Detailed information NTG0098343

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8507_RS04830
• Genome accession: NZ_AP026925
• Coordinates: 940937..941890 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain PZ900700097
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 935937..946890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8507_RS04805	rpmG	936680..936829 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R8507_RS04810 (PC0094_09400)	secG	936869..937102 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8507_RS04815 (PC0094_09410)	rnr	937204..939558 (+)	2355	WP_000654872.1	ribonuclease R	-
R8507_RS04820 (PC0094_09420)	smpB	939521..939988 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8507_RS04825 (PC0094_09430)	tehB	940004..940864 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R8507_RS04830 (PC0094_09440)	coiA	940937..941890 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R8507_RS04835 (PC0094_09450)	pepF	941909..943711 (+)	1803	WP_044812612.1	oligoendopeptidase F	Regulator
R8507_RS04840 (PC0094_09460)	-	943713..944426 (+)	714	WP_078102909.1	O-methyltransferase	-
R8507_RS04845 (PC0094_09470)	prsA	944493..945434 (+)	942	WP_000727952.1	peptidylprolyl isomerase PrsA	-
R8507_RS04850 (PC0094_09480)	-	945550..945891 (-)	342	Protein_960	transposase	-
R8507_RS04855	-	946307..946402 (+)	96	Protein_961	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=98343 R8507_RS04830 WP_000495909.1 940937..941890(+) (coiA) [Streptococcus pneumoniae strain PZ900700097]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=98343 R8507_RS04830 WP_000495909.1 940937..941890(+) (coiA) [Streptococcus pneumoniae strain PZ900700097]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTGTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435