Detailed information NTG0098247

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: R8635_RS02335
• Genome accession: NZ_AP026924
• Coordinates: 430203..430862 (-)
• Length: 219 a.a.
• NCBI ID: WP_000565027.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700063
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	431606..439899	430203..430862	flank	744

Gene organization within MGE regions

Location: 430203..439899

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8635_RS02335	cclA/cilC	430203..430862 (-)	660	WP_000565027.1	A24 family peptidase	Machinery gene
R8635_RS02340 (PC0062_04580)	-	430932..431378 (+)	447	WP_000155408.1	GNAT family N-acetyltransferase	-
R8635_RS02345 (PC0062_04590)	-	431606..432784 (-)	1179	WP_000175880.1	ROK family transcriptional regulator	-
R8635_RS02350 (PC0062_04600)	-	433064..434326 (+)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
R8635_RS02355 (PC0062_04610)	-	434329..435225 (+)	897	WP_000825667.1	PEP phosphonomutase	-
R8635_RS02360 (PC0062_04620)	-	435240..435557 (+)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
R8635_RS02365 (PC0062_04630)	-	435574..435891 (+)	318	WP_001005885.1	PTS lactose/cellobiose transporter subunit IIA	-
R8635_RS02370 (PC0062_04640)	-	435901..437256 (+)	1356	WP_001094996.1	PTS sugar transporter subunit IIC	-
R8635_RS02375 (PC0062_04650)	-	437579..439054 (+)	1476	WP_000250870.1	arylsulfatase	-
R8635_RS02380 (PC0062_04660)	-	439051..439899 (+)	849	WP_000782429.1	formylglycine-generating enzyme family protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24855.00 Da
• Isoelectric Point: 7.2564

>NTDB_id=98247 R8635_RS02335 WP_000565027.1 430203..430862(-) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700063]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=98247 R8635_RS02335 WP_000565027.1 430203..430862(-) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700063]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGTCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAGTTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae D39	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae R6	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.845	100	0.858