MGE detailed information
MGE type: Conjugative plasmid MGE length: 129627 bp
Accession: NZ_CP026724 Location: 1..129627 Organism: Escherichia coli strain 266917_2 Replicon: plasmid p266917_2_01
Accession: NZ_CP026724 Location: 1..129627 Organism: Escherichia coli strain 266917_2 Replicon: plasmid p266917_2_01
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C4R22_RS28680 () | 1301..2041 | - | 741 | WP_001066940.1 | tyrosine-type recombinase/integrase | - |
| C4R22_RS28695 () | 2689..2994 | - | 306 | WP_089643027.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| C4R22_RS28705 () | 3487..4656 | + | 1170 | WP_001403369.1 | hypothetical protein | - |
| C4R22_RS28710 () | 4689..4817 | + | 129 | Protein_4 | IS481 family transposase | - |
| C4R22_RS28715 () | 4852..5145 | - | 294 | WP_001105065.1 | hypothetical protein | - |
| C4R22_RS28720 () | 5251..5526 | - | 276 | WP_000421273.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C4R22_RS28725 () | 5526..5810 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| C4R22_RS28730 () | 6415..7167 | + | 753 | WP_001403368.1 | IclR family transcriptional regulator | - |
| C4R22_RS28735 () | 7213..8178 | - | 966 | WP_023063778.1 | 2-keto-3-deoxygluconate transporter | - |
| C4R22_RS28740 () | 8211..8591 | - | 381 | WP_001403366.1 | Rid family detoxifying hydrolase | - |
| C4R22_RS28745 () | 8616..9506 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| C4R22_RS28750 () | 9859..10425 | + | 567 | Protein_12 | zinc-binding dehydrogenase | - |
| C4R22_RS28755 () | 10556..11434 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| C4R22_RS28760 () | 11424..12311 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| C4R22_RS28765 () | 12322..13146 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| C4R22_RS28770 () | 13152..14225 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| C4R22_RS28775 () | 14218..15528 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| C4R22_RS28780 () | 15587..15895 | - | 309 | Protein_18 | IS4 family transposase ISEc13 | Transposase |
| C4R22_RS28785 () | 15972..16187 | - | 216 | Protein_19 | Tn3 family transposase | - |
| C4R22_RS28790 () | 16242..17455 | + | 1214 | WP_199773178.1 | IS3 family transposase IS629 | Transposase |
| C4R22_RS28800 () | 17504..17923 | - | 420 | WP_024210387.1 | IS66 family transposase IS682 | Transposase |
| C4R22_RS28805 () | 18232..19782 | - | 1551 | WP_000127288.1 | gluconate permease | - |
| C4R22_RS28810 () | 19821..20819 | - | 999 | WP_000803224.1 | 4-hydroxythreonine-4-phosphate dehydrogenase PdxA | - |
| C4R22_RS28815 () | 20842..22143 | - | 1302 | WP_023063782.1 | four-carbon acid sugar kinase family protein | - |
| C4R22_RS28820 () | 22176..22883 | - | 708 | WP_002431139.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| C4R22_RS28825 () | 23035..24033 | + | 999 | WP_023063783.1 | Arabinose 5-phosphate isomerase KdsD | VF |
| C4R22_RS28830 () | 24109..25008 | - | 900 | Protein_27 | IS3 family transposase ISCfr6 | Transposase |
| C4R22_RS28835 () | 25079..26230 | + | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| C4R22_RS28840 () | 26243..26545 | - | 303 | Protein_29 | IS3 family transposase ISEc31 | Transposase |
| C4R22_RS28845 () | 26590..27449 | - | 860 | Protein_30 | IS3 family transposase IS629 | Transposase |
| C4R22_RS28850 () | 27923..29101 | + | 1179 | WP_001403462.1 | pyridoxal phosphate-dependent aminotransferase | - |
| C4R22_RS28855 () | 29094..30545 | + | 1452 | WP_001403463.1 | Na+/H+ antiporter NhaC | - |
| C4R22_RS28860 () | 30620..30753 | - | 134 | Protein_33 | phosphate-starvation-inducible protein PsiE | - |
| C4R22_RS28865 () | 30802..32421 | - | 1620 | Protein_34 | ISL3 family transposase ISEc38 | Transposase |
| C4R22_RS28870 () | 32518..33025 | + | 508 | Protein_35 | IS3 family transposase IS2 | Transposase |
| C4R22_RS28875 () | 33101..33280 | + | 180 | Protein_36 | polysaccharide deacetylase family protein | - |
| C4R22_RS28880 () | 33287..33667 | - | 381 | WP_032269702.1 | aspartate 1-decarboxylase | - |
| C4R22_RS28890 () | 33940..34071 | + | 132 | Protein_38 | Rpn family recombination-promoting nuclease/putative transposase | - |
| C4R22_RS28895 () | 34269..35663 | + | 1395 | WP_001402894.1 | MHS family MFS transporter | - |
| C4R22_RS28900 () | 35769..36800 | + | 1032 | WP_001402895.1 | LacI family transcriptional regulator | - |
| C4R22_RS28905 () | 36775..37794 | + | 1020 | WP_024200979.1 | nucleoside hydrolase | - |
| C4R22_RS28910 () | 37858..38571 | + | 714 | WP_032269703.1 | Protein SapB | VF |
| C4R22_RS28915 () | 38728..38967 | - | 240 | Protein_43 | IS4 family transposase | - |
| C4R22_RS28920 () | 39260..40282 | - | 1023 | WP_089643065.1 | IS110 family transposase IS1618 | Transposase |
| C4R22_RS28925 () | 40442..40924 | - | 483 | WP_001402899.1 | hypothetical protein | - |
| C4R22_RS28930 () | 41041..41880 | - | 840 | WP_001402900.1 | 3'-5' exonuclease | - |
| C4R22_RS28935 () | 41926..42207 | - | 282 | WP_001402901.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C4R22_RS28940 () | 42204..42473 | - | 270 | WP_000079941.1 | hypothetical protein | Antitoxin Detail |
| C4R22_RS28955 () | 43390..44247 | - | 858 | WP_000130641.1 | incFII family plasmid replication initiator RepA | - |
| C4R22_RS28960 () | 44240..44314 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| C4R22_RS31930 () | 44311..44445 | - | 135 | Protein_51 | protein CopA/IncA | - |
| C4R22_RS28970 () | 44552..44806 | - | 255 | WP_089643063.1 | replication regulatory protein RepA | - |
| C4R22_RS28975 () | 45103..45237 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 45283..45334 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| - () | 45283..45334 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| - () | 45283..45334 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| - () | 45283..45334 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| C4R22_RS28980 () | 45301..45587 | - | 287 | Protein_54 | DUF2726 domain-containing protein | - |
| C4R22_RS28990 () | 46099..46311 | - | 213 | WP_104858475.1 | ANR family transcriptional regulator | - |
| C4R22_RS28995 () | 46443..47003 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| C4R22_RS29000 () | 47058..47804 | - | 747 | WP_032188604.1 | conjugal transfer pilus acetylase TraX | - |
| C4R22_RS29005 () | 47824..53094 | - | 5271 | WP_096837149.1 | Multifunctional conjugation protein TraI | Relaxase |
| C4R22_RS29010 () | 53094..55328 | - | 2235 | WP_104858476.1 | type IV conjugative transfer system coupling protein TraD | - |
| C4R22_RS29015 () | 55610..56089 | - | 480 | WP_001473214.1 | hypothetical protein | - |
| C4R22_RS29020 () | 56293..57024 | - | 732 | WP_001403424.1 | complement resistance protein TraT | - |
| C4R22_RS29025 () | 57073..57552 | - | 480 | WP_011666498.1 | TraS protein | - |
| C4R22_RS29030 () | 57574..60396 | - | 2823 | WP_089643034.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C4R22_RS29035 () | 60393..61766 | - | 1374 | WP_001403427.1 | conjugal transfer protein TraH | - |
| C4R22_RS29040 () | 61753..62178 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| C4R22_RS29045 () | 62126..62467 | - | 342 | WP_122986665.1 | P-type conjugative transfer protein TrbJ | - |
| C4R22_RS29050 () | 62397..62942 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C4R22_RS29055 () | 62929..63213 | - | 285 | WP_000623730.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C4R22_RS29060 () | 63340..63678 | - | 339 | WP_001287901.1 | conjugal transfer protein TrbA | - |
| C4R22_RS29065 () | 63694..64437 | - | 744 | WP_001403429.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C4R22_RS29070 () | 64430..64687 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| C4R22_RS29075 () | 64714..66564 | - | 1851 | WP_104858477.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C4R22_RS29080 () | 66561..67199 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C4R22_RS29085 () | 67208..67513 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| C4R22_RS29090 () | 67543..68535 | - | 993 | WP_032277446.1 | conjugal transfer pilus assembly protein TraU | - |
| C4R22_RS29095 () | 68532..69164 | - | 633 | WP_032277445.1 | type-F conjugative transfer system protein TraW | - |
| C4R22_RS29100 () | 69161..69547 | - | 387 | WP_032277443.1 | type-F conjugative transfer system protein TrbI | - |
| C4R22_RS29105 () | 69544..72171 | - | 2628 | WP_001505126.1 | type IV secretion system protein TraC | - |
| C4R22_RS29110 () | 72331..72552 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| C4R22_RS29115 () | 72687..73202 | - | 516 | WP_032277441.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C4R22_RS29120 () | 73202..73561 | - | 360 | WP_001617876.1 | conjugal transfer protein TrbD | - |
| C4R22_RS29125 () | 73500..74087 | - | 588 | WP_089643040.1 | conjugal transfer protein TraP | - |
| C4R22_RS29130 () | 74056..75507 | - | 1452 | WP_000146647.1 | conjugal transfer protein TraB | - |
| C4R22_RS29135 () | 75507..76211 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| C4R22_RS29140 () | 76222..76788 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| C4R22_RS29145 () | 76810..77121 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| C4R22_RS29150 () | 77126..77488 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| C4R22_RS29155 () | 77522..77749 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| C4R22_RS29160 () | 77837..78529 | - | 693 | WP_104858478.1 | PAS domain-containing protein | - |
| C4R22_RS29165 () | 78723..79106 | - | 384 | WP_023063829.1 | relaxosome protein TraM | - |
| C4R22_RS29170 () | 79449..80039 | + | 591 | WP_167575169.1 | hypothetical protein | VF |
| C4R22_RS29180 () | 80334..81155 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| C4R22_RS29185 () | 81274..81561 | - | 288 | WP_000107526.1 | hypothetical protein | - |
| C4R22_RS31935 () | 81862..82111 | + | 250 | Protein_94 | hypothetical protein | - |
| C4R22_RS29205 () | 82414..82572 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 82616..82840 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 82616..82840 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 82616..82840 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 82616..82840 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| C4R22_RS31685 () | 82652..82831 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| C4R22_RS29210 () | 82852..83571 | - | 720 | WP_001403352.1 | plasmid SOS inhibition protein A | - |
| C4R22_RS29215 () | 83568..84002 | - | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| C4R22_RS29220 () | 84057..84359 | - | 303 | Protein_99 | hypothetical protein | - |
| C4R22_RS29225 () | 84439..84636 | + | 198 | Protein_100 | IS3 family transposase ISCARN101 | Transposase |
| C4R22_RS31690 () | 84691..84849 | + | 159 | Protein_101 | IS3 family transposase ISCARN101 | Transposase |
| C4R22_RS29235 () | 84865..85562 | - | 698 | Protein_102 | IS1 family transposase IS1X2 | Transposase |
| C4R22_RS29240 () | 85671..86882 | - | 1212 | WP_001390768.1 | dispersin export-associated protein AatD | - |
| C4R22_RS29245 () | 86894..87523 | - | 630 | WP_000621743.1 | dispersin export ABC transporter ATP-binding protein AatC | - |
| C4R22_RS29250 () | 87516..88337 | - | 822 | WP_033879863.1 | dispersin export-associated protein AatB | - |
| C4R22_RS29255 () | 88234..89472 | - | 1239 | WP_044691032.1 | dispersin export ABC transporter outer membrane protein AatA | - |
| C4R22_RS29260 () | 89469..90599 | - | 1131 | WP_089643057.1 | dispersin export ABC transporter permease subunit AatP | - |
| C4R22_RS29265 () | 90979..91149 | + | 171 | Protein_108 | IS3 family transposase IS1203 | Transposase |
| C4R22_RS29270 () | 91370..91606 | + | 237 | WP_000239755.1 | IS66 family transposase IS682 | Transposase |
| C4R22_RS29275 () | 91641..93367 | - | 1727 | Protein_110 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| C4R22_RS29290 () | 93684..94664 | - | 981 | Protein_111 | IS630 family transposase | - |
| C4R22_RS29295 () | 94882..95082 | - | 201 | WP_024210368.1 | AggR-activated transcriptional regulator Aar | - |
| C4R22_RS29300 () | 95188..95503 | - | 316 | Protein_113 | hypothetical protein | - |
| C4R22_RS31695 () | 95813..96163 | + | 351 | WP_000721276.1 | hypothetical protein | VF |
| C4R22_RS29305 () | 96271..96467 | - | 197 | Protein_115 | integrase core domain-containing protein | - |
| C4R22_RS29310 () | 96463..96788 | + | 326 | Protein_116 | IS3 family transposase | - |
| C4R22_RS29315 () | 97004..97801 | + | 798 | WP_000769457.1 | CFA/I fimbrial subunit D | VF |
| C4R22_RS29320 () | 97902..98096 | + | 195 | Protein_118 | IS1 family transposase ISEc30 | Transposase |
| C4R22_RS29325 () | 98085..98273 | + | 189 | Protein_119 | IS1 family transposase ISEc30 | Transposase |
| C4R22_RS29330 () | 98549..99552 | - | 1004 | Protein_120 | IS110 family transposase ISPlu13 | Transposase |
| C4R22_RS29345 () | 99929..100118 | + | 190 | Protein_121 | IS200/IS605 family transposase | - |
| C4R22_RS29350 () | 100117..100480 | + | 364 | Protein_122 | zinc ABC transporter substrate-binding protein | - |
| C4R22_RS29355 () | 100539..100905 | + | 367 | Protein_123 | IS3 family transposase IS1203 | Transposase |
| C4R22_RS31940 () | 101138..101290 | + | 153 | WP_000565591.1 | hypothetical protein | - |
| C4R22_RS29360 () | 101793..102332 | - | 540 | WP_001387337.1 | isopentenyl-diphosphate Delta-isomerase | - |
| C4R22_RS29365 () | 102336..103364 | - | 1029 | WP_000869859.1 | class 1 isoprenoid biosynthesis enzyme | - |
| C4R22_RS29370 () | 103593..103766 | - | 174 | Protein_127 | integrase core domain-containing protein | - |
| C4R22_RS29380 () | 104015..104272 | + | 258 | Protein_128 | IS3 family transposase IS911 | Transposase |
| C4R22_RS29385 () | 104340..105491 | + | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| C4R22_RS29390 () | 105501..106406 | + | 906 | Protein_130 | IS3 family transposase IS911 | Transposase |
| C4R22_RS29395 () | 106659..107174 | - | 516 | WP_001573188.1 | hypothetical protein | VF |
| C4R22_RS29400 () | 107275..107712 | - | 438 | WP_001573189.1 | Protein AggB | VF |
| C4R22_RS29405 () | 107726..110254 | - | 2529 | WP_104858480.1 | F1 capsule-anchoring protein | VF |
| C4R22_RS29410 () | 110268..111026 | - | 759 | WP_089643025.1 | Chaperone protein caf1M | VF |
| C4R22_RS31945 () | 111468..111702 | + | 235 | Protein_135 | hypothetical protein | - |
| C4R22_RS29430 () | 111683..111862 | + | 180 | WP_001390505.1 | IS91 family transposase ISSbo1 | Transposase |
| C4R22_RS29435 () | 111869..112435 | - | 567 | WP_032154304.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C4R22_RS31950 () | 112440..112565 | - | 126 | Protein_138 | 3'-5' exonuclease | - |
| C4R22_RS29445 () | 112567..112944 | + | 378 | WP_000457137.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| C4R22_RS29450 () | 112944..114218 | + | 1275 | Protein_140 | Y-family DNA polymerase | - |
| C4R22_RS29460 () | 114220..114636 | - | 417 | WP_001278815.1 | plasmid partitioning/stability family protein | - |
| C4R22_RS29465 () | 114629..115609 | - | 981 | WP_001403375.1 | plasmid segregation protein ParM | - |
| C4R22_RS29470 () | 116022..116330 | - | 309 | WP_000030204.1 | molecular chaperone GroEL | - |
| C4R22_RS29475 () | 116417..117061 | - | 645 | WP_001144036.1 | ParA family protein | - |
| C4R22_RS29480 () | 117240..118046 | - | 807 | WP_024210383.1 | site-specific integrase | - |
| C4R22_RS29485 () | 118047..118352 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C4R22_RS29490 () | 118354..118572 | - | 219 | WP_000813639.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C4R22_RS29500 () | 119390..119680 | - | 291 | WP_000648897.1 | hypothetical protein | - |
| C4R22_RS29505 () | 119680..120804 | - | 1125 | WP_000386705.1 | DUF4238 domain-containing protein | - |
| C4R22_RS29510 () | 120839..122431 | - | 1593 | WP_001350003.1 | hypothetical protein | - |
| C4R22_RS29515 () | 122653..123411 | - | 759 | WP_023063772.1 | hypothetical protein | - |
| C4R22_RS29520 () | 123423..123914 | - | 492 | WP_000528930.1 | hypothetical protein | - |
| C4R22_RS29525 () | 124288..126909 | + | 2622 | WP_023063774.1 | ABC transporter | - |
| C4R22_RS29530 () | 127108..127338 | + | 231 | WP_001261274.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| C4R22_RS29535 () | 127427..127702 | + | 276 | WP_001403920.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| C4R22_RS31700 () | 127707..127924 | - | 218 | Protein_156 | transposase | - |
| C4R22_RS29540 () | 127925..128455 | - | 531 | WP_023063775.1 | GNAT family N-acetyltransferase | - |
| C4R22_RS29545 () | 128459..128728 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|