Detailed information NTG0994445

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AAYT23_RS04340
• Genome accession: NZ_CP154877
• Coordinates: 850370..851323 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 20234295
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 845370..856323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS04315 (AAYT23_04300)	rpmG	846113..846262 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
AAYT23_RS04320 (AAYT23_04305)	secG	846302..846535 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
AAYT23_RS04325 (AAYT23_04310)	rnr	846637..848991 (+)	2355	WP_000654917.1	ribonuclease R	-
AAYT23_RS04330 (AAYT23_04315)	smpB	848954..849421 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
AAYT23_RS04335 (AAYT23_04320)	tehB	849437..850297 (+)	861	WP_000413759.1	SAM-dependent methyltransferase TehB	-
AAYT23_RS04340 (AAYT23_04325)	coiA	850370..851323 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
AAYT23_RS04345 (AAYT23_04330)	pepF	851342..853144 (+)	1803	WP_000244136.1	oligoendopeptidase F	Regulator
AAYT23_RS04350 (AAYT23_04335)	-	853146..853859 (+)	714	WP_000230399.1	O-methyltransferase	-
AAYT23_RS04355 (AAYT23_04340)	prsA	853926..854867 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
AAYT23_RS04360 (AAYT23_04345)	-	854984..855325 (-)	342	Protein_859	transposase	-
AAYT23_RS04365 (AAYT23_04350)	-	855738..855833 (+)	96	Protein_860	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=994445 AAYT23_RS04340 WP_000495909.1 850370..851323(+) (coiA) [Streptococcus pneumoniae strain 20234295]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=994445 AAYT23_RS04340 WP_000495909.1 850370..851323(+) (coiA) [Streptococcus pneumoniae strain 20234295]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435