Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE/cglE   Type   Machinery gene
Locus tag   R8625_RS09585 Genome accession   NZ_AP026923
Coordinates   1847718..1848020 (-) Length   100 a.a.
NCBI ID   WP_317649158.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1842718..1853020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS09550 (PC0054_18580) rnpA 1843398..1843769 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8625_RS09555 - 1843786..1843917 (-) 132 WP_000768904.1 hypothetical protein -
  R8625_RS09560 (PC0054_18590) - 1843918..1845108 (-) 1191 WP_000167769.1 acetate kinase -
  R8625_RS09565 (PC0054_18600) comYH 1845159..1846112 (-) 954 WP_317649157.1 class I SAM-dependent methyltransferase Machinery gene
  R8625_RS09570 - 1846173..1846767 (-) 595 Protein_1857 class I SAM-dependent methyltransferase -
  R8625_RS09575 (PC0054_18630) comGG/cglG 1846870..1847316 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8625_RS09580 (PC0054_18640) comGF/cglF 1847294..1847755 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8625_RS09585 (PC0054_18650) comGE/cglE 1847718..1848020 (-) 303 WP_317649158.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8625_RS09590 (PC0054_18660) comGD/cglD 1847983..1848417 (-) 435 WP_000608686.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8625_RS09595 (PC0054_18670) comGC/cglC 1848380..1848643 (-) 264 WP_000962025.1 competence type IV pilus major pilin ComGC Machinery gene
  R8625_RS09600 (PC0054_18680) - 1848645..1848902 (-) 258 WP_000698511.1 hypothetical protein -
  R8625_RS09605 (PC0054_18690) - 1849173..1850129 (-) 957 WP_219601358.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R8625_RS09610 (PC0054_18700) - 1850133..1850465 (-) 333 WP_050085269.1 phage holin -
  R8625_RS09615 (PC0054_18710) - 1850469..1850768 (-) 300 WP_001811580.1 hypothetical protein -
  R8625_RS09620 (PC0054_18720) - 1850777..1851127 (-) 351 WP_000852245.1 hypothetical protein -
  R8625_RS09625 (PC0054_18730) - 1851130..1851333 (-) 204 WP_001091109.1 hypothetical protein -
  R8625_RS09630 - 1851314..1851430 (-) 117 WP_001063633.1 hypothetical protein -

Sequence


Protein


Download         Length: 100 a.a.        Molecular weight: 11140.14 Da        Isoelectric Point: 9.7273

>NTDB_id=98218 R8625_RS09585 WP_317649158.1 1847718..1848020(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700054]
MEKLNALRKQKIRAMILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=98218 R8625_RS09585 WP_317649158.1 1847718..1848020(-) (comGE/cglE) [Streptococcus pneumoniae strain PZ900700054]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAATGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99

  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99

  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99

  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99

  comGE/cglE Streptococcus mitis NCTC 12261

97

100

0.97

  comGE/cglE Streptococcus mitis SK321

97

100

0.97

  comYE Streptococcus mutans UA140

44.444

90

0.4

  comYE Streptococcus mutans UA159

44.444

90

0.4


Multiple sequence alignment