Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8568_RS10600 Genome accession   NZ_AP026931
Coordinates   2072356..2073018 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain PZ900701541     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2067356..2078018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8568_RS10575 (PC1520_20470) - 2067506..2067772 (-) 267 WP_001278167.1 Veg family protein -
  R8568_RS10580 (PC1520_20480) dnaB 2067774..2069126 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8568_RS10585 (PC1520_20490) rplI 2069170..2069622 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8568_RS10590 (PC1520_20500) - 2069619..2071592 (-) 1974 WP_000715129.1 DHH family phosphoesterase -
  R8568_RS10595 (PC1520_20510) hpf 2071728..2072276 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8568_RS10600 (PC1520_20520) comFC/cflB 2072356..2073018 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  R8568_RS10605 (PC1520_20530) comFA/cflA 2073015..2074313 (-) 1299 WP_000867610.1 DEAD/DEAH box helicase Machinery gene
  R8568_RS10610 (PC1520_20540) - 2074369..2075004 (+) 636 WP_000395739.1 YigZ family protein -
  R8568_RS10615 (PC1520_20550) cysK 2075289..2076209 (+) 921 WP_000029862.1 cysteine synthase A -
  R8568_RS10620 - 2076448..2076822 (-) 375 Protein_2055 IS66 family transposase -
  R8568_RS10625 - 2076795..2076970 (+) 176 Protein_2056 transposase -
  R8568_RS10630 (PC1520_20570) tnpB 2077072..2077287 (-) 216 WP_000376907.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=98861 R8568_RS10600 WP_000649971.1 2072356..2073018(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900701541]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=98861 R8568_RS10600 WP_000649971.1 2072356..2073018(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900701541]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment