MGE detailed information
MGE type: Conjugative plasmid MGE length: 124908 bp
Accession: NC_022996 Location: 1..124908 Organism: Escherichia coli Replicon: plasmid pO26-CRL-125
Accession: NC_022996 Location: 1..124908 Organism: Escherichia coli Replicon: plasmid pO26-CRL-125
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HTC40_RS00005 (D616_p108002) | 703..1575 | + | 873 | WP_000729440.1 | incFII family plasmid replication initiator RepA | - |
| HTC40_RS00010 (D616_p108004) | 2524..2775 | + | 252 | WP_001139207.1 | plasmid stabilization protein | Antitoxin Detail |
| HTC40_RS00015 (D616_p108005) | 2772..3059 | + | 288 | WP_000222775.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HTC40_RS00020 (D616_p108006) | 3069..3614 | + | 546 | WP_000926984.1 | hypothetical protein | - |
| HTC40_RS00025 (D616_p108008) | 4266..4868 | - | 603 | WP_000517694.1 | ProQ/FINO family protein | - |
| HTC40_RS00030 (D616_p108009) | 5222..5461 | + | 240 | Protein_5 | hypothetical protein | - |
| HTC40_RS00035 (D616_p108010) | 5496..8462 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HTC40_RS00040 (D616_p108011) | 8465..9025 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HTC40_RS00045 | 9151..9501 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HTC40_RS00050 (D616_p108014) | 9704..10717 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HTC40_RS00055 (D616_p108015) | 10873..11346 | + | 474 | WP_001317507.1 | Dihydrofolate reductase type 1 | ARG |
| HTC40_RS00060 (D616_p108016) | 11498..12202 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HTC40_RS00065 (D616_p108017) | 12266..12604 | + | 339 | Protein_12 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HTC40_RS00070 (D616_p108018) | 12787..13647 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HTC40_RS00075 (D616_p108019) | 13794..14075 | + | 282 | Protein_14 | transposase zinc-binding domain-containing protein | - |
| HTC40_RS00080 (D616_p108020) | 14245..14949 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HTC40_RS00085 (D616_p108021) | 14999..15718 | + | 720 | Protein_16 | helicase RepA family protein | - |
| HTC40_RS00090 (D616_p108022) | 15705..16556 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| HTC40_RS00095 (D616_p108023) | 16864..17679 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| HTC40_RS00100 (D616_p108024) | 17784..18542 | + | 759 | WP_001145207.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HTC40_RS00105 (D616_p108025) | 18542..19378 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| HTC40_RS00110 (D616_p108026) | 19439..20143 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HTC40_RS00115 (D616_p108027) | 20294..21109 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HTC40_RS00120 (D616_p108028) | 21299..22003 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HTC40_RS00125 (D616_p108029) | 22068..23318 | - | 1251 | Protein_24 | transposase | - |
| HTC40_RS00130 (D616_p108030) | 23393..24061 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| HTC40_RS00135 (D616_p108031) | 24097..24333 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| HTC40_RS00140 (D616_p108032) | 24330..24692 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| HTC40_RS00145 (D616_p108033) | 24710..26404 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| HTC40_RS00150 (D616_p108034) | 26456..26878 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| HTC40_RS00155 (D616_p108035) | 26914..27189 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| HTC40_RS00160 (D616_p108036) | 27203..27553 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| HTC40_RS00165 (D616_p108037) | 27625..28059 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| HTC40_RS00170 (D616_p108040) | 28902..29144 | + | 243 | WP_000844627.1 | transposase | - |
| HTC40_RS00175 (D616_p108041) | 29176..29826 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HTC40_RS00180 (D616_p108042) | 29932..31131 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| HTC40_RS00185 (D616_p108043) | 31163..32047 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| HTC40_RS00190 (D616_p108044) | 32185..32577 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| HTC40_RS00195 (D616_p108045) | 32581..34332 | + | 1752 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HTC40_RS00205 (D616_p108047) | 34339..36072 | + | 1734 | WP_225379986.1 | colicin Ia central receptor-binding domain-containing protein | - |
| HTC40_RS00210 (D616_p108048) | 36090..36437 | - | 348 | WP_000762572.1 | colicin E1 family microcin immunity protein | - |
| HTC40_RS00215 | 36556..36903 | + | 348 | WP_000142445.1 | DUF6404 family protein | - |
| HTC40_RS00220 (D616_p108049) | 36923..37108 | - | 186 | Protein_42 | hypothetical protein | - |
| HTC40_RS00225 | 37523..37825 | - | 303 | WP_001245884.1 | hypothetical protein | - |
| HTC40_RS00230 (D616_p108050) | 37822..38448 | - | 627 | WP_000587689.1 | ParA family plasmid-partitioning AAA ATPase | - |
| HTC40_RS00235 (D616_p108051) | 38652..39923 | - | 1272 | WP_000457473.1 | Y-family DNA polymerase | - |
| HTC40_RS00240 (D616_p108052) | 39923..40360 | - | 438 | WP_000109077.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HTC40_RS00245 (D616_p108053) | 40357..40605 | - | 249 | WP_000619113.1 | DinI-like family protein | - |
| HTC40_RS00250 (D616_p108054) | 41628..43352 | + | 1725 | WP_000138832.1 | group II intron reverse transcriptase/maturase | - |
| HTC40_RS00255 (D616_p108055) | 43429..44331 | + | 903 | WP_023842311.1 | DUF1281 domain-containing protein | - |
| HTC40_RS00260 | 44328..44639 | + | 312 | WP_012680995.1 | hypothetical protein | - |
| HTC40_RS00265 (D616_p108057) | 44716..45399 | + | 684 | WP_000086152.1 | DNA methylase | - |
| HTC40_RS00270 (D616_p108058) | 45400..45621 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| HTC40_RS00275 (D616_p108059) | 45635..46069 | + | 435 | WP_000274500.1 | DUF1380 family protein | - |
| HTC40_RS00280 (D616_p108060) | 46115..46891 | + | 777 | WP_001005043.1 | hypothetical protein | - |
| HTC40_RS00285 (D616_p108062) | 47309..47734 | + | 426 | WP_001198938.1 | antirestriction protein | - |
| HTC40_RS00290 (D616_p108063) | 47781..48200 | + | 420 | WP_000271736.1 | DUF1380 family protein | - |
| HTC40_RS00295 | 48200..48391 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| HTC40_RS00300 (D616_p108065) | 49160..49687 | + | 528 | WP_001276120.1 | single-stranded DNA-binding protein | - |
| HTC40_RS00305 (D616_p108066) | 49745..49978 | + | 234 | WP_000006024.1 | DUF905 domain-containing protein | - |
| HTC40_RS00310 (D616_p108068) | 50037..51995 | + | 1959 | WP_001145479.1 | ParB/RepB/Spo0J family partition protein | - |
| HTC40_RS00315 (D616_p108067) | 52050..52484 | + | 435 | WP_000845897.1 | conjugation system SOS inhibitor PsiB | - |
| HTC40_RS00320 (D616_p108069) | 52481..53200 | + | 720 | WP_001276263.1 | plasmid SOS inhibition protein A | - |
| HTC40_RS00325 (D616_p108070) | 53197..53793 | + | 597 | WP_000978012.1 | hypothetical protein | - |
| HTC40_RS00330 (D616_p108072) | 54256..54756 | + | 501 | WP_000117622.1 | antirestriction protein ArdA | - |
| HTC40_RS00335 (D616_p108075) | 55487..55921 | + | 435 | WP_000218850.1 | hypothetical protein | - |
| HTC40_RS00340 (D616_p108076) | 56014..56280 | + | 267 | WP_001247861.1 | hypothetical protein | - |
| HTC40_RS00345 (D616_p108077) | 56471..56860 | + | 390 | WP_001317525.1 | hypothetical protein | - |
| HTC40_RS00350 (D616_p108078) | 56857..57783 | + | 927 | WP_000038345.1 | ISNCY family transposase ISRor2 | VF |
| HTC40_RS00355 (D616_p108079) | 57783..58004 | + | 222 | WP_009453089.1 | hypothetical protein | - |
| HTC40_RS00360 (D616_p108080) | 58035..58286 | - | 252 | WP_000148285.1 | helix-turn-helix transcriptional regulator | - |
| HTC40_RS00365 (D616_p108083) | 58865..59713 | + | 849 | WP_001077046.1 | DUF4942 domain-containing protein | - |
| HTC40_RS00370 (D616_p108084) | 59798..60133 | - | 336 | WP_000157096.1 | hypothetical protein | - |
| HTC40_RS00375 (D616_p108085) | 60366..60698 | + | 333 | WP_001291058.1 | plasmid mobilization protein MobA | - |
| HTC40_RS00380 (D616_p108086) | 60710..63421 | + | 2712 | WP_000991386.1 | hypothetical protein | Relaxase |
| HTC40_RS00385 (D616_p108087) | 63489..63920 | + | 432 | WP_001335086.1 | cell envelope integrity TolA C-terminal domain-containing protein | - |
| HTC40_RS00390 (D616_p108088) | 64018..64248 | - | 231 | WP_071985462.1 | hypothetical protein | - |
| HTC40_RS00395 (D616_p108090) | 64715..67018 | - | 2304 | WP_000077652.1 | F-type conjugative transfer protein TrbC | - |
| HTC40_RS00400 (D616_p108091) | 66999..68117 | - | 1119 | WP_000155611.1 | DsbC family protein | - |
| HTC40_RS00405 (D616_p108092) | 68114..69403 | - | 1290 | WP_000121923.1 | IncI1-type conjugal transfer protein TrbA | - |
| HTC40_RS00725 | 69901..69996 | + | 96 | WP_000609151.1 | DinQ-like type I toxin DqlB | - |
| HTC40_RS00415 (D616_p108094) | 70139..70411 | - | 273 | WP_235674055.1 | flagellar biosynthesis protein FlgM | - |
| HTC40_RS00420 (D616_p108095) | 70478..70669 | - | 192 | WP_000264906.1 | hypothetical protein | - |
| HTC40_RS00425 | 70682..71044 | - | 363 | WP_000997721.1 | hypothetical protein | - |
| HTC40_RS00430 | 71178..71387 | + | 210 | WP_050561356.1 | hypothetical protein | - |
| HTC40_RS00435 (D616_p108097) | 71550..75641 | - | 4092 | WP_075051281.1 | Serine protease SepA autotransporter | VF |
| HTC40_RS00440 (D616_p108098) | 76043..76510 | - | 468 | WP_000598959.1 | thermonuclease family protein | - |
| HTC40_RS00445 (D616_p108099) | 76669..77292 | + | 624 | WP_001158020.1 | hypothetical protein | - |
| HTC40_RS00450 (D616_p108100) | 77380..77835 | + | 456 | WP_001205146.1 | DUF2569 family protein | - |
| HTC40_RS00455 (D616_p108101) | 78035..79570 | + | 1536 | WP_001317519.1 | phosphoethanolamine transferase | - |
| HTC40_RS00460 (D616_p108102) | 79663..80025 | - | 363 | WP_000551913.1 | hypothetical protein | - |
| HTC40_RS00465 (D616_p108103) | 80237..80389 | + | 153 | WP_001444391.1 | Hok/Gef family protein | - |
| HTC40_RS00705 | 80461..80547 | - | 87 | Protein_92 | antitoxin | - |
| HTC40_RS00710 | 80704..80835 | - | 132 | Protein_93 | ethanolamine utilization protein EutE | - |
| HTC40_RS00475 (D616_p108106) | 80937..81146 | + | 210 | WP_000062945.1 | HEAT repeat domain-containing protein | - |
| HTC40_RS00480 (D616_p108107) | 81211..81855 | - | 645 | WP_001005412.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| HTC40_RS00485 (D616_p108108) | 81942..84107 | - | 2166 | WP_000691803.1 | DotA/TraY family protein | - |
| HTC40_RS00490 | 84180..84749 | - | 570 | WP_181411561.1 | conjugal transfer protein TraX | - |
| HTC40_RS00495 (D616_p108109) | 84746..85951 | - | 1206 | WP_001189542.1 | conjugal transfer protein TraW | - |
| HTC40_RS00500 (D616_p108110) | 85909..86529 | - | 621 | WP_000286859.1 | hypothetical protein | - |
| HTC40_RS00505 (D616_p108111) | 86529..89573 | - | 3045 | WP_001024762.1 | hypothetical protein | - |
| HTC40_RS00510 | 89798..90343 | + | 546 | WP_001369268.1 | hypothetical protein | - |
| HTC40_RS00515 (D616_p108113) | 90316..90699 | - | 384 | WP_001369266.1 | hypothetical protein | - |
| HTC40_RS00520 (D616_p108114) | 90696..91055 | - | 360 | WP_000379509.1 | hypothetical protein | - |
| HTC40_RS00525 (D616_p108115) | 91114..91932 | - | 819 | WP_072112391.1 | conjugal transfer protein TraT | - |
| HTC40_RS00730 | 91847..92098 | - | 252 | WP_001277575.1 | hypothetical protein | - |
| HTC40_RS00535 (D616_p108117) | 92155..92553 | - | 399 | WP_000086067.1 | hypothetical protein | - |
| HTC40_RS00540 (D616_p108118) | 92602..93132 | - | 531 | WP_000987022.1 | conjugal transfer protein TraQ | - |
| HTC40_RS00545 (D616_p108119) | 93129..93842 | - | 714 | WP_000787008.1 | conjugal transfer protein TraP | - |
| HTC40_RS00550 (D616_p108120) | 93839..95170 | - | 1332 | WP_001272016.1 | conjugal transfer protein TraO | - |
| HTC40_RS00555 (D616_p108121) | 95174..96148 | - | 975 | WP_001165564.1 | hypothetical protein | VF |
| HTC40_RS00560 (D616_p108122) | 96159..96854 | - | 696 | WP_001287263.1 | DotI/IcmL family type IV secretion protein | - |
| HTC40_RS00565 (D616_p108123) | 96866..97216 | - | 351 | WP_001056369.1 | hypothetical protein | - |
| HTC40_RS00570 (D616_p108124) | 97233..101249 | - | 4017 | WP_000842446.1 | LPD7 domain-containing protein | - |
| HTC40_RS00720 | 101313..101603 | - | 291 | WP_000817799.1 | hypothetical protein | - |
| HTC40_RS00580 (D616_p108126) | 101600..102748 | - | 1149 | WP_000625246.1 | putative protein YggR | VF |
| HTC40_RS00585 (D616_p108127) | 102732..103568 | - | 837 | WP_000848138.1 | hypothetical protein | VF |
| HTC40_RS00590 (D616_p108128) | 103565..103882 | - | 318 | WP_023842850.1 | hypothetical protein | - |
| HTC40_RS00595 (D616_p108129) | 104241..105443 | - | 1203 | WP_000980149.1 | conjugal transfer protein TraF | - |
| HTC40_RS00600 (D616_p108130) | 105532..106353 | - | 822 | WP_000804092.1 | hypothetical protein | - |
| HTC40_RS00605 (D616_p108131) | 106623..106943 | + | 321 | WP_000695055.1 | hypothetical protein | - |
| HTC40_RS00610 | 107034..107201 | - | 168 | WP_001379384.1 | hypothetical protein | - |
| HTC40_RS00615 (D616_p108133) | 107366..108535 | - | 1170 | WP_000486830.1 | site-specific integrase | - |
| HTC40_RS00620 (D616_p108134) | 109149..110513 | - | 1365 | WP_001168069.1 | hypothetical protein | VF |
| HTC40_RS00625 (D616_p108135) | 110518..111153 | - | 636 | WP_000478594.1 | prepilin peptidase | - |
| HTC40_RS00630 (D616_p108136) | 111172..111645 | - | 474 | WP_000870986.1 | hypothetical protein | VF |
| HTC40_RS00635 (D616_p108137) | 111699..112235 | - | 537 | WP_001011158.1 | type 4 pilus major pilin | - |
| HTC40_RS00640 (D616_p108138) | 112309..113409 | - | 1101 | WP_000670138.1 | hypothetical protein | VF |
| HTC40_RS00645 (D616_p108139) | 113411..114919 | - | 1509 | WP_000886636.1 | hypothetical protein | VF |
| HTC40_RS00650 (D616_p108140) | 115004..115456 | - | 453 | WP_001112925.1 | type IV pilus biogenesis protein PilP | - |
| HTC40_RS00655 (D616_p108141) | 115446..116741 | - | 1296 | WP_000129891.1 | type 4b pilus protein PilO2 | - |
| HTC40_RS00660 (D616_p108142) | 116762..118381 | - | 1620 | WP_001034998.1 | Outer membrane lipoprotein BfpB | VF |
| HTC40_RS00665 (D616_p108143) | 118412..118849 | - | 438 | WP_000539685.1 | type IV pilus biogenesis protein PilM | - |
| HTC40_RS00670 (D616_p108144) | 118854..119921 | - | 1068 | WP_001170195.1 | hypothetical protein | VF |
| HTC40_RS00675 (D616_p108145) | 120078..120413 | - | 336 | WP_024186155.1 | hypothetical protein | - |
| HTC40_RS00680 (D616_p108146) | 120530..120772 | - | 243 | WP_001271734.1 | PilI type IV pilus biogenesis protein | - |
| HTC40_RS00685 (D616_p108147) | 120853..122547 | - | 1695 | WP_000482663.1 | flotillin family protein | - |
| HTC40_RS00690 (D616_p108148) | 122574..123194 | - | 621 | WP_000176497.1 | DUF1449 family protein | - |
| HTC40_RS00695 (D616_p108149) | 123461..124126 | - | 666 | WP_000154143.1 | hypothetical protein | - |
| HTC40_RS00700 (D616_p108150) | 124267..124908 | - | 642 | WP_000335846.1 | transcription termination/antitermination NusG family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|---|---|---|---|---|---|
| Escherichia coli | Conjugative plasmid | TA6132 | NC_022992 | 1..115452 | 0.002 | |
| Escherichia coli | Conjugative plasmid | TA6132 | NC_022992 | 1..115452 | 0.002 | |
| Escherichia coli strain 20Ec-P-124 | Conjugative plasmid | TA31223 | NZ_AP017613 | 1..108957 | 0.01 | |
| Escherichia coli strain E2863 | Conjugative plasmid | TA32350 | NZ_AP018803 | 1..124261 | 0.007 | |
| Escherichia coli O111:H- strain 110512 | Conjugative plasmid | TA33035 | NZ_AP019762 | 1..118827 | 0.007 | |
| Escherichia coli strain 2009C-3133 | Conjugative plasmid | TA57718 | NZ_CP013024 | 1..120611 | 0.006 | |
| Escherichia coli strain 97-3250 | Conjugative plasmid | TA99741 | NZ_CP027600 | 1..120604 | 0.006 |