Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8635_RS11340 Genome accession   NZ_AP026924
Coordinates   2185983..2186645 (-) Length   220 a.a.
NCBI ID   WP_050201094.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2180983..2191645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS11315 (PC0062_21980) - 2181133..2181399 (-) 267 WP_001278167.1 Veg family protein -
  R8635_RS11320 (PC0062_21990) dnaB 2181401..2182753 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8635_RS11325 (PC0062_22000) rplI 2182797..2183249 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8635_RS11330 (PC0062_22010) - 2183246..2185219 (-) 1974 WP_044790958.1 DHH family phosphoesterase -
  R8635_RS11335 (PC0062_22020) hpf 2185355..2185903 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8635_RS11340 (PC0062_22030) comFC/cflB 2185983..2186645 (-) 663 WP_050201094.1 ComF family protein Machinery gene
  R8635_RS11345 (PC0062_22040) comFA/cflA 2186642..2187940 (-) 1299 WP_000867608.1 DEAD/DEAH box helicase Machinery gene
  R8635_RS11350 (PC0062_22050) - 2187996..2188631 (+) 636 WP_000395739.1 YigZ family protein -
  R8635_RS11355 (PC0062_22060) cysK 2188916..2189836 (+) 921 WP_000029860.1 cysteine synthase A -
  R8635_RS11360 - 2189911..2190449 (-) 539 Protein_2207 transposase -
  R8635_RS11365 (PC0062_22080) - 2190422..2190730 (+) 309 Protein_2208 transposase -
  R8635_RS11370 (PC0062_22090) tnpB 2190871..2191194 (-) 324 WP_000973416.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25271.12 Da        Isoelectric Point: 7.3688

>NTDB_id=98313 R8635_RS11340 WP_050201094.1 2185983..2186645(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700063]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEATGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=98313 R8635_RS11340 WP_050201094.1 2185983..2186645(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700063]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAACAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(152-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment