Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R8611_RS08295 Genome accession   NZ_AP026927
Coordinates   1646248..1646907 (+) Length   219 a.a.
NCBI ID   WP_050199627.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1641248..1651907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS08275 (PC0174_16410) - 1641885..1642781 (-) 897 WP_000825665.1 PEP phosphonomutase -
  R8611_RS08280 (PC0174_16420) - 1642784..1644046 (-) 1263 WP_317647902.1 PTS sugar transporter subunit IIC -
  R8611_RS08285 (PC0174_16430) - 1644326..1645504 (+) 1179 WP_000175882.1 ROK family transcriptional regulator -
  R8611_RS08290 (PC0174_16440) - 1645732..1646178 (-) 447 WP_000155433.1 GNAT family N-acetyltransferase -
  R8611_RS08295 (PC0174_16450) cclA/cilC 1646248..1646907 (+) 660 WP_050199627.1 A24 family peptidase Machinery gene
  R8611_RS08300 (PC0174_16460) - 1646959..1648110 (-) 1152 WP_081509593.1 XRE family transcriptional regulator -
  R8611_RS08305 (PC0174_16470) - 1648125..1648856 (-) 732 WP_000934017.1 hypothetical protein -
  R8611_RS08310 - 1649076..1649186 (+) 111 Protein_1651 prepilin peptidase -
  R8611_RS08315 (PC0174_16480) trpA 1649158..1649934 (-) 777 WP_317647904.1 tryptophan synthase subunit alpha -
  R8611_RS08320 (PC0174_16490) trpB 1649927..1651150 (-) 1224 WP_024477621.1 tryptophan synthase subunit beta -
  R8611_RS08325 (PC0174_16500) - 1651128..1651727 (-) 600 WP_050199625.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24846.95 Da        Isoelectric Point: 7.2171

>NTDB_id=98518 R8611_RS08295 WP_050199627.1 1646248..1646907(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700178]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHYQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=98518 R8611_RS08295 WP_050199627.1 1646248..1646907(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700178]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACTATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment