Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   ABC806_RS01090 Genome accession   NZ_CP155539
Coordinates   212526..212939 (+) Length   137 a.a.
NCBI ID   WP_000265622.1    Uniprot ID   Q8CY84
Organism   Streptococcus pneumoniae TIGR4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 207526..217939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC806_RS01050 (ABC806_01050) - 207579..208637 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  ABC806_RS01055 (ABC806_01055) - 208788..209153 (+) 366 WP_000286415.1 DUF1033 family protein -
  ABC806_RS01060 (ABC806_01060) comGA/cglA/cilD 209229..210170 (+) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  ABC806_RS01065 (ABC806_01065) comGB/cglB 210118..211134 (+) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABC806_RS01070 (ABC806_01070) comGC/cglC 211136..211462 (+) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  ABC806_RS01075 (ABC806_01075) comGD/cglD 211455..211859 (+) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABC806_RS01080 (ABC806_01080) comGE/cglE 211822..212124 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABC806_RS01085 (ABC806_01085) comGF/cglF 212087..212548 (+) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABC806_RS01090 (ABC806_01090) comGG/cglG 212526..212939 (+) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  ABC806_RS01095 (ABC806_01095) - 213076..213670 (+) 595 Protein_199 methyltransferase domain-containing protein -
  ABC806_RS01100 (ABC806_01100) comYH 213731..214684 (+) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  ABC806_RS01105 (ABC806_01105) - 214735..215925 (+) 1191 WP_000167757.1 acetate kinase -
  ABC806_RS01110 (ABC806_01110) - 215926..216057 (+) 132 WP_000768904.1 hypothetical protein -
  ABC806_RS01115 (ABC806_01115) rnpA 216074..216445 (+) 372 WP_000739253.1 ribonuclease P protein component -
  ABC806_RS01120 (ABC806_01120) - 216420..217244 (+) 825 WP_000727904.1 membrane protein insertase YidC -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 16003.46 Da        Isoelectric Point: 10.2472

>NTDB_id=997549 ABC806_RS01090 WP_000265622.1 212526..212939(+) (comGG/cglG) [Streptococcus pneumoniae TIGR4]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNKEKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKK
TGLVTRVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=997549 ABC806_RS01090 WP_000265622.1 212526..212939(+) (comGG/cglG) [Streptococcus pneumoniae TIGR4]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAATTGGTTGCTTTTGCTATGGCTA
AACGAACCAAAGATAAGGTTGAGCAAGAAAGTGGGGAACAGTTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTAGTGACGAGGGTTCGTACGGATAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCATAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q8CY84

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus pneumoniae Rx1

100

100

1

  comGG/cglG Streptococcus pneumoniae D39

100

100

1

  comGG/cglG Streptococcus pneumoniae R6

100

100

1

  comGG/cglG Streptococcus pneumoniae TIGR4

100

100

1

  comGG/cglG Streptococcus mitis SK321

87.591

100

0.876

  comGG/cglG Streptococcus mitis NCTC 12261

89.256

88.321

0.788

  comYG Streptococcus mutans UA140

38.806

97.81

0.38

  comYG Streptococcus mutans UA159

38.806

97.81

0.38


Multiple sequence alignment