Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   HMPREF9319_RS02190 Genome accession   NZ_GL397128
Coordinates   440067..440717 (-) Length   216 a.a.
NCBI ID   WP_003063675.1    Uniprot ID   E0PC71
Organism   Streptococcus equinus ATCC 700338     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 435067..445717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS02160 (HMPREF9319_0438) - 435699..436616 (-) 918 WP_003063660.1 sensor histidine kinase -
  HMPREF9319_RS02165 (HMPREF9319_0439) - 436619..437317 (-) 699 WP_003063663.1 response regulator transcription factor -
  HMPREF9319_RS02170 - 437379..437579 (-) 201 Protein_426 hypothetical protein -
  HMPREF9319_RS02175 (HMPREF9319_0440) - 437619..437819 (-) 201 WP_003063668.1 helix-turn-helix transcriptional regulator -
  HMPREF9319_RS02180 (HMPREF9319_0441) - 437907..438234 (-) 328 Protein_428 conjugal transfer protein -
  HMPREF9319_RS10950 (HMPREF9319_0442) - 438237..438506 (+) 270 Protein_429 sodium transporter -
  HMPREF9319_RS02185 (HMPREF9319_0443) - 438644..439984 (-) 1341 WP_003063674.1 Nramp family divalent metal transporter -
  HMPREF9319_RS02190 (HMPREF9319_0444) cclA/cilC 440067..440717 (-) 651 WP_003063675.1 prepilin peptidase Machinery gene
  HMPREF9319_RS02195 (HMPREF9319_0445) - 440847..441377 (+) 531 WP_003063677.1 Dps family protein -
  HMPREF9319_RS02200 (HMPREF9319_0446) - 441744..441953 (+) 210 WP_012961615.1 YqgQ family protein -
  HMPREF9319_RS02205 (HMPREF9319_0447) - 441946..442914 (+) 969 WP_003063681.1 ROK family glucokinase -
  HMPREF9319_RS02210 (HMPREF9319_0448) - 442925..443305 (+) 381 WP_003063685.1 rhodanese-like domain-containing protein -
  HMPREF9319_RS02215 (HMPREF9319_0449) - 443320..444366 (+) 1047 WP_003063687.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 24882.84 Da        Isoelectric Point: 6.0630

>NTDB_id=989386 HMPREF9319_RS02190 WP_003063675.1 440067..440717(-) (cclA/cilC) [Streptococcus equinus ATCC 700338]
MDILLFFFLGASIASFLSLIVDRFPEKSIIFPASHCDSCGKQLAIRDLIPIFSQLINHSRCRFCHTKIPFWYGLLELYFG
VIVVLYYCALLSLDQVFILFFSTTLSLYDLKRQEFPLLIWLLPSIFLLFVTPINALAIILLAFGIMAELIDLKIGSGDFF
YLASLSLLLDVQTILWIIELGSLSGIIYYFFQTNKRIPFVPFLFLGYLILFIFNHD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=989386 HMPREF9319_RS02190 WP_003063675.1 440067..440717(-) (cclA/cilC) [Streptococcus equinus ATCC 700338]
ATGGACATTTTATTATTCTTTTTTCTAGGGGCTTCTATTGCTTCTTTTCTCAGTTTAATCGTTGATCGATTTCCTGAAAA
ATCAATCATTTTTCCTGCCAGTCACTGTGATTCTTGTGGAAAACAACTTGCCATTCGTGATTTGATTCCTATTTTTTCTC
AACTGATAAATCATTCACGTTGTCGTTTTTGCCACACCAAAATTCCTTTCTGGTATGGACTGTTAGAACTTTATTTTGGG
GTCATTGTCGTACTTTACTATTGCGCACTTCTCTCACTCGACCAAGTTTTTATCTTGTTTTTTAGCACAACGCTTAGTCT
TTATGACTTGAAACGTCAAGAGTTTCCATTGTTGATTTGGCTCCTTCCAAGTATTTTTTTGCTTTTTGTCACGCCGATTA
ATGCGCTAGCTATTATTCTTTTGGCTTTTGGGATAATGGCAGAGCTGATTGATTTGAAAATCGGTAGCGGTGATTTTTTC
TACCTTGCCAGTTTGAGTCTGCTTCTTGACGTTCAAACCATTTTATGGATTATCGAACTTGGCTCTCTTTCAGGTATTAT
TTACTACTTTTTCCAGACAAATAAACGAATTCCCTTTGTGCCATTTTTGTTTTTAGGATATCTGATTTTATTCATTTTTA
ACCATGATTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PC71

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

45.631

95.37

0.435
  cclA/cilC Streptococcus pneumoniae TIGR4

45.545

93.519

0.426
  cclA/cilC Streptococcus pneumoniae Rx1

44.66

95.37

0.426
  cclA/cilC Streptococcus pneumoniae D39

44.66

95.37

0.426
  cclA/cilC Streptococcus pneumoniae R6

44.66

95.37

0.426
  cclA/cilC Streptococcus mitis NCTC 12261

43.689

95.37

0.417