Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EW024_RS05840 Genome accession   NZ_LR130237
Coordinates   1141603..1142565 (-) Length   320 a.a.
NCBI ID   WP_002983995.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1136603..1147565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS05825 - 1137440..1138147 (-) 708 WP_011528760.1 O-methyltransferase -
  EW024_RS05830 - 1138213..1139409 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  EW024_RS05835 pepF 1139785..1141590 (-) 1806 WP_002995768.1 oligoendopeptidase F Regulator
  EW024_RS05840 coiA 1141603..1142565 (-) 963 WP_002983995.1 competence protein CoiA Machinery gene
  EW024_RS05845 - 1142860..1143576 (-) 717 WP_011528761.1 pseudouridine synthase -
  EW024_RS05850 nagB 1143695..1144399 (-) 705 WP_021299319.1 glucosamine-6-phosphate deaminase -
  EW024_RS05855 queA 1144601..1145629 (+) 1029 WP_011528763.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  EW024_RS05860 - 1145636..1146856 (+) 1221 WP_011528764.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37801.25 Da        Isoelectric Point: 10.2848

>NTDB_id=994233 EW024_RS05840 WP_002983995.1 1141603..1142565(-) (coiA) [Streptococcus pyogenes strain SP444 isolate SP444]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=994233 EW024_RS05840 WP_002983995.1 1141603..1142565(-) (coiA) [Streptococcus pyogenes strain SP444 isolate SP444]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTTTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCATTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403