Detailed information NTG0986343

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACOCJC_RS10275
• Genome accession: NZ_CP184549
• Coordinates: 2073171..2073944 (-)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain SCTW2019145
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 2068171..2078944

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJC_RS10240 (ACOCJC_10240)	-	2068425..2069195 (-)	771	WP_000473705.1	isoprenyl transferase	-
ACOCJC_RS10245 (ACOCJC_10245)	frr	2069568..2070122 (-)	555	WP_001280006.1	ribosome recycling factor	-
ACOCJC_RS10250 (ACOCJC_10250)	pyrH	2070141..2070863 (-)	723	WP_000057330.1	UMP kinase	-
ACOCJC_RS10255 (ACOCJC_10255)	tsf	2071000..2071881 (-)	882	WP_000201387.1	translation elongation factor Ts	-
ACOCJC_RS10260 (ACOCJC_10260)	-	2071916..2072028 (-)	113	Protein_1976	hypothetical protein	-
ACOCJC_RS10265 (ACOCJC_10265)	rpsB	2072062..2072829 (-)	768	WP_000268484.1	30S ribosomal protein S2	-
ACOCJC_RS10270 (ACOCJC_10270)	-	2073028..2073120 (-)	93	WP_001790530.1	hypothetical protein	-
ACOCJC_RS10275 (ACOCJC_10275)	codY	2073171..2073944 (-)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACOCJC_RS10280 (ACOCJC_10280)	hslU	2073969..2075372 (-)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACOCJC_RS10285 (ACOCJC_10285)	hslV	2075438..2075983 (-)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACOCJC_RS10290 (ACOCJC_10290)	xerC	2075980..2076876 (-)	897	WP_001015606.1	tyrosine recombinase XerC	-
ACOCJC_RS10295 (ACOCJC_10295)	trmFO	2077293..2078600 (-)	1308	WP_158109038.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=986343 ACOCJC_RS10275 WP_000055337.1 2073171..2073944(-) (codY) [Staphylococcus aureus strain SCTW2019145]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=986343 ACOCJC_RS10275 WP_000055337.1 2073171..2073944(-) (codY) [Staphylococcus aureus strain SCTW2019145]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTTATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAG

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428