Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8625_RS10780 Genome accession   NZ_AP026923
Coordinates   2066330..2066992 (-) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2061330..2071992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS10755 (PC0054_20790) - 2061480..2061746 (-) 267 WP_001278167.1 Veg family protein -
  R8625_RS10760 (PC0054_20800) dnaB 2061748..2063100 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8625_RS10765 (PC0054_20810) rplI 2063144..2063596 (-) 453 WP_044790959.1 50S ribosomal protein L9 -
  R8625_RS10770 (PC0054_20820) - 2063593..2065566 (-) 1974 WP_000715111.1 DHH family phosphoesterase -
  R8625_RS10775 (PC0054_20830) hpf 2065702..2066250 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8625_RS10780 (PC0054_20840) comFC/cflB 2066330..2066992 (-) 663 WP_000649974.1 ComF family protein Machinery gene
  R8625_RS10785 (PC0054_20850) comFA/cflA 2066989..2068287 (-) 1299 WP_000867605.1 DEAD/DEAH box helicase Machinery gene
  R8625_RS10790 (PC0054_20860) - 2068343..2068978 (+) 636 WP_000395739.1 YigZ family protein -
  R8625_RS10795 (PC0054_20870) cysK 2069263..2070183 (+) 921 WP_000029866.1 cysteine synthase A -
  R8625_RS10800 - 2070258..2070796 (-) 539 Protein_2086 transposase -
  R8625_RS10805 (PC0054_20890) - 2070769..2071056 (+) 288 Protein_2087 transposase -
  R8625_RS10810 (PC0054_20900) tnpB 2071256..2071534 (-) 279 WP_317649194.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=98231 R8625_RS10780 WP_000649974.1 2066330..2066992(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700054]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=98231 R8625_RS10780 WP_000649974.1 2066330..2066992(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700054]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGTTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAATTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment