Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   R8611_RS02420 Genome accession   NZ_AP026927
Coordinates   478535..479272 (+) Length   245 a.a.
NCBI ID   WP_001219137.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700178     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 473535..484272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8611_RS02390 (PC0174_04690) - 474866..475153 (-) 288 WP_000777760.1 hypothetical protein -
  R8611_RS02395 (PC0174_04700) - 475163..475573 (-) 411 WP_001278301.1 HIT family protein -
  R8611_RS02400 (PC0174_04710) pptA 475641..476372 (+) 732 WP_001866897.1 ABC transporter ATP-binding protein Regulator
  R8611_RS02405 (PC0174_04720) - 476369..477418 (+) 1050 WP_001866896.1 ABC transporter permease -
  R8611_RS02410 (PC0174_04730) - 477586..477915 (-) 330 WP_000132572.1 hypothetical protein -
  R8611_RS02415 (PC0174_04740) - 478192..478530 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  R8611_RS02420 (PC0174_04750) comE/blpR 478535..479272 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  R8611_RS02425 (PC0174_04760) - 479286..480626 (+) 1341 WP_001099893.1 sensor histidine kinase -
  R8611_RS02430 (PC0174_04770) blpC 480670..480825 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  R8611_RS02435 (PC0174_04780) - 480882..482243 (-) 1362 WP_033705510.1 bacteriocin secretion accessory protein -
  R8611_RS02440 (PC0174_04790) comA/nlmT 482254..483930 (-) 1677 WP_307774337.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28768.92 Da        Isoelectric Point: 6.2366

>NTDB_id=98491 R8611_RS02420 WP_001219137.1 478535..479272(+) (comE/blpR) [Streptococcus pneumoniae strain PZ900700178]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=98491 R8611_RS02420 WP_001219137.1 478535..479272(+) (comE/blpR) [Streptococcus pneumoniae strain PZ900700178]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment