Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   AAFQ93_RS06055 Genome accession   NZ_CP152419
Coordinates   1274585..1275934 (+) Length   449 a.a.
NCBI ID   WP_223140896.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1269585..1280934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS06035 (AAFQ93_06020) - 1269722..1270192 (-) 471 WP_001030117.1 arginine repressor -
  AAFQ93_RS06040 (AAFQ93_06025) - 1270143..1272482 (-) 2340 WP_375554924.1 Xaa-Pro dipeptidyl-peptidase -
  AAFQ93_RS06045 (AAFQ93_06030) mutY 1272660..1273823 (+) 1164 WP_375554925.1 A/G-specific adenine glycosylase -
  AAFQ93_RS06050 (AAFQ93_06035) micA 1273888..1274592 (+) 705 WP_000722070.1 response regulator YycF Regulator
  AAFQ93_RS06055 (AAFQ93_06040) micB 1274585..1275934 (+) 1350 WP_223140896.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AAFQ93_RS06060 (AAFQ93_06045) vicX 1275936..1276745 (+) 810 WP_045763287.1 MBL fold metallo-hydrolase Regulator
  AAFQ93_RS06065 (AAFQ93_06050) relB 1276835..1277077 (+) 243 WP_223140897.1 type II toxin-antitoxin system RelB family antitoxin -
  AAFQ93_RS06070 (AAFQ93_06055) - 1277079..1277333 (+) 255 WP_045763285.1 type II toxin-antitoxin system RelE/ParE family toxin -
  AAFQ93_RS06075 (AAFQ93_06060) - 1277386..1278159 (+) 774 WP_223140898.1 potassium channel family protein -
  AAFQ93_RS06080 (AAFQ93_06065) - 1278296..1278643 (-) 348 WP_049508487.1 thiol reductase thioredoxin -
  AAFQ93_RS06085 (AAFQ93_06070) - 1278883..1280601 (-) 1719 WP_375554926.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51616.07 Da        Isoelectric Point: 4.6449

>NTDB_id=989177 AAFQ93_RS06055 WP_223140896.1 1274585..1275934(+) (micB) [Streptococcus nidrosiense strain SO-23-1]
MIEVIKQTILTSDFIFILILIGFIMLVTFLLLESRRDNIRLRQLNQKVKDLIAGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQIIMINDMAKRQLGVERDDALNQNILELLKIEEEYELRDLITQSPE
LMIYSQNVNGEYISLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSISDQGLGIPKEDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDELED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=989177 AAFQ93_RS06055 WP_223140896.1 1274585..1275934(+) (micB) [Streptococcus nidrosiense strain SO-23-1]
ATGATTGAAGTAATTAAACAAACAATTTTGACGAGTGACTTTATCTTTATCCTCATCCTAATTGGCTTTATTATGCTGGT
GACTTTTCTTTTGCTTGAGAGCCGTCGTGATAATATTCGCCTTAGACAGCTAAACCAGAAGGTTAAGGATTTGATTGCTG
GTGATTATTCTCAGGTTTTGGATATGCAGGGAAGCTCAGAGATAACTAATATCACTAACAATCTTAATGATTTGTCAGAA
GTAATCCGTTTGACTCAAGAAAATCTGGAACAAGAGAGTAAAAGGTTGAATAGTATCTTGTCCTACATGACAGACGGAGT
ACTTGCGACCAATCGTCGTGGTCAGATTATCATGATTAATGATATGGCTAAGAGACAACTTGGAGTTGAAAGGGATGATG
CTCTTAATCAAAATATCTTAGAGTTACTCAAGATTGAAGAAGAGTATGAGCTGAGAGATCTCATTACCCAAAGTCCTGAA
TTGATGATTTATTCGCAAAATGTGAATGGGGAGTATATCAGCTTGCGCGTGCGTTTTGCCTTGATTCGTAGAGAGTCTGG
CTTTATCTCTGGTTTAGTAGCAGTTCTACATGATACAACTGAACAAGAGAAGGAAGAACGAGAGAGAAGGCTTTTTGTTT
CGAACGTTAGTCATGAGTTGCGTACACCTTTGACCAGTGTAAAATCCTATCTTGAGGCCTTGGATGAAGGAGCTCTTACA
GAACCGGTTGCTCCAGACTTTATCAAGGTTTCTCTGGATGAAACCAACCGTATGATGCGGATGGTGACGGACCTCTTGCA
TCTTTCACGGATTGACAATGCAACTAGTCACTTAGATGTTGAATTGATTAATTTTACGGCCTTTATCACTTTTATCCTTA
ATCGTTTTGATAAAATGAAAAGTCAGGATGAGGAGAAGAAGTACGAGTTGGTGAGAGATTATCCGATTAACTCTGTTTGG
ATTGAGATTGATACGGATAAGATGACCCAGGTGATTGATAATATTTTAAATAATGCTATCAAGTATTCACCAGATGGTGG
AAAAATCACTGTAAGCATGAAGACTACAGATGATCAGATGATTTTATCAATTTCGGACCAAGGGCTTGGGATTCCTAAAG
AAGATCTACCAAAGATTTTTGACCGTTTTTATCGTGTTGACAAGGCAAGAAGTCGTGCTCAAGGTGGTACTGGTCTAGGA
CTTGCTATTGCTAAAGAAATCGTCAAACAACATAAGGGATTTATCTGGGCTAAGAGTGAATACGGTAAGGGTTCAACCTT
TACTATCGTACTGCCATACGATAAGGATGCCGTGAAAGAAGAGATTTGGGAGGATGAACTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

88.383

97.773

0.864
  vicK Streptococcus mutans UA159

72.019

91.537

0.659

Multiple sequence alignment