Detailed information NTG0994367

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AAYT22_RS04360
• Genome accession: NZ_CP154876
• Coordinates: 851368..852321 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 20155336
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 846368..857321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT22_RS04335 (AAYT22_04320)	rpmG	847111..847260 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
AAYT22_RS04340 (AAYT22_04325)	secG	847300..847533 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
AAYT22_RS04345 (AAYT22_04330)	rnr	847635..849989 (+)	2355	WP_000654917.1	ribonuclease R	-
AAYT22_RS04350 (AAYT22_04335)	smpB	849952..850419 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
AAYT22_RS04355 (AAYT22_04340)	tehB	850435..851295 (+)	861	WP_000413759.1	SAM-dependent methyltransferase TehB	-
AAYT22_RS04360 (AAYT22_04345)	coiA	851368..852321 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
AAYT22_RS04365 (AAYT22_04350)	pepF	852340..854142 (+)	1803	WP_000244136.1	oligoendopeptidase F	Regulator
AAYT22_RS04370 (AAYT22_04355)	-	854144..854857 (+)	714	WP_000230399.1	O-methyltransferase	-
AAYT22_RS04375 (AAYT22_04360)	prsA	854924..855865 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
AAYT22_RS04380 (AAYT22_04365)	-	855982..856323 (-)	342	Protein_863	transposase	-
AAYT22_RS04385 (AAYT22_04370)	-	856736..856831 (+)	96	Protein_864	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=994367 AAYT22_RS04360 WP_000495909.1 851368..852321(+) (coiA) [Streptococcus pneumoniae strain 20155336]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=994367 AAYT22_RS04360 WP_000495909.1 851368..852321(+) (coiA) [Streptococcus pneumoniae strain 20155336]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435