Detailed information NTG0997164

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ABC814_RS04540
• Genome accession: NZ_CP155533
• Coordinates: 880529..882769 (+)
• Length: 746 a.a.
• NCBI ID: WP_083973668.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Spn1439-106
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 875529..887769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC814_RS04510 (ABC814_04510)	-	875680..876648 (+)	969	WP_000658183.1	PhoH family protein	-
ABC814_RS04515 (ABC814_04515)	-	876841..877341 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
ABC814_RS04520 (ABC814_04520)	-	877344..877670 (+)	327	Protein_891	TfoX/Sxy family protein	-
ABC814_RS04525 (ABC814_04525)	ald	877971..879081 (-)	1111	Protein_892	alanine dehydrogenase	-
ABC814_RS04530 (ABC814_04530)	-	879258..879827 (+)	570	WP_000443770.1	GNAT family N-acetyltransferase	-
ABC814_RS04535 (ABC814_04535)	comEA/celA/cilE	879895..880545 (+)	651	WP_000387347.1	helix-hairpin-helix domain-containing protein	Machinery gene
ABC814_RS04540 (ABC814_04540)	comEC/celB	880529..882769 (+)	2241	WP_083973668.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ABC814_RS04545 (ABC814_04545)	-	882911..883135 (+)	225	WP_015898758.1	hypothetical protein	-
ABC814_RS04550 (ABC814_04550)	-	883167..883754 (+)	588	WP_000933540.1	ABC transporter ATP-binding protein	-
ABC814_RS04555 (ABC814_04555)	-	883758..884942 (+)	1185	WP_000655947.1	ABC transporter permease	-
ABC814_RS04560 (ABC814_04560)	infC	885244..885774 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
ABC814_RS04565 (ABC814_04565)	rpmI	885807..886007 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
ABC814_RS04570 (ABC814_04570)	rplT	886059..886418 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
ABC814_RS04575 (ABC814_04575)	-	886476..886856 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84533.85 Da
• Isoelectric Point: 9.3992

>NTDB_id=997164 ABC814_RS04540 WP_083973668.1 880529..882769(+) (comEC/celB) [Streptococcus pneumoniae strain Spn1439-106]
MLQWIKNFSNPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLTQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASSPLVFGQPNEWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKTTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFVAELQATQTKVRSMTVGEYLPIFGSQLEVLSPREIGYGGHEDSLVLYGKL
LNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=997164 ABC814_RS04540 WP_083973668.1 880529..882769(+) (comEC/celB) [Streptococcus pneumoniae strain Spn1439-106]
ATGTTACAGTGGATTAAGAATTTCTCTAATCCCCTAATTTACCTGAGTTTTCTGTTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCTGCTA
GCAAAGTTCTAGTGATTTGTGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTACCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGACTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGGCAAGTAGTCCTCTAGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGACGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGTACTTGCCCATTTTCG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGGAAATTGGATATGGAGGTCATGAAGATTCCCTGGTTCTTTATGGGAAACTC
TTGAATAATCACTTTCTCTTCATAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGTACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGCTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-634)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	95.71	100	0.957
comEC/celB	Streptococcus pneumoniae Rx1	94.504	100	0.945
comEC/celB	Streptococcus pneumoniae D39	94.504	100	0.945
comEC/celB	Streptococcus pneumoniae R6	94.504	100	0.945
comEC/celB	Streptococcus mitis SK321	91.823	100	0.918
comEC/celB	Streptococcus mitis NCTC 12261	91.544	99.866	0.914
comEC	Lactococcus lactis subsp. cremoris KW2	44.399	99.33	0.441