Detailed information NTG0989494

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HMPREF9425_RS02240
• Genome accession: NZ_GL831112
• Coordinates: 421315..423555 (+)
• Length: 746 a.a.
• NCBI ID: WP_003096429.1
• Uniprot ID: A0ABN0CI33
• Organism: Streptococcus vestibularis ATCC 49124
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 416315..428555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS02210 (HMPREF9425_0462)	-	416726..417235 (+)	510	WP_037621639.1	hypothetical protein	-
HMPREF9425_RS10655	-	417447..417566 (+)	120	Protein_446	IS30 family transposase	-
HMPREF9425_RS02215 (HMPREF9425_0463)	-	417616..417885 (-)	270	WP_003096419.1	GIY-YIG nuclease family protein	-
HMPREF9425_RS02220 (HMPREF9425_0464)	-	417889..418653 (-)	765	WP_003096421.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
HMPREF9425_RS02225 (HMPREF9425_0465)	-	418703..419638 (-)	936	WP_003096423.1	polysaccharide deacetylase family protein	-
HMPREF9425_RS02230 (HMPREF9425_0466)	-	419768..420523 (+)	756	WP_003096426.1	lysophospholipid acyltransferase family protein	-
HMPREF9425_RS02235 (HMPREF9425_0467)	comEA	420630..421325 (+)	696	WP_003093743.1	helix-hairpin-helix domain-containing protein	Machinery gene
HMPREF9425_RS02240 (HMPREF9425_0468)	comEC/celB	421315..423555 (+)	2241	WP_003096429.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HMPREF9425_RS02245 (HMPREF9425_0469)	-	423641..424903 (+)	1263	WP_003093180.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HMPREF9425_RS02250 (HMPREF9425_0470)	-	424969..425514 (+)	546	WP_003093731.1	GNAT family N-acetyltransferase	-
HMPREF9425_RS02255 (HMPREF9425_0471)	spxR	425507..426785 (+)	1279	WP_003094415.1	CBS-HotDog domain-containing transcription factor SpxR	-
HMPREF9425_RS02260 (HMPREF9425_0472)	-	426934..427794 (+)	861	WP_003096442.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84940.88 Da
• Isoelectric Point: 9.8301

>NTDB_id=989494 HMPREF9425_RS02240 WP_003096429.1 421315..423555(+) (comEC/celB) [Streptococcus vestibularis ATCC 49124]
MWLKKSPINLFSLALLIVALYFTIFVSNFYAIGAFVFFMVCFLKHHWKNMAALKLVGLVGGFFLIYFLFLHHRAIMQDKQ
VPAEIHQVTLVADTLSVNGEQLSAIGKSNGQTYRVFYRLKSEKEQYFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQSIYRIAQIERLDHIVTPKSISPIDFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYSLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLLFLV
LPHFLLTVGGVLSCSYAFLLCLFDFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPILT
VLFTLSGLVIFSQINPLFEWMETFLTWIQYWIGQPLILGKPSLFQFGLMIVVLVLLFDFWKKPQFRISLLMIFSLLMIWV
KHPLINEVTVVDVGQGDSIFLRSMKGKTILIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFAKRLRFLKRPVRTLKAGDKLPMMGSNIQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMSSYPNLKVSVLKAGHHGSKGSSSEAFLDQLEPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFKLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=989494 HMPREF9425_RS02240 WP_003096429.1 421315..423555(+) (comEC/celB) [Streptococcus vestibularis ATCC 49124]
ATGTGGCTTAAAAAATCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGGCTTTTGTCTTTTTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATATGGCAGCTCTAA
AGTTGGTGGGACTTGTTGGTGGGTTCTTTTTGATTTATTTTTTATTCTTGCACCACAGAGCTATCATGCAAGATAAGCAA
GTTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCAATTATCAGCAATCGGTAA
GTCAAATGGTCAAACCTATCGGGTCTTTTACCGGTTAAAATCTGAGAAGGAGCAGTATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGAAAAATAAAGCTATCCTCGGCAACAGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGAGCATTTATAGGATTGCTCAGATTGAGCGTCTGGATCATATCGTAACCCCAAAATCGATATCTCCAAT
AGATTTTTTCCATCAATTGAGGAGGAGGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTATATGA
CAGGACTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAGAGTCAACTCTACACCAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTTCGTTTGGGTCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATAGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTTTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTGCTTCTATTATTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTATTGTGTTTATTTGATTTTGAGGA
GATGCCGTCTTTTAAAAAGTCAATCTATATGAGTTTGGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTCGATAGCTTTCTCTTACCTATCTTAACA
GTACTTTTTACACTTTCAGGACTGGTAATCTTTTCTCAAATTAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATACTGGATAGGCCAGCCTTTAATTCTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGATCTGGGTT
AAACATCCTTTGATCAATGAGGTGACGGTGGTTGACGTTGGTCAAGGAGACAGTATTTTTTTAAGGAGTATGAAAGGTAA
GACGATCCTGATAGACGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACAGATACA
GACCATATTGGTGATTTGGAGGAAGTAGCTAAACGGTTTAAGATTAAGGAAATTTGTGTCAGTCAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTCTTCGATTTCTTAAACGTCCCGTTCGCACCTTAAAGGCTGGTGATAAACTGCCTATGATGG
GAAGTAACATACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGGACCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAATTGATGTCCAGCTATCCAAATTTAAA
AGTAAGTGTTCTCAAGGCAGGACATCACGGCTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGTTAGAACCATCAC
TTGCGCTTGTCTCAGCTGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAT
ATTAAGGTTTTACGCACAGACCAGGATGGTGCTATTCGGTTTAAGGGATGGTTCAAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.989	100	0.48
comEC/celB	Streptococcus mitis SK321	47.122	100	0.472
comEC/celB	Streptococcus pneumoniae TIGR4	46.185	100	0.462
comEC/celB	Streptococcus pneumoniae D39	45.917	100	0.46
comEC/celB	Streptococcus pneumoniae Rx1	45.917	100	0.46
comEC/celB	Streptococcus pneumoniae R6	45.917	100	0.46
comEC	Lactococcus lactis subsp. cremoris KW2	44.337	97.051	0.43