Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   AAHH81_RS10225 Genome accession   NZ_CP152418
Coordinates   1997251..1997913 (-) Length   220 a.a.
NCBI ID   WP_061813445.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20234287     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1992251..2002913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAHH81_RS10200 (AAHH81_10185) - 1992402..1992668 (-) 267 WP_001278167.1 Veg family protein -
  AAHH81_RS10205 (AAHH81_10190) dnaB 1992670..1994022 (-) 1353 WP_050137283.1 replicative DNA helicase -
  AAHH81_RS10210 (AAHH81_10195) rplI 1994065..1994517 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  AAHH81_RS10215 (AAHH81_10200) - 1994514..1996487 (-) 1974 WP_374918025.1 DHH family phosphoesterase -
  AAHH81_RS10220 (AAHH81_10205) hpf 1996623..1997171 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  AAHH81_RS10225 (AAHH81_10210) comFC/cflB 1997251..1997913 (-) 663 WP_061813445.1 ComF family protein Machinery gene
  AAHH81_RS10230 (AAHH81_10215) comFA/cflA 1997910..1999208 (-) 1299 WP_000867609.1 DEAD/DEAH box helicase Machinery gene
  AAHH81_RS10235 (AAHH81_10220) - 1999264..1999899 (+) 636 WP_000395739.1 YigZ family protein -
  AAHH81_RS10240 (AAHH81_10225) cysK 2000184..2001104 (+) 921 WP_000029866.1 cysteine synthase A -
  AAHH81_RS10245 (AAHH81_10230) - 2001343..2001693 (-) 351 Protein_1977 IS66 family transposase -
  AAHH81_RS10250 (AAHH81_10235) - 2001693..2001985 (+) 293 Protein_1978 transposase -
  AAHH81_RS10255 (AAHH81_10240) tnpB 2002126..2002341 (-) 216 WP_000376916.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25275.11 Da        Isoelectric Point: 7.3688

>NTDB_id=989114 AAHH81_RS10225 WP_061813445.1 1997251..1997913(-) (comFC/cflB) [Streptococcus pneumoniae strain 20234287]
MKCLLCGQTMKTVLTFSSLLFLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=989114 AAHH81_RS10225 WP_061813445.1 1997251..1997913(-) (comFC/cflB) [Streptococcus pneumoniae strain 20234287]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTATTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment