Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AAYT23_RS01685 Genome accession   NZ_CP154877
Coordinates   326451..327140 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20234295     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 321451..332140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT23_RS01660 (AAYT23_01655) gpsB 321560..321889 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AAYT23_RS01670 (AAYT23_01665) - 322375..323532 (+) 1158 WP_000711392.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  AAYT23_RS01675 (AAYT23_01670) mapZ 323545..324939 (+) 1395 WP_000039283.1 cell division site-positioning protein MapZ -
  AAYT23_RS01680 (AAYT23_01675) gndA 325015..326439 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  AAYT23_RS01685 (AAYT23_01680) covR 326451..327140 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  AAYT23_RS01690 (AAYT23_01685) cbpC 327238..328263 (+) 1026 WP_000698031.1 choline-binding protein CbpC -
  AAYT23_RS01695 (AAYT23_01690) - 328282..329157 (+) 876 WP_000771138.1 choline-binding protein CbpJ -
  AAYT23_RS01700 (AAYT23_01695) - 329275..330507 (-) 1233 WP_000765672.1 MFS transporter -
  AAYT23_RS01705 (AAYT23_01700) - 331037..331375 (-) 339 Protein_332 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=994430 AAYT23_RS01685 WP_000518011.1 326451..327140(+) (covR) [Streptococcus pneumoniae strain 20234295]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=994430 AAYT23_RS01685 WP_000518011.1 326451..327140(+) (covR) [Streptococcus pneumoniae strain 20234295]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment