Detailed information NTG0997476

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ABC812_RS04410
• Genome accession: NZ_CP155537
• Coordinates: 865554..866507 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain DP1322
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 860554..871507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC812_RS04385 (ABC812_04385)	rpmG	861297..861446 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
ABC812_RS04390 (ABC812_04390)	secG	861486..861719 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
ABC812_RS04395 (ABC812_04395)	rnr	861821..864175 (+)	2355	WP_000654897.1	ribonuclease R	-
ABC812_RS04400 (ABC812_04400)	smpB	864138..864605 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
ABC812_RS04405 (ABC812_04405)	tehB	864621..865481 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
ABC812_RS04410 (ABC812_04410)	coiA	865554..866507 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
ABC812_RS04415 (ABC812_04415)	pepF	866526..868328 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
ABC812_RS04420 (ABC812_04420)	-	868330..869043 (+)	714	WP_000230399.1	O-methyltransferase	-
ABC812_RS04425 (ABC812_04425)	prsA	869110..870051 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
ABC812_RS04430 (ABC812_04430)	-	870170..870511 (-)	342	Protein_873	IS3 family transposase	-
ABC812_RS04435 (ABC812_04435)	-	870923..871018 (+)	96	Protein_874	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=997476 ABC812_RS04410 WP_000495911.1 865554..866507(+) (coiA) [Streptococcus pneumoniae strain DP1322]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=997476 ABC812_RS04410 WP_000495911.1 865554..866507(+) (coiA) [Streptococcus pneumoniae strain DP1322]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435