MGE detailed information
MGE type: Conjugative plasmid MGE length: 129195 bp
Accession: NZ_CP025574 Location: 1..129195 Organism: Escherichia coli strain E-1246 Replicon: plasmid pE1246_1
Accession: NZ_CP025574 Location: 1..129195 Organism: Escherichia coli strain E-1246 Replicon: plasmid pE1246_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CY655_RS26855 () | 241..1260 | - | 1020 | WP_024200979.1 | nucleoside hydrolase | - |
| CY655_RS26860 () | 1235..2266 | - | 1032 | WP_001402895.1 | LacI family transcriptional regulator | - |
| CY655_RS26865 () | 2372..3766 | - | 1395 | WP_001402894.1 | MHS family MFS transporter | - |
| CY655_RS26870 () | 3964..4095 | - | 132 | Protein_4 | Rpn family recombination-promoting nuclease/putative transposase | - |
| CY655_RS26875 () | 4368..4748 | + | 381 | WP_032269702.1 | aspartate 1-decarboxylase | - |
| CY655_RS26880 () | 4755..4934 | - | 180 | Protein_6 | polysaccharide deacetylase family protein | - |
| CY655_RS26885 () | 5010..5517 | - | 508 | Protein_7 | DDE-type integrase/transposase/recombinase | - |
| CY655_RS26890 () | 5614..7233 | + | 1620 | WP_072003777.1 | ISL3 family transposase | - |
| CY655_RS26895 () | 7282..7415 | + | 134 | Protein_9 | phosphate-starvation-inducible protein PsiE | - |
| CY655_RS26900 () | 7490..8941 | - | 1452 | WP_001403463.1 | Na+/H+ antiporter NhaC | - |
| CY655_RS26905 () | 8934..10112 | - | 1179 | WP_032284172.1 | pyridoxal phosphate-dependent aminotransferase | - |
| CY655_RS26920 () | 11618..11824 | + | 207 | Protein_13 | Tn3 family transposase | - |
| CY655_RS26925 () | 11901..12209 | + | 309 | Protein_14 | IS4 family transposase | - |
| CY655_RS26930 () | 12268..13578 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| CY655_RS26935 () | 13571..14644 | - | 1074 | WP_000950177.1 | ABC transporter ATP-binding protein | - |
| CY655_RS26940 () | 14650..15474 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| CY655_RS26945 () | 15485..16372 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| CY655_RS26950 () | 16362..17240 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| CY655_RS26955 () | 17371..17937 | - | 567 | Protein_20 | zinc-binding dehydrogenase | - |
| CY655_RS26960 () | 18290..19180 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| CY655_RS26965 () | 19205..19585 | + | 381 | WP_001403366.1 | Rid family detoxifying hydrolase | - |
| CY655_RS26970 () | 19618..20583 | + | 966 | WP_023063778.1 | 2-keto-3-deoxygluconate transporter | - |
| CY655_RS26975 () | 20629..21381 | - | 753 | WP_001403368.1 | IclR family transcriptional regulator | - |
| CY655_RS26980 () | 21986..22270 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| CY655_RS26985 () | 22270..22545 | + | 276 | WP_032250674.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| CY655_RS26990 () | 22651..22944 | + | 294 | WP_032284273.1 | hypothetical protein | - |
| CY655_RS26995 () | 22979..23107 | - | 129 | Protein_28 | IS481 family transposase | - |
| CY655_RS27000 () | 23140..24309 | - | 1170 | WP_032284272.1 | hypothetical protein | - |
| CY655_RS27010 () | 24802..24972 | + | 171 | WP_096790846.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| CY655_RS27020 () | 25225..25386 | + | 162 | WP_001440647.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CY655_RS27025 () | 25453..25635 | + | 183 | WP_050488504.1 | hypothetical protein | - |
| CY655_RS27030 () | 25756..26496 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| CY655_RS27035 () | 26775..27752 | - | 978 | WP_000361615.1 | RepB family plasmid replication initiator protein | - |
| CY655_RS27045 () | 28765..29190 | + | 426 | WP_000422741.1 | IS66 family insertion sequence hypothetical protein | - |
| CY655_RS27050 () | 29187..29537 | + | 351 | Protein_36 | IS66 family insertion sequence element accessory protein TnpB | - |
| CY655_RS27055 () | 29568..31125 | + | 1558 | Protein_37 | IS66-like element ISEc23 family transposase | - |
| CY655_RS27060 () | 31349..33487 | + | 2139 | WP_032269946.1 | ATPase AAA | - |
| CY655_RS27065 () | 33657..34058 | - | 402 | WP_001441071.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| CY655_RS27070 () | 34082..34312 | - | 231 | WP_001261288.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| CY655_RS27080 () | 34906..35124 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| CY655_RS27085 () | 35126..35431 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| CY655_RS27090 () | 35432..36241 | + | 810 | WP_000016979.1 | site-specific integrase | - |
| CY655_RS27095 () | 36379..36654 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| CY655_RS27100 () | 36648..37292 | - | 645 | WP_000633911.1 | AAA family ATPase | - |
| CY655_RS27105 () | 37521..38492 | + | 972 | WP_001103689.1 | hypothetical protein | - |
| CY655_RS27110 () | 38497..38889 | + | 393 | WP_000340832.1 | plasmid partitioning/stability family protein | - |
| CY655_RS27115 () | 38921..40049 | - | 1129 | Protein_48 | translesion error-prone DNA polymerase V subunit UmuC | - |
| CY655_RS27120 () | 40049..40486 | - | 438 | WP_000109070.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CY655_RS27125 () | 40483..40731 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| CY655_RS27135 () | 41006..41908 | + | 903 | WP_077513943.1 | DUF1281 domain-containing protein | - |
| CY655_RS27140 () | 41980..42643 | - | 664 | Protein_52 | IS3 family transposase | - |
| CY655_RS27145 () | 43015..43767 | + | 753 | WP_032269683.1 | aggregative adherence fimbria 3 chaperone Agg3D | - |
| CY655_RS27150 () | 43822..46371 | + | 2550 | WP_033868841.1 | aggregative adherence fimbria 3 usher protein Agg3C | - |
| CY655_RS27155 () | 46385..46825 | + | 441 | WP_001390764.1 | aggregative adherence fimbria 3 minor subunit Agg3B | - |
| CY655_RS27970 () | 47000..47515 | + | 516 | WP_139453519.1 | aggregative adherence fimbria V major subunit Agg5A | - |
| CY655_RS27975 () | 47596..47754 | + | 159 | Protein_57 | IS256 family transposase | - |
| CY655_RS27175 () | 47964..48929 | + | 966 | Protein_58 | IS3 family transposase | - |
| CY655_RS27180 () | 49127..50155 | + | 1029 | WP_000869859.1 | class 1 isoprenoid biosynthesis enzyme | - |
| CY655_RS27185 () | 50159..50698 | + | 540 | WP_001387337.1 | isopentenyl-diphosphate Delta-isomerase | - |
| CY655_RS27980 () | 51201..51353 | - | 153 | WP_000565591.1 | hypothetical protein | - |
| CY655_RS27190 () | 51586..51952 | - | 367 | Protein_62 | transposase | - |
| CY655_RS27195 () | 52011..52374 | - | 364 | Protein_63 | zinc ABC transporter substrate-binding protein | - |
| CY655_RS27200 () | 52373..52561 | - | 189 | Protein_64 | IS200/IS605 family transposase | - |
| CY655_RS27210 () | 52940..53943 | + | 1004 | Protein_65 | IS110 family transposase | - |
| CY655_RS27215 () | 54219..54407 | - | 189 | Protein_66 | transposase | - |
| CY655_RS27220 () | 54396..54590 | - | 195 | Protein_67 | IS1 family transposase | - |
| CY655_RS27230 () | 54691..55488 | - | 798 | WP_000769457.1 | aggregative adherence transcriptional regulator AggR | - |
| CY655_RS27235 () | 55703..56028 | - | 326 | Protein_69 | IS3 family transposase | - |
| CY655_RS27240 () | 56024..56220 | + | 197 | Protein_70 | integrase core domain-containing protein | - |
| CY655_RS27245 () | 56328..56678 | - | 351 | WP_000721276.1 | dispersin Aap | - |
| CY655_RS27250 () | 56988..57303 | + | 316 | Protein_72 | hypothetical protein | - |
| CY655_RS27255 () | 57409..57609 | + | 201 | WP_000643555.1 | AggR-activated transcriptional regulator Aar | - |
| CY655_RS27260 () | 57827..58820 | + | 994 | Protein_74 | IS630 family transposase | - |
| CY655_RS27985 () | 59137..60863 | + | 1727 | Protein_75 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| CY655_RS27280 () | 60898..61134 | - | 237 | WP_000239755.1 | transposase | - |
| CY655_RS27290 () | 61355..61525 | - | 171 | Protein_77 | transposase | - |
| CY655_RS27295 () | 61905..63035 | + | 1131 | WP_000209218.1 | dispersin export ABC transporter permease subunit AatP | - |
| CY655_RS27300 () | 63032..64270 | + | 1239 | WP_001216022.1 | dispersin export ABC transporter outer membrane protein AatA | - |
| CY655_RS27305 () | 64167..64988 | + | 822 | WP_002431107.1 | dispersin export-associated protein AatB | - |
| CY655_RS27310 () | 64981..65610 | + | 630 | WP_000621743.1 | dispersin export ABC transporter ATP-binding protein AatC | - |
| CY655_RS27315 () | 65622..66833 | + | 1212 | WP_001390768.1 | dispersin export-associated protein AatD | - |
| CY655_RS27325 () | 67683..67889 | + | 207 | Protein_83 | transposase | - |
| CY655_RS27330 () | 68401..69753 | + | 1353 | Protein_84 | group II intron reverse transcriptase/maturase | - |
| CY655_RS27335 () | 69962..70363 | + | 402 | WP_000085189.1 | hypothetical protein | - |
| CY655_RS27340 () | 70463..71020 | - | 558 | WP_001235702.1 | recombinase family protein | - |
| CY655_RS27990 () | 71598..71753 | + | 156 | WP_000074142.1 | hypothetical protein | - |
| CY655_RS27350 () | 71802..72794 | + | 993 | WP_096790811.1 | hypothetical protein | - |
| CY655_RS27355 () | 73011..73688 | + | 678 | WP_001088238.1 | IS66 family insertion sequence hypothetical protein | - |
| CY655_RS27360 () | 73685..74032 | + | 348 | WP_000631721.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| CY655_RS27365 () | 74052..75608 | + | 1557 | Protein_91 | IS66 family transposase | - |
| CY655_RS27995 () | 75675..75929 | - | 255 | Protein_92 | hypothetical protein | - |
| CY655_RS27380 () | 76444..76674 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| CY655_RS27385 () | 76726..78087 | + | 1362 | WP_000170670.1 | DUF3560 domain-containing protein | - |
| CY655_RS27390 () | 78134..78697 | + | 564 | WP_001403466.1 | class I SAM-dependent methyltransferase | - |
| CY655_RS27415 () | 79570..80091 | + | 522 | WP_000290849.1 | single-stranded DNA-binding protein | - |
| CY655_RS27420 () | 80147..80380 | + | 234 | WP_000005970.1 | DUF905 domain-containing protein | - |
| CY655_RS27425 () | 80439..82397 | + | 1959 | Protein_98 | ParB/RepB/Spo0J family partition protein | - |
| CY655_RS27430 () | 82452..82886 | + | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| CY655_RS27435 () | 82883..83602 | + | 720 | WP_001403352.1 | plasmid SOS inhibition protein A | - |
| - () | 83614..83838 | + | 225 | NuclAT_0 | - | - |
| - () | 83614..83838 | + | 225 | NuclAT_0 | - | - |
| - () | 83614..83838 | + | 225 | NuclAT_0 | - | - |
| - () | 83614..83838 | + | 225 | NuclAT_0 | - | - |
| CY655_RS28000 () | 83623..83802 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| CY655_RS27440 () | 83882..84040 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| CY655_RS28005 () | 84341..84572 | - | 232 | Protein_103 | hypothetical protein | - |
| CY655_RS27455 () | 84890..85177 | + | 288 | WP_000107526.1 | hypothetical protein | - |
| CY655_RS27460 () | 85296..86117 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| CY655_RS27470 () | 86412..87014 | - | 603 | WP_023908348.1 | transglycosylase SLT domain-containing protein | - |
| CY655_RS27475 () | 87336..87719 | + | 384 | WP_001151538.1 | relaxosome protein TraM | - |
| CY655_RS27480 () | 87906..88595 | + | 690 | WP_032173224.1 | conjugal transfer transcriptional regulator TraJ | - |
| CY655_RS27485 () | 88694..89089 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| CY655_RS27490 () | 89122..89487 | + | 366 | WP_001098989.1 | type IV conjugative transfer system pilin TraA | - |
| CY655_RS27495 () | 89502..89813 | + | 312 | WP_000012116.1 | type IV conjugative transfer system protein TraL | - |
| CY655_RS27500 () | 89835..90401 | + | 567 | WP_032261454.1 | type IV conjugative transfer system protein TraE | - |
| CY655_RS27505 () | 90388..91116 | + | 729 | WP_032179724.1 | type-F conjugative transfer system secretin TraK | - |
| CY655_RS27510 () | 91116..92567 | + | 1452 | WP_032269648.1 | conjugal transfer protein TraB | - |
| CY655_RS27515 () | 92536..93123 | + | 588 | WP_072003756.1 | conjugal transfer protein TraP | - |
| CY655_RS27520 () | 93110..93427 | + | 318 | WP_001057281.1 | DUF2689 domain-containing protein | - |
| CY655_RS27525 () | 93427..93942 | + | 516 | WP_001403433.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CY655_RS27530 () | 94077..94298 | + | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| CY655_RS27535 () | 94458..97085 | + | 2628 | WP_001064239.1 | type IV secretion system protein TraC | - |
| CY655_RS27540 () | 97082..97468 | + | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| CY655_RS27545 () | 97465..98097 | + | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| CY655_RS27550 () | 98094..99086 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| CY655_RS27555 () | 99116..99421 | + | 306 | WP_000224412.1 | hypothetical protein | - |
| CY655_RS27560 () | 99430..100068 | + | 639 | WP_001463034.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CY655_RS27565 () | 100065..100445 | + | 381 | WP_001462111.1 | hypothetical protein | - |
| CY655_RS27570 () | 100756..102543 | + | 1788 | WP_029976537.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CY655_RS27575 () | 102570..102827 | + | 258 | WP_000864319.1 | conjugal transfer protein TrbE | - |
| CY655_RS27580 () | 102820..103563 | + | 744 | WP_001462109.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CY655_RS27585 () | 103579..103917 | + | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| CY655_RS27590 () | 104044..104328 | + | 285 | WP_000623730.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CY655_RS27595 () | 104315..104860 | + | 546 | WP_000059832.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CY655_RS27600 () | 104790..105131 | + | 342 | WP_126716471.1 | P-type conjugative transfer protein TrbJ | - |
| CY655_RS27605 () | 105079..105504 | + | 426 | WP_072005451.1 | F-type conjugal transfer protein TrbF | - |
| CY655_RS27610 () | 105491..106864 | + | 1374 | WP_044692455.1 | conjugal transfer protein TraH | - |
| CY655_RS27615 () | 106861..109686 | + | 2826 | WP_029702178.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CY655_RS27620 () | 109683..110192 | + | 510 | WP_024168260.1 | conjugal transfer entry exclusion protein TraS | - |
| CY655_RS27625 () | 110206..110937 | + | 732 | WP_001734698.1 | complement resistance protein TraT | - |
| CY655_RS27630 () | 111140..111877 | + | 738 | WP_000199908.1 | hypothetical protein | - |
| CY655_RS27635 () | 111928..114153 | + | 2226 | WP_052935733.1 | type IV conjugative transfer system coupling protein TraD | - |
| CY655_RS27640 () | 114153..119423 | + | 5271 | WP_096790916.1 | conjugative transfer relaxase/helicase TraI | - |
| CY655_RS27645 () | 119443..120189 | + | 747 | WP_000205736.1 | conjugal transfer pilus acetylase TraX | - |
| CY655_RS27650 () | 120244..120804 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| CY655_RS27655 () | 120936..121148 | + | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| CY655_RS28010 () | 121660..121946 | + | 287 | Protein_144 | DUF2726 domain-containing protein | - |
| - () | 121913..121964 | - | 52 | NuclAT_1 | - | - |
| - () | 121913..121964 | - | 52 | NuclAT_1 | - | - |
| - () | 121913..121964 | - | 52 | NuclAT_1 | - | - |
| - () | 121913..121964 | - | 52 | NuclAT_1 | - | - |
| CY655_RS27670 () | 122017..122151 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| CY655_RS27675 () | 122424..122678 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| CY655_RS28015 () | 122784..122918 | + | 135 | Protein_147 | protein CopA/IncA | - |
| CY655_RS27685 () | 122915..122989 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| CY655_RS27690 () | 122982..123839 | + | 858 | WP_032284166.1 | incFII family plasmid replication initiator RepA | - |
| CY655_RS27705 () | 124757..125026 | + | 270 | WP_000079941.1 | hypothetical protein | Antitoxin Detail |
| CY655_RS27710 () | 125023..125304 | + | 282 | WP_001402901.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| CY655_RS27715 () | 125350..126189 | + | 840 | WP_032269705.1 | 3'-5' exonuclease | - |
| CY655_RS27720 () | 126306..126788 | + | 483 | WP_001402899.1 | hypothetical protein | - |
| CY655_RS27725 () | 126948..127970 | + | 1023 | WP_096790897.1 | IS110 family transposase | - |
| CY655_RS27730 () | 128263..128502 | + | 240 | Protein_155 | IS4 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|