Detailed information NTG0994286

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: V6C35_RS13455
• Genome accession: NZ_CP154863
• Coordinates: 2689565..2690452 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN31-2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2684565..2695452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6C35_RS13425 (V6C35_013425)	-	2684583..2684675 (+)	93	WP_010956583.1	hypothetical protein	-
V6C35_RS13430 (V6C35_013430)	-	2684783..2685280 (-)	498	WP_001065268.1	glutathione peroxidase	-
V6C35_RS13435 (V6C35_013435)	-	2685290..2685550 (-)	261	WP_001791974.1	hypothetical protein	-
V6C35_RS13440 (V6C35_013440)	-	2685932..2686045 (-)	114	Protein_2608	hypothetical protein	-
V6C35_RS13445 (V6C35_013445)	-	2686705..2688705 (-)	2001	WP_000776751.1	ABC transporter permease	-
V6C35_RS13450 (V6C35_013450)	-	2688702..2689457 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
V6C35_RS13455 (V6C35_013455)	braS	2689565..2690452 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
V6C35_RS13460 (V6C35_013460)	braR	2690463..2691128 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
V6C35_RS13465 (V6C35_013465)	-	2691154..2691354 (-)	201	WP_000604730.1	hypothetical protein	-
V6C35_RS13470 (V6C35_013470)	-	2691552..2692976 (+)	1425	WP_000953755.1	alkaline phosphatase	-
V6C35_RS13475 (V6C35_013475)	-	2693046..2693156 (+)	111	Protein_2615	hypothetical protein	-
V6C35_RS13480 (V6C35_013480)	-	2693259..2693714 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
V6C35_RS13485 (V6C35_013485)	-	2693959..2694720 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=994286 V6C35_RS13455 WP_000143425.1 2689565..2690452(-) (braS) [Staphylococcus aureus strain BSN31-2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=994286 V6C35_RS13455 WP_000143425.1 2689565..2690452(-) (braS) [Staphylococcus aureus strain BSN31-2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1