Detailed information NTG0994366

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AAYT22_RS04245
• Genome accession: NZ_CP154876
• Coordinates: 830433..832673 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942413.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20155336
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 825433..837673

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT22_RS04215 (AAYT22_04200)	-	825584..826552 (+)	969	WP_000658183.1	PhoH family protein	-
AAYT22_RS04220 (AAYT22_04205)	-	826745..827245 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
AAYT22_RS04225 (AAYT22_04210)	-	827248..827574 (+)	327	Protein_832	TfoX/Sxy family protein	-
AAYT22_RS04230 (AAYT22_04215)	ald	827875..828986 (-)	1112	Protein_833	alanine dehydrogenase	-
AAYT22_RS04235 (AAYT22_04220)	-	829163..829732 (+)	570	WP_000443743.1	GNAT family N-acetyltransferase	-
AAYT22_RS04240 (AAYT22_04225)	comEA/celA/cilE	829799..830449 (+)	651	WP_000387324.1	helix-hairpin-helix domain-containing protein	Machinery gene
AAYT22_RS04245 (AAYT22_04230)	comEC/celB	830433..832673 (+)	2241	WP_000942413.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAYT22_RS04250 (AAYT22_04235)	-	832852..833040 (+)	189	WP_001809102.1	hypothetical protein	-
AAYT22_RS04255 (AAYT22_04240)	-	833072..833659 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
AAYT22_RS04260 (AAYT22_04245)	-	833663..834844 (+)	1182	WP_000655952.1	membrane protein	-
AAYT22_RS04265 (AAYT22_04250)	infC	835151..835681 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
AAYT22_RS04270 (AAYT22_04255)	rpmI	835714..835914 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
AAYT22_RS04275 (AAYT22_04260)	rplT	835966..836325 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
AAYT22_RS04280 (AAYT22_04265)	-	836383..836763 (+)	381	WP_000157138.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84642.24 Da
• Isoelectric Point: 9.6735

>NTDB_id=994366 AAYT22_RS04245 WP_000942413.1 830433..832673(+) (comEC/celB) [Streptococcus pneumoniae strain 20155336]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSTSYLALLGFVFLLVCLFFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFFTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFIFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNTWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKNSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPYQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=994366 AAYT22_RS04245 WP_000942413.1 830433..832673(+) (comEC/celB) [Streptococcus pneumoniae strain 20155336]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTTTGGCTTTACTACGCCATTTT
TTCAACATCCTATCTTGCTTTGTTGGGATTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCTGCTA
GCAAAGTTCTAGTGATTTGTGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTTACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTATCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATACATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAAGCTTGATACCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAAACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCTATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	98.391	100	0.984
comEC/celB	Streptococcus pneumoniae D39	98.391	100	0.984
comEC/celB	Streptococcus pneumoniae R6	98.391	100	0.984
comEC/celB	Streptococcus pneumoniae TIGR4	97.587	100	0.976
comEC/celB	Streptococcus mitis SK321	91.287	100	0.913
comEC/celB	Streptococcus mitis NCTC 12261	90.872	99.866	0.908
comEC	Lactococcus lactis subsp. cremoris KW2	44.13	99.33	0.438