Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   KNP07_RS24435 Genome accession   NZ_CP152075
Coordinates   5246409..5247746 (+) Length   445 a.a.
NCBI ID   WP_217385353.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain NCTR 501     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5241409..5252746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KNP07_RS24410 (KNP07_24415) pgeF 5241552..5242280 (-) 729 WP_134279339.1 peptidoglycan editing factor PgeF -
  KNP07_RS24415 (KNP07_24420) rluD 5242277..5243239 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  KNP07_RS24420 (KNP07_24425) - 5243385..5244410 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  KNP07_RS24425 (KNP07_24430) - 5244567..5244812 (+) 246 WP_014603563.1 PP0621 family protein -
  KNP07_RS24430 (KNP07_24435) pilS 5244802..5246394 (+) 1593 WP_003110428.1 two-component system sensor histidine kinase PilS Regulator
  KNP07_RS24435 (KNP07_24440) pilR 5246409..5247746 (+) 1338 WP_217385353.1 two-component system response regulator PilR Regulator
  KNP07_RS24440 (KNP07_24445) thiO 5247792..5248886 (-) 1095 WP_049270875.1 glycine oxidase ThiO -
  KNP07_RS24445 (KNP07_24450) - 5249021..5249530 (+) 510 WP_023088572.1 Tfp pilus assembly protein FimT/FimU -
  KNP07_RS24450 (KNP07_24455) - 5249636..5250142 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  KNP07_RS24455 (KNP07_24460) pilV 5250133..5250690 (+) 558 WP_003110422.1 type 4a pilus minor pilin PilV Machinery gene
  KNP07_RS24460 (KNP07_24465) pilW 5250687..5251511 (+) 825 WP_003119422.1 type 4a pilus minor pilin PilW -
  KNP07_RS24465 (KNP07_24470) pilX 5251508..5252095 (+) 588 WP_003094700.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49665.00 Da        Isoelectric Point: 6.1219

>NTDB_id=987211 KNP07_RS24435 WP_217385353.1 5246409..5247746(+) (pilR) [Pseudomonas aeruginosa strain NCTR 501]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLGTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLADRI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=987211 KNP07_RS24435 WP_217385353.1 5246409..5247746(+) (pilR) [Pseudomonas aeruginosa strain NCTR 501]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGGCACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCTACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGATCGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCAGGCAACGTCCGCGAGCTGGAGAATATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGAACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.551

100

0.996
  pilR Acinetobacter baumannii strain A118

50.98

100

0.526
  luxO Vibrio cholerae strain A1552

37.946

100

0.382

Multiple sequence alignment