MGE detailed information
MGE type: Conjugative plasmid MGE length: 158291 bp
Accession: NZ_CP074681 Location: 1..158291 Organism: Escherichia coli strain MEI008 Replicon: plasmid pMEI008_1
Accession: NZ_CP074681 Location: 1..158291 Organism: Escherichia coli strain MEI008 Replicon: plasmid pMEI008_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KIM92_RS23550 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KIM92_RS23555 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| KIM92_RS23560 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| KIM92_RS23565 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| KIM92_RS23570 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| KIM92_RS23575 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| KIM92_RS23580 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| KIM92_RS23585 (7767) | 7767..8966 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| KIM92_RS23590 (9114) | 9114..9439 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| KIM92_RS23595 (9485) | 9485..9825 | + | 341 | Protein_9 | IS3 family transposase | - |
| KIM92_RS23600 (10420) | 10420..11607 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| KIM92_RS23605 (11604) | 11604..13544 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| KIM92_RS23610 (13548) | 13548..14918 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| KIM92_RS23615 (15392) | 15392..15586 | + | 195 | Protein_13 | IS200/IS605-like element IS200C family transposase | - |
| KIM92_RS23620 (15715) | 15715..16656 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| KIM92_RS23625 (16891) | 16891..18280 | - | 1390 | Protein_15 | ISNCY family transposase ISKpn21 | Transposase |
| KIM92_RS23630 (18590) | 18590..18739 | - | 150 | Protein_16 | IS3 family transposase IS2 | Transposase |
| KIM92_RS23635 (18917) | 18917..20110 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| KIM92_RS23640 (21352) | 21352..22089 | - | 738 | Protein_18 | IS3 family transposase IS2 | Transposase |
| KIM92_RS23645 (22142) | 22142..23304 | + | 1163 | WP_085947598.1 | IS3 family transposase ISEc17 | Transposase |
| KIM92_RS23650 (23321) | 23321..23841 | - | 521 | Protein_20 | IS3 family transposase IS2 | Transposase |
| KIM92_RS23655 (24466) | 24466..24759 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| KIM92_RS23660 (24817) | 24817..25016 | - | 200 | Protein_22 | lysis protein | - |
| KIM92_RS23665 (25570) | 25570..26594 | + | 1025 | Protein_23 | integrase core domain-containing protein | - |
| KIM92_RS23670 (27905) | 27905..29020 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| KIM92_RS23675 (29160) | 29160..32819 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| KIM92_RS23680 (32923) | 32923..34152 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| KIM92_RS23685 (34237) | 34237..35193 | + | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| KIM92_RS23690 (35238) | 35238..37415 | - | 2178 | WP_001222185.1 | Ferric enterobactin receptor | VF |
| KIM92_RS23695 (38281) | 38281..39315 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| KIM92_RS23700 (39496) | 39496..39797 | + | 302 | Protein_30 | hypothetical protein | - |
| KIM92_RS23705 (39875) | 39875..40168 | - | 294 | WP_000269327.1 | DUF6404 family protein | - |
| KIM92_RS23710 (40336) | 40336..40461 | - | 126 | Protein_32 | type II toxin-antitoxin system toxin YacB | - |
| KIM92_RS23715 (40461) | 40461..40729 | - | 269 | Protein_33 | type II toxin-antitoxin system antitoxin YacA | - |
| KIM92_RS23720 (41340) | 41340..42614 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| KIM92_RS23725 (42607) | 42607..44703 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| KIM92_RS23730 (44873) | 44873..45184 | - | 312 | WP_001259758.1 | colicin V | - |
| KIM92_RS23735 (45162) | 45162..45398 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| KIM92_RS23740 (45517) | 45517..45960 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| KIM92_RS23745 (45932) | 45932..46336 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| KIM92_RS23750 (46338) | 46338..46607 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| KIM92_RS23755 (46604) | 46604..47584 | + | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| KIM92_RS23760 (47660) | 47660..48040 | + | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| KIM92_RS23765 (48037) | 48037..48384 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| KIM92_RS23770 (48434) | 48434..49971 | + | 1538 | Protein_44 | IS66 family transposase ISEc8 | Transposase |
| KIM92_RS23775 (50011) | 50011..50277 | + | 267 | Protein_45 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| KIM92_RS23780 (50324) | 50324..50716 | - | 393 | Protein_46 | peptide deformylase | - |
| KIM92_RS23785 (50825) | 50825..54958 | - | 4134 | WP_001080137.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| KIM92_RS23790 (55129) | 55129..55320 | + | 192 | Protein_48 | IS91 family transposase | - |
| KIM92_RS23795 (55599) | 55599..55856 | + | 258 | Protein_49 | IS3 family transposase IS911 | Transposase |
| KIM92_RS23800 (55924) | 55924..57075 | + | 1152 | WP_001442799.1 | IS30 family transposase IS30D | Transposase |
| KIM92_RS23805 (57197) | 57197..57562 | + | 366 | WP_000124098.1 | hypothetical protein | - |
| KIM92_RS23810 (57562) | 57562..58677 | + | 1116 | Protein_52 | IS91 family transposase IS91 | Transposase |
| KIM92_RS23815 (58858) | 58858..59202 | - | 345 | WP_001553768.1 | hypothetical protein | - |
| KIM92_RS23820 (60060) | 60060..63026 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KIM92_RS23825 (63030) | 63030..63590 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| KIM92_RS23830 (63900) | 63900..65477 | + | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| KIM92_RS23835 (65754) | 65754..66614 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KIM92_RS23840 (66797) | 66797..67354 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KIM92_RS23845 (67518) | 67518..70523 | + | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KIM92_RS23850 (70456) | 70456..70921 | - | 466 | Protein_60 | plasmid replication initiator RepA | - |
| KIM92_RS23855 (70914) | 70914..71396 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| KIM92_RS23860 (71389) | 71389..71436 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| KIM92_RS23865 (71427) | 71427..71678 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| KIM92_RS23870 (71695) | 71695..71952 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| KIM92_RS23875 (72236) | 72236..72385 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (72429) | 72429..72490 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (72429) | 72429..72490 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (72429) | 72429..72490 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (72429) | 72429..72490 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| KIM92_RS23880 (72746) | 72746..72820 | - | 75 | Protein_66 | endonuclease | - |
| KIM92_RS23885 (73066) | 73066..73278 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| KIM92_RS23890 (73414) | 73414..73974 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| KIM92_RS23895 (74077) | 74077..74937 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| KIM92_RS23900 (74996) | 74996..75742 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| KIM92_RS23905 (75762) | 75762..81032 | - | 5271 | WP_000986963.1 | Multifunctional conjugation protein TraI | Relaxase |
| KIM92_RS23910 (81114) | 81114..81341 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| KIM92_RS23915 (81341) | 81341..81739 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KIM92_RS23920 (81748) | 81748..83901 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| KIM92_RS23925 (84154) | 84154..84864 | - | 711 | WP_230133085.1 | conjugal transfer complement resistance protein TraT | - |
| KIM92_RS23930 (84917) | 84917..85414 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| KIM92_RS23935 (85430) | 85430..88252 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KIM92_RS23940 (88249) | 88249..89622 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| KIM92_RS23945 (89622) | 89622..90002 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| KIM92_RS23950 (89989) | 89989..90330 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| KIM92_RS23955 (90260) | 90260..90805 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KIM92_RS23960 (90792) | 90792..91076 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KIM92_RS23965 (91157) | 91157..91471 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| KIM92_RS23970 (91473) | 91473..91820 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| KIM92_RS23975 (91836) | 91836..92579 | - | 744 | WP_001030377.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KIM92_RS23980 (92572) | 92572..92829 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| KIM92_RS23985 (92856) | 92856..94664 | - | 1809 | WP_000821838.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KIM92_RS23990 (94661) | 94661..95299 | - | 639 | WP_000777695.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KIM92_RS23995 (95308) | 95308..96300 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| KIM92_RS24000 (96297) | 96297..96929 | - | 633 | WP_001203717.1 | type-F conjugative transfer system protein TraW | - |
| KIM92_RS24005 (96926) | 96926..97312 | - | 387 | WP_000099691.1 | type-F conjugative transfer system protein TrbI | - |
| KIM92_RS24010 (97309) | 97309..99936 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| KIM92_RS24015 (100096) | 100096..100317 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KIM92_RS24020 (100452) | 100452..100967 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KIM92_RS24025 (100964) | 100964..101215 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| KIM92_RS24030 (101227) | 101227..101424 | - | 198 | WP_024179215.1 | conjugal transfer protein TrbD | - |
| KIM92_RS24035 (101411) | 101411..102001 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KIM92_RS24040 (101991) | 101991..103418 | - | 1428 | WP_000146676.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KIM92_RS24045 (103418) | 103418..104146 | - | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| KIM92_RS24050 (104133) | 104133..104699 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| KIM92_RS24055 (104721) | 104721..105032 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KIM92_RS24060 (105047) | 105047..105412 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| KIM92_RS24065 (105455) | 105455..105670 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| KIM92_RS24070 (105806) | 105806..106453 | - | 648 | WP_134241082.1 | conjugal transfer transcriptional regulator TraJ | - |
| KIM92_RS24075 (106645) | 106645..107028 | - | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KIM92_RS24080 (107380) | 107380..107970 | + | 591 | WP_166494936.1 | hypothetical protein | VF |
| KIM92_RS24085 (108265) | 108265..109086 | - | 822 | WP_001234475.1 | DUF932 domain-containing protein | - |
| KIM92_RS24090 (109205) | 109205..109492 | - | 288 | WP_000107546.1 | hypothetical protein | - |
| KIM92_RS24095 (109517) | 109517..109723 | - | 207 | WP_000547965.1 | hypothetical protein | - |
| KIM92_RS24100 (109793) | 109793..110089 | + | 297 | Protein_110 | hypothetical protein | - |
| KIM92_RS24105 (110390) | 110390..110515 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KIM92_RS24110 (110457) | 110457..110606 | - | 150 | Protein_112 | DUF5431 family protein | - |
| - (110613) | 110613..110811 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (110613) | 110613..110811 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (110613) | 110613..110811 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (110613) | 110613..110811 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| KIM92_RS24115 (110780) | 110780..111542 | - | 763 | Protein_113 | plasmid SOS inhibition protein A | - |
| KIM92_RS24120 (111539) | 111539..111973 | - | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| KIM92_RS24125 (112028) | 112028..113986 | - | 1959 | WP_029487628.1 | ParB/RepB/Spo0J family partition protein | - |
| KIM92_RS24130 (114052) | 114052..114285 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| KIM92_RS24135 (114342) | 114342..114881 | - | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| KIM92_RS24140 (115199) | 115199..115708 | + | 510 | WP_071600123.1 | hypothetical protein | - |
| KIM92_RS24145 (115678) | 115678..115869 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| KIM92_RS24150 (115866) | 115866..116288 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| KIM92_RS24155 (116335) | 116335..116760 | - | 426 | WP_001198918.1 | antirestriction protein | - |
| KIM92_RS24160 (117173) | 117173..117949 | - | 777 | WP_001005035.1 | hypothetical protein | - |
| KIM92_RS24165 (117995) | 117995..118549 | - | 555 | WP_077248347.1 | DUF1380 family protein | - |
| KIM92_RS24170 (118443) | 118443..118664 | - | 222 | WP_001104870.1 | hypothetical protein | - |
| KIM92_RS24175 (118665) | 118665..119348 | - | 684 | WP_000085939.1 | DNA methylase | - |
| KIM92_RS24180 (119425) | 119425..119730 | - | 306 | WP_010891292.1 | hypothetical protein | - |
| KIM92_RS24185 (119734) | 119734..120635 | - | 902 | Protein_127 | DUF1281 domain-containing protein | - |
| KIM92_RS24190 (121545) | 121545..122516 | - | 972 | WP_000817035.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KIM92_RS24195 (122516) | 122516..123682 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| KIM92_RS24200 (124270) | 124270..125025 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| KIM92_RS24205 (125777) | 125777..126583 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| KIM92_RS24210 (126584) | 126584..126889 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| KIM92_RS24215 (126891) | 126891..127109 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| KIM92_RS24220 (127701) | 127701..128189 | + | 489 | WP_011254646.1 | hypothetical protein | - |
| KIM92_RS24225 (128223) | 128223..129356 | - | 1134 | WP_000545984.1 | DUF3800 domain-containing protein | - |
| KIM92_RS24230 (129523) | 129523..130296 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| KIM92_RS24235 (130309) | 130309..130809 | - | 501 | WP_000528932.1 | HEPN family nuclease | - |
| KIM92_RS24240 (131074) | 131074..131304 | + | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KIM92_RS24245 (131301) | 131301..131717 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KIM92_RS24250 (131762) | 131762..135556 | - | 3795 | WP_001144731.1 | hypothetical protein | - |
| KIM92_RS24255 (135937) | 135937..136167 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KIM92_RS24260 (136164) | 136164..136580 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KIM92_RS24265 (136655) | 136655..138220 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| KIM92_RS24270 (138205) | 138205..139227 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| KIM92_RS24280 (140558) | 140558..142759 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| KIM92_RS24285 (142785) | 142785..144118 | - | 1334 | Protein_147 | L-lysine N6-monooxygenase | VF |
| KIM92_RS24290 (144115) | 144115..145857 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| KIM92_RS24295 (145857) | 145857..146804 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| KIM92_RS24300 (146805) | 146805..148529 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| KIM92_RS24305 (148665) | 148665..149858 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| KIM92_RS24310 (150238) | 150238..150618 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| KIM92_RS24315 (150959) | 150959..151372 | - | 414 | Protein_153 | phosphopyruvate hydratase | - |
| KIM92_RS24320 (151861) | 151861..152718 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| KIM92_RS24325 (152715) | 152715..153572 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| KIM92_RS24330 (153569) | 153569..154396 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| KIM92_RS24335 (154396) | 154396..155310 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| KIM92_RS24340 (155666) | 155666..156363 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| KIM92_RS24345 (156543) | 156543..157056 | - | 514 | Protein_159 | DUF4113 domain-containing protein | - |
| KIM92_RS24350 (157117) | 157117..157221 | - | 105 | Protein_160 | AAA family ATPase | - |
| KIM92_RS24355 (157223) | 157223..157546 | - | 324 | Protein_161 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|