Detailed information NTG0985488

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: ACLB5D_RS10890
• Genome accession: NZ_CP184143
• Coordinates: 2153143..2154381 (-)
• Length: 412 a.a.
• NCBI ID: WP_000815968.1
• Uniprot ID: -
• Organism: Escherichia coli strain F11
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2148143..2159381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLB5D_RS10870	dam	2148755..2149591 (-)	837	WP_000742143.1	adenine-specific DNA-methyltransferase	-
ACLB5D_RS10875	damX	2149698..2150984 (-)	1287	WP_000343193.1	cell division protein DamX	-
ACLB5D_RS10880	aroB	2151076..2152164 (-)	1089	WP_000439846.1	3-dehydroquinate synthase	-
ACLB5D_RS10885	aroK	2152221..2152742 (-)	522	WP_000818618.1	shikimate kinase AroK	-
ACLB5D_RS10890	comE	2153143..2154381 (-)	1239	WP_000815968.1	DNA uptake porin HofQ	Machinery gene
ACLB5D_RS10895	hofP	2154293..2154697 (-)	405	WP_001300917.1	DNA utilization protein HofP	-
ACLB5D_RS10900	hofO	2154687..2155127 (-)	441	WP_001055763.1	DNA utilization protein HofO	-
ACLB5D_RS10905	hofN	2155111..2155650 (-)	540	Protein_2133	DNA utilization protein HofN	-
ACLB5D_RS10910	hofM	2155650..2156429 (-)	780	WP_001297394.1	DNA utilization protein HofM	-
ACLB5D_RS10915	mrcA	2156549..2159101 (+)	2553	WP_000673804.1	peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA	-

Sequence

Protein

• Length: 412 a.a.
• Molecular weight: 44774.27 Da
• Isoelectric Point: 6.1173

>NTDB_id=985488 ACLB5D_RS10890 WP_000815968.1 2153143..2154381(-) (comE) [Escherichia coli strain F11]
MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGL
ITRQEDNILSVHSIAWQNNNIARQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNIGRIN
GRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKL
HISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERREL
VVFITPRLVSSE

Nucleotide

• Length: 1239 bp

>NTDB_id=985488 ACLB5D_RS10890 WP_000815968.1 2153143..2154381(-) (comE) [Escherichia coli strain F11]
ATGAAGCAATGGATAGCCGCACTACTGTTGATGCTGATACCCGGCGTACAGGCGGCAAAGCCGCAAAAAGTGACGCTGAT
GGTGGATGACGTTCCGGTAGCTCAGGTGTTGCAGGCGCTGGCTGAACAGGAGAAGTTGAACCTGGTCGTGTCGCCAGACG
TCAGCGGTACGGTGTCGTTACATCTAACAGATGTTCCCTGGAAGCAGGCACTACAAACTGTAGTGAAAAGCGCCGGACTG
ATAACGCGGCAGGAAGACAACATTCTCTCAGTGCATTCCATTGCCTGGCAGAATAACAATATCGCCCGCCAGGAGGCGGA
GCAGGCGCGGGCGCAGGCAAATCTGCCGCTGGAAAATCGCAGTATAACCCTGCAATACGCCGACGCGGGAGAACTGGCGA
AAGCGGGGGAGAAGCTACTGAGTGCCAAAGGGAGTATGACCGTCGATAAACGCACCAATCGCCTTTTGCTACGAGATAAC
AAAACGGCGTTAAGCGCGCTTGAACAGTGGGTAGCGCAAATGGATCTGCCGGTCGGGCAGGTTGAGCTGTCGGCGCATAT
TGTCACCATTAATGAAAAAAGTTTGCGTGAGTTAGGCGTGAAATGGACGCTGGCCGATGCGCAACACGCTGGTGGCGTTG
GGCAAGTCACCACGCTTGGTAGCGACCTCTCCGTAGCGACGGCGACAACGCATGTCGGTTTTAACATTGGGCGCATCAAC
GGACGCTTGCTGGATCTTGAGCTTTCTGCGCTCGAACAAAAACAGCAGCTGGATATTATCGCCAGTCCGCGTCTGCTGGC
CTCACATCTTCAGCCTGCCAGCATTAAACAGGGGAGCGAAATTCCATATCAGGTTTCCAGCGGGGAAAGTGGCGCGACGT
CGGTGGAATTTAAAGAGGCCGTCCTGGGGATGGAGGTCACGCCCACGGTGTTACAAAAAGGTCGCATCCGGCTGAAATTA
CACATCAGCCAGAACGTTCCGGGGCAGGTGCTACAGCAGGCCGATGGCGAAGTGCTGGCGATTGATAAGCAGGAGATCGA
AACGCAGGTCGAGGTCAAAAGCGGAGAAACGTTGGCGCTGGGCGGCATTTTTACCCGTAAAAATAAATCGGGTCAGGATA
GCGTACCGTTGCTTGGCGACATTCCCTGGTTCGGGCAATTATTTCGTCATGACGGAAAAGAAGATGAACGACGCGAGTTA
GTGGTGTTTATCACGCCACGACTGGTTTCCAGTGAGTAA

Domains

Predicted by InterProScan.

• Bacterial type II and III secretion system protein (Secretin) (250-409)

• Bacterial type II/III secretion system short domain (Secretin_N) (120-179)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	37.385	100	0.396
comE	Haemophilus influenzae 86-028NP	37.156	100	0.393
pilQ	Vibrio campbellii strain DS40M4	37.767	100	0.386
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	37.288	100	0.374
pilQ	Vibrio cholerae strain A1552	37.288	100	0.374
comE	Glaesserella parasuis strain SC1401	35.952	100	0.367