_001299730.1 ANR family transcriptional regulator -
LCE23_RS00250 (41209) 41209..41283 + 75 Protein_49 endonuclease -
- (41539) 41539..41600 - 62 NuclAT_1 - Antitoxin Detail
- (41539) 41539..41600 - 62 NuclAT_1 - Antitoxin Detail
- (41539) 41539..41600 - 62 NuclAT_1 - Antitoxin Detail
- (41539) 41539..41600 - 62 NuclAT_1 - Antitoxin Detail
LCE23_RS00255 (41644) 41644..41793 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
LCE23_RS00260 (42077) 42077..42334 + 258 WP_000083845.1 replication regulatory protein RepA -
LCE23_RS00265 (42351) 42351..42602 - 252 WP_223195197.1 replication protein RepA -
LCE23_RS00270 (42593) 42593..42640 + 48 WP_229471593.1 hypothetical protein -
LCE23_RS00275 (42633) 42633..43115 + 483 WP_001273588.1 hypothetical protein -
LCE23_RS00280 (43108) 43108..43965 + 858 WP_000774297.1 incFII family plasmid replication initiator RepA -
LCE23_RS00285 (44904) 44904..45557 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LCE23_RS00290 (45650) 45650..45907 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LCE23_RS00295 (45840) 45840..46241 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LCE23_RS00300 (46526) 46526..47047 + 522 WP_224446721.1 DUF262 domain-containing protein -
LCE23_RS00305 (47098) 47098..47835 + 738 WP_224271570.1 hypothetical protein -
LCE23_RS00310 (47864) 47864..48561 + 698 WP_095033700.1 IS1-like element IS1B family transposase -
LCE23_RS00315 (48572) 48572..48784 - 213 WP_252369513.1 hypothetical protein -
LCE23_RS00320 (48775) 48775..49026 + 252 WP_000928197.1 exosortase H-associated membrane protein -
LCE23_RS00325 (49034) 49034..49312 - 279 WP_001611016.1 diguanylate cyclase -
LCE23_RS00330 (49394) 49394..50122 + 729 WP_000059618.1 IS91 family transposase ISPps1 Transposase
LCE23_RS00335 (50224) 50224..51747 + 1524 WP_001324342.1 IS21 family transposase IS1326 Transposase
LCE23_RS00340 (51737) 51737..52519 + 783 WP_001163403.1 IS21 family transposase IS1326 Transposase
LCE23_RS00345 (52695) 52695..53195 - 501 WP_000376623.1 GNAT family N-acetyltransferase -
LCE23_RS00350 (53323) 53323..54162 - 840 WP_000259031.1 Dihydropteroate synthase ARG
LCE23_RS00355 (54156) 54156..54503 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
LCE23_RS00360 (54620) 54620..55458 - 839 Protein_71 Streptomycin 3''-adenylyltransferase ARG
LCE23_RS00365 (55551) 55551..56024 - 474 WP_000777555.1 Dihydrofolate reductase type 1 ARG
LCE23_RS00370 (56181) 56181..57299 + 1119 WP_000845049.1 IS91 family transposase ISAzo26 Transposase
LCE23_RS00375 (57271) 57271..57999 - 729 Protein_74 APH(6)-I family aminoglycoside O-phosphotransferase -
LCE23_RS00380 (58063) 58063..58767 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
LCE23_RS00385 (58773) 58773..58913 + 141 WP_001044210.1 hypothetical protein -
LCE23_RS00390 (59399) 59399..60136 + 738 WP_001366550.1 Tn3 family transposase TnpR_TnEc1 Transposase
LCE23_RS00395 (60133) 60133..60357 + 225 WP_000743213.1 hypothetical protein -
LCE23_RS00400 (60568) 60568..62061 + 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
LCE23_RS00405 (62092) 62092..62976 + 885 WP_001447541.1 DUF3363 domain-containing protein -
LCE23_RS00410 (63193) 63193..64407 + 1215 WP_000214121.1 Bicyclomycin resistance protein ARG
LCE23_RS00415 (64435) 64435..64740 + 306 WP_224446722.1 HTH-type transcriptional regulator CynR VF
LCE23_RS00420 (64852) 64852..65040 + 189 Protein_83 IS91 family transposase -
LCE23_RS00425 (65007) 65007..66205 - 1199 Protein_84 tetracycline efflux MFS transporter Tet(A) -
LCE23_RS00430 (66306) 66306..66956 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
LCE23_RS00435 (67021) 67021..70026 - 3006 WP_001143775.1 Tn3 family transposase TnpA_Tn3 Transposase
LCE23_RS00440 (70188) 70188..70745 + 558 WP_001217881.1 Tn3 family transposase TnpR_Tn3 Transposase
LCE23_RS00445 (70928) 70928..71787 + 860 Protein_88 Beta-lactamase TEM ARG
LCE23_RS00450 (71949) 71949..72764 + 816 WP_001043260.1 Dihydropteroate synthase ARG
LCE23_RS00455 (72825) 72825..73628 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
LCE23_RS00460 (73628) 73628..74463 + 836 Protein_91 hypothetical protein ARG
LCE23_RS00465 (74769) 74769..75011 + 243 WP_000844627.1 transposase -
LCE23_RS00470 (75043) 75043..75693 - 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
LCE23_RS00475 (75799) 75799..76992 + 1194 Protein_94 hypothetical protein ARG
LCE23_RS00480 (77024) 77024..77907 - 884 Protein_95 EamA family transporter -
LCE23_RS00485 (78045) 78045..78437 - 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
LCE23_RS00490 (78441) 78441..80191 + 1751 Protein_97 Tn3 family transposase TnpA_TnAs1 Transposase
LCE23_RS00495 (81397) 81397..82421 - 1025 Protein_98 integrase core domain-containing protein -
LCE23_RS00500 (82975) 82975..83172 + 198 Protein_99 lysis protein -
LCE23_RS00510 (83230) 83230..83523 - 294 WP_000738422.1 increased serum survival lipoprotein Iss -
LCE23_RS00515 (84193) 84193..85261 + 1069 Protein_101 IS3 family transposase IS2 Transposase
LCE23_RS00525 (86517) 86517..86684 + 168 Protein_103 integrase core domain-containing protein -
LCE23_RS00530 (87881) 87881..89075 + 1195 Protein_104 GTP-binding protein -
LCE23_RS00535 (89253) 89253..89402 + 150 Protein_105 IS3 family transposase IS2 Transposase
LCE23_RS00540 (89712) 89712..91108 + 1397 Protein_106 ISNCY family transposase ISKpn21 Transposase
LCE23_RS00545 (91343) 91343..92284 + 942 WP_000974762.1 hypothetical protein -
LCE23_RS00550 (92413) 92413..92607 - 195 Protein_108 IS200-IS605 family transposase IS200C Transposase
LCE23_RS00555 (93081) 93081..94451 - 1371 WP_001312828.1 efflux transporter outer membrane subunit -
LCE23_RS00560 (94455) 94455..96395 - 1941 WP_000733250.1 Macrolide export ATP-binding/permease protein MacB VF
LCE23_RS00565 (96392) 96392..97579 - 1188 WP_000928804.1 efflux RND transporter periplasmic adaptor subunit -
LCE23_RS00570 (98174) 98174..98514 - 341 Protein_112 IS3 family transposase -
LCE23_RS00575 (98560) 98560..98885 + 326 Protein_113 IS3 family transposase IS911 Transposase
LCE23_RS00580 (99033) 99033..100232 - 1200 Protein_114 IS3 family transposase IS629 Transposase
LCE23_RS00585 (100371) 100371..100550 + 180 Protein_115 transposase -
LCE23_RS00590 (101846) 101846..102799 + 954 WP_000280980.1 Protease 7 VF
LCE23_RS00595 (103232) 103232..104341 + 1110 WP_000771475.1 SDR family oxidoreductase -
LCE23_RS00600 (104410) 104410..105312 + 903 WP_001312822.1 hypothetical protein VF
LCE23_RS00605 (105686) 105686..105874 + 189 WP_001312821.1 hypothetical protein -
LCE23_RS00610 (105995) 105995..106735 + 741 WP_001066954.1 tyrosine-type recombinase/integrase -
LCE23_RS00615 (107020) 107020..107997 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
LCE23_RS00620 (108741) 108741..109064 + 324 Protein_122 IS21 family transposase IS21 Transposase
LCE23_RS00625 (109066) 109066..109170 + 105 Protein_123 AAA family ATPase -
LCE23_RS00630 (109231) 109231..109744 + 514 Protein_124 DUF4113 domain-containing protein -
LCE23_RS00640 (110977) 110977..111891 + 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
LCE23_RS00645 (111891) 111891..112718 + 828 WP_000983712.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
LCE23_RS00650 (112715) 112715..113572 + 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
LCE23_RS00655 (113569) 113569..114426 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
LCE23_RS00660 (114915) 114915..115328 + 414 Protein_130 phosphopyruvate hydratase -
LCE23_RS00665 (115669) 115669..116049 + 381 WP_001318207.1 fluoride efflux transporter CrcB -
LCE23_RS00670 (116429) 116429..117622 - 1194 WP_000095526.1 MFS transporter -
LCE23_RS00675 (117758) 117758..119482 + 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
LCE23_RS00680 (119483) 119483..120430 + 948 WP_000011907.1 N(6)-hydroxylysine O-acetyltransferase VF
LCE23_RS00685 (120430) 120430..122172 + 1743 WP_001015721.1 Aerobactin synthase VF
LCE23_RS00690 (122169) 122169..123502 + 1334 Protein_136 L-lysine N6-monooxygenase VF
LCE23_RS00695 (123528) 123528..125729 + 2202 WP_000973517.1 Ferric aerobactin receptor VF
LCE23_RS00700 (126234) 126234..126931 + 698 WP_223155668.1 IS1 family transposase IS1S Transposase
LCE23_RS00705 (127185) 127185..128207 - 1023 WP_000361402.1 helicase UvrD -
LCE23_RS00710 (128192) 128192..129757 - 1566 WP_001128474.1 AAA family ATPase -
LCE23_RS00715 (129832) 129832..130248 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LCE23_RS00720 (130245) 130245..130475 - 231 WP_088569139.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
LCE23_RS00725 (130862) 130862..133000 + 2139 WP_001513523.1 AAA family ATPase -
LCE23_RS00730 (133162) 133162..133578 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LCE23_RS00735 (133575) 133575..133805 - 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
LCE23_RS00740 (134224) 134224..134913 + 690 WP_001513524.1 RES family NAD+ phosphorylase -
LCE23_RS00745 (134944) 134944..135633 - 690 WP_001513525.1 helix-turn-helix domain-containing protein -
LCE23_RS00750 (136189) 136189..136407 + 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
LCE23_RS00755 (136409) 136409..136714 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
LCE23_RS00760 (136715) 136715..137461 + 747 WP_072748653.1 site-specific integrase -
LCE23_RS00765 (138161) 138161..138310 + 150 Protein_151 RepB family plasmid replication initiator protein -
LCE23_RS00775 (139716) 139716..140162 + 447 WP_000616196.1 hypothetical protein -
LCE23_RS00780 (140258) 140258..140515 - 258 WP_015387373.1 hypothetical protein -
LCE23_RS00785 (141244) 141244..141456 + 213 WP_001523378.1 hypothetical protein -
LCE23_RS00790 (142583) 142583..142759 - 177 WP_001513516.1 lasso peptide microcin J25 -
LCE23_RS00795 (143099) 143099..143725 + 627 WP_001513515.1 lasso peptide biosynthesis B2 protein -
LCE23_RS00800 (143728) 143728..145269 + 1542 WP_001513514.1 lasso peptide isopeptide bond-forming cyclase -
LCE23_RS00805 (145272) 145272..147014 + 1743 WP_001513513.1 ABC transporter ATP-binding protein -
LCE23_RS00810 (147339) 147339..147827 - 489 Protein_160 Tn3 family transposase TnpR_TnEc1 Transposase
LCE23_RS00815 (147885) 147885..148582 + 698 WP_223230354.1 IS1 family transposase IS1S Transposase
LCE23_RS00820 (148882) 148882..150048 + 1167 WP_001238646.1 Sporulation initiation inhibitor protein Soj VF
LCE23_RS00825 (150048) 150048..151019 + 972 WP_000817028.1 ParB/RepB/Spo0J family plasmid partition protein -
LCE23_RS00830 (151999) 151999..152168 + 170 Protein_164 hypothetical protein -
LCE23_RS00835 (152245) 152245..153360 + 1116 WP_224446719.1 IS4 family transposase IS421 Transposase
LCE23_RS00840 (153933) 153933..154508 + 576 WP_000343071.1 hypothetical protein -
LCE23_RS00850 (156255) 156255..157226 - 972 WP_072647562.1 IS110 family transposase ISEc32 Transposase
LCE23_RS00855 (157628) 157628..158053 + 426 WP_001198930.1 antirestriction protein -
LCE23_RS00860 (158100) 158100..158522 + 423 WP_001593056.1 DUF1380 family protein -
LCE23_RS00865 (158519) 158519..158701 + 183 WP_001027505.1 hypothetical protein -
LCE23_RS00870 (158925) 158925..159178 - 254 Protein_172 hypothetical protein -
LCE23_RS00875 (159693) 159693..159923 + 231 WP_000218649.1 hypothetical protein -
LCE23_RS00880 (159975) 159975..161336 + 1362 WP_001593055.1 DUF3560 domain-containing protein -
LCE23_RS00885 (161383) 161383..161946 + 564 WP_001333938.1 class I SAM-dependent methyltransferase -
LCE23_RS00890 (162032) 162032..162458 - 427 Protein_176 hypothetical protein -
LCE23_RS00895 (162418) 162418..163389 - 972 WP_072647560.1 IS110 family transposase ISSm3 Transposase
LCE23_RS00900 (163560) 163560..163640 - 81 Protein_178 hypothetical protein -
LCE23_RS00905 (163710) 163710..163916 + 207 WP_000547969.1 hypothetical protein -
LCE23_RS00910 (163942) 163942..164481 + 540 WP_072647559.1 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance