Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EL079_RS03625 Genome accession   NZ_LR134283
Coordinates   727918..729906 (-) Length   662 a.a.
NCBI ID   WP_003030651.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC10713     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 722918..734906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL079_RS03600 (NCTC10713_00762) hemW 723591..724721 (-) 1131 WP_003030655.1 radical SAM family heme chaperone HemW -
  EL079_RS03605 (NCTC10713_00763) - 724846..726486 (-) 1641 WP_003030632.1 hypothetical protein -
  EL079_RS03610 (NCTC10713_00764) pptA 726476..727219 (-) 744 WP_003030627.1 ABC transporter ATP-binding protein Regulator
  EL079_RS09790 - 727347..727887 (-) 541 Protein_706 DUF1697 domain-containing protein -
  EL079_RS03625 (NCTC10713_00766) uvrB 727918..729906 (-) 1989 WP_003030651.1 excinuclease ABC subunit UvrB Machinery gene
  EL079_RS03630 (NCTC10713_00767) - 729997..730956 (-) 960 WP_003030658.1 CPBP family intramembrane glutamic endopeptidase -
  EL079_RS03635 (NCTC10713_00768) - 731119..733302 (+) 2184 WP_003032255.1 ABC transporter substrate-binding protein/permease -
  EL079_RS03640 (NCTC10713_00769) - 733302..734042 (+) 741 WP_003032251.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75663.54 Da        Isoelectric Point: 4.4831

>NTDB_id=999892 EL079_RS03625 WP_003030651.1 727918..729906(-) (uvrB) [Streptococcus anginosus strain NCTC10713]
MINRITDNKFKLVSKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGLEISRDQLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFMTNDENMEIAIGKIQAELEDQLGFFEREGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMVDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEREQTDTVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARAEKNERTFITTLTKKMAEDLTDYFKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
ITDSMQKAMDETARRRQIQMAYNEEHGIVPQTIQKEIRDLISVTKATLPDKEEVVDIESLNKQERKDMIKKLEGQMQEAA
GLLDFELAAQIRDMILEIKAVD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=999892 EL079_RS03625 WP_003030651.1 727918..729906(-) (uvrB) [Streptococcus anginosus strain NCTC10713]
ATGATAAATAGAATTACGGACAATAAATTTAAATTAGTTTCCAAGTATGAGCCTTCAGGAGATCAACCACAGGCGATTGA
GCAATTAGTGGATAATATAGAGGGTGGTGAGAAAGCTCAGATTCTCATGGGAGCGACAGGAACTGGAAAGACCTATACTA
TGAGTCAGGTCATCCAAAAGGTCAATAAACCGACCCTAGTTATCGCTCATAATAAAACTCTGGCTGGTCAGCTCTATGGT
GAATTTAAGGAGTTTTTTCCTGACAATGCGGTTGAATACTTCGTGTCTTACTATGACTATTACCAACCGGAAGCCTATGT
GCCTTCTAGTGATACCTATATTGAGAAGGACAGCTCGGTCAATGATGAGATTGACAAACTTCGTCACTCAGCAACCTCGG
CTCTCTTGGAGCGCAACGATGTGATTGTTGTGGCATCAGTCAGCTGCATTTATGGTTTGGGCTCGCCTAAGGAATACTCC
GATAGCGTGGTCAGTCTGCGACCTGGTTTAGAGATTTCACGGGATCAACTTCTCAATGATTTGGTTGATATTCAATTTGA
GCGCAATGATATTGACTTTCAACGAGGAAAATTTCGTGTGCGTGGCGATGTTGTGGAAATCTTCCCAGCTTCTCGCGATG
AACATGCCTTTCGGGTGGAATTTTTCGGGGATGAAATTGACCGCATTCGAGAAGTGGAAGCATTGACAGGTCAAGTGTTG
GGCGAAGTAGACCATTTAGCTATTTTCCCTGCCACTCACTTTATGACCAATGACGAAAATATGGAAATTGCCATTGGTAA
AATTCAAGCGGAATTAGAAGATCAGCTAGGCTTTTTTGAAAGAGAAGGGAAGCTTTTAGAAGCTCAGCGGTTGAAGCAAA
GAACGGACTATGATATTGAAATGCTGCGCGAAATGGGCTACACGAATGGTGTAGAGAATTATTCTCGCCACATGGACGGA
CGGAGTGAAGGTGAGCCACCTTACACTTTATTAGATTTCTTTCCTGATGATTTTTTAATCATGGTAGACGAAAGTCACAT
GACTATGGGGCAAATCAAAGGTATGTATAATGGTGACCGTTCTCGGAAAGAAATGTTGGTTAATTATGGATTTCGCTTAC
CTTCTGCCTTGGATAACCGTCCGTTGCGTCGGGAAGAATTTGAAAGTCATGTGCACCAGATTGTTTACGTGTCTGCTACA
CCAGGGGATTATGAGCGAGAGCAGACGGATACAGTAATTGAGCAAATTATTCGACCAACTGGACTGCTGGATCCAGAAGT
TGAAGTGCGTCCGACTATGGGGCAAATAGACGATCTTTTAGGGGAAATCAATGCGCGTGCAGAGAAGAATGAGCGAACCT
TTATCACAACGTTGACTAAAAAGATGGCAGAAGATCTGACGGATTACTTTAAAGAAATGGGTGTTAAGGTCAAATACATG
CACTCAGATATCAAGACTTTAGAGCGGACAGAAATTATCCGCGACCTGCGGTTAGGTGTCTTTGATGTTTTAGTCGGAAT
TAACCTGTTGCGTGAGGGAATTGATGTGCCAGAGGTTAGTCTGGTTGCCATTCTTGATGCAGACAAGGAAGGTTTCTTAC
GTAATGAGCGTGGTTTGATCCAAACCATTGGTCGGGCTGCCCGTAATAGTGAAGGCCACGTCATCATGTATGCGGACACG
ATTACAGATTCCATGCAAAAAGCTATGGATGAAACTGCCCGTCGTCGTCAGATTCAAATGGCTTATAACGAAGAACATGG
TATTGTACCGCAAACAATCCAGAAAGAAATCCGTGACCTAATCAGTGTGACAAAAGCCACTCTACCAGACAAGGAAGAAG
TGGTAGATATTGAAAGTCTTAATAAGCAGGAACGCAAGGATATGATTAAAAAGCTAGAAGGACAAATGCAAGAAGCTGCT
GGTCTTCTGGACTTCGAGCTGGCCGCCCAAATCCGCGATATGATTTTGGAGATTAAGGCGGTGGATTAG

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB/uvrC motif (UVR)

(626-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

92.598

100

0.926
  uvrB Streptococcus pneumoniae D39

92.598

100

0.926
  uvrB Streptococcus pneumoniae TIGR4

92.447

100

0.924

Multiple sequence alignment