Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NST80_RS04305 Genome accession   NZ_CP152039
Coordinates   975295..976710 (+) Length   471 a.a.
NCBI ID   WP_118171861.1    Uniprot ID   -
Organism   Streptococcus sp. FSL K6-1323     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 970295..981710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS04280 (NST80_04280) - 970746..971318 (-) 573 WP_084871334.1 ECF transporter S component -
  NST80_RS04285 (NST80_04285) coaC 971347..971892 (-) 546 WP_084871335.1 phosphopantothenoylcysteine decarboxylase -
  NST80_RS04290 (NST80_04290) - 971885..972568 (-) 684 WP_084871336.1 phosphopantothenate--cysteine ligase -
  NST80_RS04295 (NST80_04295) - 972762..974432 (+) 1671 WP_118171862.1 formate--tetrahydrofolate ligase -
  NST80_RS04300 (NST80_04300) ciaR 974631..975305 (+) 675 WP_002891134.1 response regulator transcription factor Regulator
  NST80_RS04305 (NST80_04305) ciaH 975295..976710 (+) 1416 WP_118171861.1 HAMP domain-containing sensor histidine kinase Regulator
  NST80_RS04310 (NST80_04310) rpsT 976788..977024 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  NST80_RS04315 (NST80_04315) coaA 977094..978014 (-) 921 WP_022496694.1 type I pantothenate kinase -
  NST80_RS04320 (NST80_04320) - 978127..978717 (+) 591 WP_014633038.1 class I SAM-dependent methyltransferase -
  NST80_RS04325 (NST80_04325) - 978714..979991 (+) 1278 WP_342504647.1 pyrimidine-nucleoside phosphorylase -
  NST80_RS04330 (NST80_04330) deoC 980025..980687 (+) 663 WP_022496692.1 deoxyribose-phosphate aldolase -
  NST80_RS04335 (NST80_04335) - 980674..981072 (+) 399 WP_118171859.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53485.24 Da        Isoelectric Point: 8.7696

>NTDB_id=986320 NST80_RS04305 WP_118171861.1 975295..976710(+) (ciaH) [Streptococcus sp. FSL K6-1323]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAAAKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDNKESTAETPDSSGSKKEPKKKSRIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPINTDKTLLKQLMTILFDNAIKYTEEDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=986320 NST80_RS04305 WP_118171861.1 975295..976710(+) (ciaH) [Streptococcus sp. FSL K6-1323]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTTTGAGTTACGGCGTTTATTCCAATGTGGACTCAA
GTCTTAAAATGGCAGCCGCTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATAATAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAGAATTGAAGATGCCCCTCACGATTTATCTGTTGCGGCAAACACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACAGAAAAGTACCGTCTGATTACTGAGAAAGT
AGACAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGCACGCCACTTGC
AGTTATCCAAAACCGTTTAGAAGTTCTTTTCCGAAAACCTGAGAGCACCATTTTAGATAATTCTGAGAATATCGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTTTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTAGGTCGTCCAATAAATACTGATAAAACACTGTTGAAACAGTTAATGACTATTTTATTTG
ATAATGCTATCAAATATACGGAAGAGGATGGACATGTGACCTTTACTGTCCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.304

97.665

0.55
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment