Detailed information NTG0995985

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ABC964_RS13700
• Genome accession: NZ_CP155060
• Coordinates: 2725229..2726116 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CC5-MSSA
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2720229..2731116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC964_RS13670 (ABC964_13670)	-	2720248..2720340 (+)	93	WP_010956583.1	hypothetical protein	-
ABC964_RS13675 (ABC964_13675)	-	2720448..2720945 (-)	498	WP_001065268.1	glutathione peroxidase	-
ABC964_RS13680 (ABC964_13680)	-	2720955..2721215 (-)	261	WP_001791974.1	hypothetical protein	-
ABC964_RS13685 (ABC964_13685)	-	2721597..2721710 (-)	114	Protein_2654	hypothetical protein	-
ABC964_RS13690 (ABC964_13690)	-	2722369..2724369 (-)	2001	WP_000776751.1	ABC transporter permease	-
ABC964_RS13695 (ABC964_13695)	-	2724366..2725121 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ABC964_RS13700 (ABC964_13700)	braS	2725229..2726116 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ABC964_RS13705 (ABC964_13705)	braR	2726127..2726792 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ABC964_RS13710 (ABC964_13710)	-	2726818..2727018 (-)	201	WP_000604730.1	hypothetical protein	-
ABC964_RS13715 (ABC964_13715)	-	2727216..2728640 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ABC964_RS13720 (ABC964_13720)	-	2728710..2728820 (+)	111	Protein_2661	hypothetical protein	-
ABC964_RS13725 (ABC964_13725)	-	2728923..2729378 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ABC964_RS13730 (ABC964_13730)	-	2729623..2730384 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=995985 ABC964_RS13700 WP_000143425.1 2725229..2726116(-) (braS) [Staphylococcus aureus strain CC5-MSSA]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=995985 ABC964_RS13700 WP_000143425.1 2725229..2726116(-) (braS) [Staphylococcus aureus strain CC5-MSSA]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1