Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL020_RS06140 Genome accession   NZ_LR134203
Coordinates   1190760..1192088 (-) Length   442 a.a.
NCBI ID   WP_020916819.1    Uniprot ID   A0AB33ALY3
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1185760..1197088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS06115 (NCTC11436_01277) deoC 1186093..1186758 (-) 666 WP_020916815.1 deoxyribose-phosphate aldolase -
  EL020_RS06120 (NCTC11436_01278) - 1187262..1187855 (-) 594 WP_020916816.1 class I SAM-dependent methyltransferase -
  EL020_RS06125 (NCTC11436_01279) coaA 1187987..1188907 (+) 921 WP_020916817.1 type I pantothenate kinase -
  EL020_RS06130 (NCTC11436_01280) rpsT 1188983..1189234 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  EL020_RS06135 - 1189366..1190717 (+) 1352 WP_126402565.1 IS3 family transposase -
  EL020_RS06140 (NCTC11436_01283) ciaH 1190760..1192088 (-) 1329 WP_020916819.1 sensor histidine kinase Regulator
  EL020_RS06145 (NCTC11436_01284) ciaR 1192078..1192752 (-) 675 WP_020916820.1 response regulator transcription factor Regulator
  EL020_RS06150 (NCTC11436_01285) - 1192920..1195463 (-) 2544 WP_126402566.1 M1 family metallopeptidase -
  EL020_RS06155 (NCTC11436_01286) phoU 1195694..1196347 (-) 654 WP_020916822.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 50230.16 Da        Isoelectric Point: 6.5190

>NTDB_id=998249 EL020_RS06140 WP_020916819.1 1190760..1192088(-) (ciaH) [Streptococcus lutetiensis strain NCTC11436]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSIQSNNSFSN
SGKSKPSSNVASLSNVSVLLYDTNGKIVNAIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVSHNF
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRYNFGK

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=998249 EL020_RS06140 WP_020916819.1 1190760..1192088(-) (ciaH) [Streptococcus lutetiensis strain NCTC11436]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACTACTTTAAAAAATG
CAGCTGACAATGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCATACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAAGTAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTACTGTACGATACAAATGGGAAAAT
CGTAAATGCAATTGATGCGTTTGTCCAGTTCGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ATGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACAGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCTTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGACCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAATCTTGCTAGGCGAGATGATGGATTGAAAGTTGAATTAGAAGAAATTCAAC
CTTCAATATTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAACGGTAAAACTTTTGTTTCTCATAATTTT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGATGACGGTTTTATTGAATTTACGGTTAAAACAACAGAACGCCAGACTATTCTAACCGTTGCTGATAATGGACCGG
GTATTAGTGACGCCGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGGCTTGGGCTATCTTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGACATTCAAGTTAAGGATAATCATCCAAA
AGGAACCATATTTGAAGTTCGTTTTAACCGATATAATTTTGGTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33ALY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.77

98.416

0.588
  ciaH Streptococcus pneumoniae Rx1

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae D39

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae R6

52.403

98.869

0.518
  ciaH Streptococcus pneumoniae TIGR4

52.403

98.869

0.518

Multiple sequence alignment