Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ABC804_RS01170 Genome accession   NZ_CP155536
Coordinates   224071..224778 (-) Length   235 a.a.
NCBI ID   WP_000166477.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M264-3     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 219071..229778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC804_RS01145 (ABC804_01145) pstB 219154..219906 (-) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  ABC804_RS01150 (ABC804_01150) pstA 219908..220723 (-) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  ABC804_RS01155 (ABC804_01155) pstC 220716..221579 (-) 864 WP_000165889.1 phosphate ABC transporter permease subunit PstC -
  ABC804_RS01160 (ABC804_01160) - 221697..222572 (-) 876 WP_000669493.1 substrate-binding domain-containing protein -
  ABC804_RS01165 (ABC804_01165) pnpS 222739..224070 (-) 1332 WP_000833266.1 two-component system histidine kinase PnpS -
  ABC804_RS01170 (ABC804_01170) vicR 224071..224778 (-) 708 WP_000166477.1 response regulator transcription factor Regulator
  ABC804_RS01175 (ABC804_01175) - 224862..225347 (-) 486 WP_001821625.1 cupin domain-containing protein -
  ABC804_RS01180 (ABC804_01180) - 225333..225890 (+) 558 Protein_225 transposase -
  ABC804_RS01185 (ABC804_01185) argS 226280..227971 (-) 1692 WP_001092701.1 arginine--tRNA ligase -
  ABC804_RS01190 (ABC804_01190) argR 228119..228565 (+) 447 WP_001231472.1 arginine repressor -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27254.62 Da        Isoelectric Point: 6.6568

>NTDB_id=997394 ABC804_RS01170 WP_000166477.1 224071..224778(-) (vicR) [Streptococcus pneumoniae strain M264-3]
MTKQVLLVDDEEHILRLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=997394 ABC804_RS01170 WP_000166477.1 224071..224778(-) (vicR) [Streptococcus pneumoniae strain M264-3]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAGATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATAGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCATCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCACGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATTG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAGGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGATATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.202

99.149

0.409
  covR Streptococcus salivarius strain HSISS4

40.171

99.574

0.4

Multiple sequence alignment