Detailed information NTG0999536

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ABFJ86_RS04955
• Genome accession: NZ_CP155817
• Coordinates: 1008065..1009051 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CUBIST-1
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1003065..1014051

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABFJ86_RS04930 (ABFJ86_04950)	opp4B	1003279..1004241 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ABFJ86_RS04935 (ABFJ86_04955)	opp4C	1004253..1005134 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ABFJ86_RS04940 (ABFJ86_04960)	trpS	1005176..1006165 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ABFJ86_RS04945 (ABFJ86_04965)	spxA	1006459..1006854 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ABFJ86_RS04950 (ABFJ86_04970)	mecA	1007225..1007944 (+)	720	WP_001217728.1	adaptor protein MecA	-
ABFJ86_RS04955 (ABFJ86_04975)	coiA	1008065..1009051 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ABFJ86_RS04960 (ABFJ86_04980)	pepF	1009099..1010907 (+)	1809	WP_001655747.1	oligoendopeptidase F	-
ABFJ86_RS04965 (ABFJ86_04985)	yjbH	1011367..1012173 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ABFJ86_RS04970 (ABFJ86_04990)	-	1012196..1012561 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ABFJ86_RS04975 (ABFJ86_04995)	-	1012665..1013258 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ABFJ86_RS04980 (ABFJ86_05000)	-	1013444..1013791 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=999536 ABFJ86_RS04955 WP_000959282.1 1008065..1009051(+) (coiA) [Staphylococcus aureus strain CUBIST-1]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=999536 ABFJ86_RS04955 WP_000959282.1 1008065..1009051(+) (coiA) [Staphylococcus aureus strain CUBIST-1]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976