Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EW023_RS05985 Genome accession   NZ_LR130239
Coordinates   1176960..1177922 (-) Length   320 a.a.
NCBI ID   WP_002983995.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain PS003 isolate PS003     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1171960..1182922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW023_RS05970 - 1172797..1173504 (-) 708 WP_002989211.1 O-methyltransferase -
  EW023_RS05975 - 1173570..1174766 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  EW023_RS05980 pepF 1175142..1176947 (-) 1806 WP_009880654.1 oligoendopeptidase F Regulator
  EW023_RS05985 coiA 1176960..1177922 (-) 963 WP_002983995.1 competence protein CoiA Machinery gene
  EW023_RS05990 - 1178148..1178864 (-) 717 WP_023612525.1 pseudouridine synthase -
  EW023_RS05995 nagB 1178983..1179687 (-) 705 WP_021340997.1 glucosamine-6-phosphate deaminase -
  EW023_RS06000 queA 1179889..1180917 (+) 1029 WP_023611686.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  EW023_RS06005 - 1180924..1182144 (+) 1221 WP_012560799.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37801.25 Da        Isoelectric Point: 10.2848

>NTDB_id=994429 EW023_RS05985 WP_002983995.1 1176960..1177922(-) (coiA) [Streptococcus pyogenes strain PS003 isolate PS003]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=994429 EW023_RS05985 WP_002983995.1 1176960..1177922(-) (coiA) [Streptococcus pyogenes strain PS003 isolate PS003]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGTAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTTTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTGCTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCATAATATTATGGAAATGTTTCGGTTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403