Detailed information NTG0999435

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: EL071_RS11700
• Genome accession: NZ_LR134265
• Coordinates: 2235799..2236245 (-)
• Length: 148 a.a.
• NCBI ID: WP_115356966.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NCTC8184
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2230799..2241245

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL071_RS11665 (NCTC8184_02327)	-	2231353..2232018 (-)	666	WP_000008107.1	type II CAAX endopeptidase family protein	-
EL071_RS11670 (NCTC8184_02328)	-	2232087..2232542 (-)	456	WP_115356965.1	hypothetical protein	-
EL071_RS11675	-	2232583..2232720 (-)	138	WP_001869149.1	hypothetical protein	-
EL071_RS11680 (NCTC8184_02329)	-	2232779..2232985 (-)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
EL071_RS11685 (NCTC8184_02330)	-	2233136..2234329 (-)	1194	WP_000047534.1	acetate kinase	-
EL071_RS11690 (NCTC8184_02331)	comGH	2234361..2235335 (-)	975	WP_001008571.1	class I SAM-dependent methyltransferase	Machinery gene
EL071_RS11695 (NCTC8184_02332)	comGG	2235450..2235821 (-)	372	WP_000601103.1	competence type IV pilus minor pilin ComGG	Machinery gene
EL071_RS11700 (NCTC8184_02333)	comGF	2235799..2236245 (-)	447	WP_115356966.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL071_RS11705 (NCTC8184_02334)	comGE	2236199..2236498 (-)	300	WP_038406052.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL071_RS11710 (NCTC8184_02335)	comGD	2236470..2236883 (-)	414	WP_115356967.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL071_RS11715 (NCTC8184_02336)	comGC/cglC	2236858..2237187 (-)	330	WP_115356968.1	competence type IV pilus major pilin ComGC	Machinery gene
EL071_RS11720 (NCTC8184_02337)	comGB	2237184..2238227 (-)	1044	WP_223297804.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL071_RS11725 (NCTC8184_02338)	comGA	2238121..2239092 (-)	972	WP_115356969.1	competence type IV pilus ATPase ComGA	Machinery gene
EL071_RS11735 (NCTC8184_02339)	-	2239264..2239629 (-)	366	WP_115356970.1	DUF1033 family protein	-

Sequence

Protein

• Length: 148 a.a.
• Molecular weight: 17313.31 Da
• Isoelectric Point: 9.8810

>NTDB_id=999435 EL071_RS11700 WP_115356966.1 2235799..2236245(-) (comGF) [Streptococcus agalactiae strain NCTC8184]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 447 bp

>NTDB_id=999435 EL071_RS11700 WP_115356966.1 2235799..2236245(-) (comGF) [Streptococcus agalactiae strain NCTC8184]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTGCTAGTTTATCAAGGACTAACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTCGAAGGCGCTCACTTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTGTTTTTTATTTTAAGG
ACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-137)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	45.775	95.946	0.439
comGF	Streptococcus mutans UA140	45.775	95.946	0.439
comGF/cglF	Streptococcus pneumoniae D39	41.727	93.919	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	41.727	93.919	0.392
comGF/cglF	Streptococcus pneumoniae R6	41.727	93.919	0.392
comGF/cglF	Streptococcus pneumoniae Rx1	41.727	93.919	0.392
comGF/cglF	Streptococcus mitis SK321	42.537	90.541	0.385
comGF	Lactococcus lactis subsp. cremoris KW2	40	94.595	0.378
comGF/cglF	Streptococcus mitis NCTC 12261	41.791	90.541	0.378