SecReT4
T4SS ID506
StrainOrientia tsutsugamushi str. Boryong
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_009488
Location2998..8389; 279441..281657; 332462..333914; 924051..926504; 1876748..1891693
NameVirB
FunctionNA
ClassificationType IVA; Type P
sequence This T4SS has been mentioned in a genome sequencing report.

T4SS components
ComponentVirB1VirB2VirB3VirB4VirB5VirB6VirB7VirB8VirB9
Number001205022
ComponentVirB10VirB11VirD4
Number111

The information of T4SS components from NC_009488
Region 1: 2998..8389
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1OTBS_0001 (dnaA)22..1431 [+], 1410148283998chromosome replication initiator DnaA 
2OTBS_0002 (dnaN)1450..2748 [+], 1299148283999DNA polymerase III subunit beta 
3OTBS_0003 (virB8)2998..3678 [+], 681148284000type IV secretion system protein  VirB8
4OTBS_0004 (virB9)3698..4099 [+], 402148284001type IV secretion system protein  VirB9
5OTBS_0005 (virB10)4099..5628 [+], 1530148284002type IV secretion system protein  VirB10
6OTBS_0006 (virB11)5628..6617 [+], 990148284003type IV secretion system ATPase VirB11  VirB11
7OTBS_0007 (virD4)6617..8389 [+], 1773148284004type IV secretion system component VirD4  VirD4
8OTBS_0009 (rhp2)10369..12168 [+], 1800148284005hypothetical protein 
 
Region 2: 279441..281657
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1OTBS_0282275561..276760 [-], 1200148284153hypothetical protein 
2OTBS_0283 (coxB)277193..277945 [-], 753148284154cytochrome c oxidase polypeptide II 
3OTBS_0284278100..278576 [-], 477148284155hypothetical protein 
4OTBS_0285 (TrbL/VirB6)279441..281657 [+], 2217148284156conjugal transfer protein  VirB6
5OTBS_0289283403..283642 [-], 240148284157hypothetical protein 
6OTBS_0290 (tpr1B4)283817..284191 [-], 375148284158hypothetical protein 
 
Region 3: 332462..333914
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1OTBS_0332 (corC)327898..328812 [-], 915148284176Mg2+/Co2+ transporter 
2OTBS_0333328825..329328 [-], 504148284177metalloprotease 
3OTBS_0336 (ftsY)330765..331703 [-], 939148284178cell division ABC transporter, periplasmic substrate-binding protein 
4OTBS_0337331813..332202 [+], 390148284179hypothetical protein 
5OTBS_0338 (trbG/virB9)332462..333223 [-], 762148284180conjugal transfer protein  VirB9
6OTBS_0339 (virB8)333213..333914 [-], 702148284181type IV secretion system protein  VirB8
7OTBS_0340 (thyX)337492..338394 [-], 903148284182FAD-dependent thymidylate synthase 
 
Region 4: 924051..926504
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1OTBS_0949 (proS)919835..921136 [-], 1302148284536prolyl-tRNA synthetase 
2OTBS_0950921150..921443 [-], 294148284537hypothetical protein 
3OTBS_0951921467..922678 [-], 1212148284538phosphoglycerate kinase 
4OTBS_0952 (gap)922760..923776 [-], 1017148284539glyceraldehyde-3-phosphate dehydrogenase 
5OTBS_0953 (virB4-2)924051..926504 [+], 2454148284540virB4 protein precursor  VirB4
6OTBS_0954926504..931030 [+], 4527148284541hypothetical protein 
 
Region 5: 1876748..1891693
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1OTBS_19461871912..1872700 [-], 789148285046hypothetical protein 
2OTBS_1947 (metG)1872713..1874248 [-], 1536148285047methionyl-tRNA synthetase 
3OTBS_1948 (priA)1874433..1876373 [+], 1941148285048primosome assembly protein PriA 
4OTBS_1949 (virB3)1876748..1877035 [+], 288148285049type IV secretion system protein VirB3  VirB3
5OTBS_1950 (virB4)1877046..1879463 [+], 2418148285050type IV secretion system ATPase VirB4  VirB4
6OTBS_1951 (virB6-1)1879463..1881910 [+], 2448148285051type IV secretion system protein  VirB6
7OTBS_1952 (virB6-2)1881932..1885804 [+], 3873148285052type IV secretion system protein  VirB6
8OTBS_1953 (virB6-3)1885858..1889133 [+], 3276148285053type IV secretion system protein  VirB6
9OTBS_1954 (virB6-4)1889126..1891693 [+], 2568148285054type IV secretion system protein  VirB6
10OTBS_1955 (proP)1891730..1892983 [+], 1254148285055proline/betaine transporter 
11OTBS_1956 (mutL)1893012..1895054 [+], 2043148285056DNA mismatch repair protein 
12OTBS_1957 (gltX)1895180..1896580 [+], 1401148285057glutamyl-tRNA synthetase 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes
(1) Sonthayanon P; Peacock SJ; Chierakul W; Wuthiekanun V; Blacksell SD; Holden MT; Bentley SD; Feil EJ; Day NP (2010). High rates of homologous recombination in the mite endosymbiont and opportunistic human pathogen Orientia tsutsugamushi. PLoS Negl Trop Dis. 4(7):e752. [PudMed:20651929] experimental
(2) Cho NH; Kim HR; Lee JH; Kim SY; Kim J; Cha S; Kim SY; Darby AC; Fuxelius HH; Yin J; Kim JH; Kim J; Lee SJ; Koh YS; Jang WJ; Park KH; Andersson SG; Choi MS; Kim IS (2007). The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes. Proc Natl Acad Sci U S A. 104(19):7981-6. [PudMed:17483455]
 
experimental This literature contains experimental investigation

Genomics & Bioinformatics Group in MML, SJTU