Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   EW021_RS09050 Genome accession   NZ_LR130236
Coordinates   1760216..1760812 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain 5448 isolate 5448     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1755216..1765812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW021_RS09015 - 1755277..1755582 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  EW021_RS09020 ruvX 1755594..1756013 (-) 420 WP_010922752.1 Holliday junction resolvase RuvX -
  EW021_RS09025 - 1756010..1756279 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EW021_RS09030 spx 1756392..1756790 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EW021_RS09035 recA 1757081..1758217 (-) 1137 WP_010922753.1 recombinase RecA Machinery gene
  EW021_RS09040 cinA 1758306..1759577 (-) 1272 WP_010922754.1 competence/damage-inducible protein A Machinery gene
  EW021_RS09045 - 1759646..1760206 (-) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  EW021_RS09050 ruvA 1760216..1760812 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  EW021_RS09055 - 1760814..1762034 (-) 1221 WP_010922756.1 MDR family MFS transporter -
  EW021_RS09060 hexB 1762045..1764027 (-) 1983 WP_010922757.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=994173 EW021_RS09050 WP_002992186.1 1760216..1760812(-) (ruvA) [Streptococcus pyogenes strain 5448 isolate 5448]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=994173 EW021_RS09050 WP_002992186.1 1760216..1760812(-) (ruvA) [Streptococcus pyogenes strain 5448 isolate 5448]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419