Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8586_RS11205 Genome accession   NZ_AP026922
Coordinates   2135767..2136429 (-) Length   220 a.a.
NCBI ID   WP_000649965.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2130767..2141429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS11180 (PC0038_21850) - 2130917..2131183 (-) 267 WP_001278167.1 Veg family protein -
  R8586_RS11185 (PC0038_21860) dnaB 2131185..2132537 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8586_RS11190 (PC0038_21870) rplI 2132581..2133033 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8586_RS11195 (PC0038_21880) - 2133030..2135003 (-) 1974 WP_000715107.1 DHH family phosphoesterase -
  R8586_RS11200 (PC0038_21890) hpf 2135139..2135687 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8586_RS11205 (PC0038_21900) comFC/cflB 2135767..2136429 (-) 663 WP_000649965.1 ComF family protein Machinery gene
  R8586_RS11210 (PC0038_21910) comFA/cflA 2136426..2137724 (-) 1299 WP_000867610.1 DEAD/DEAH box helicase Machinery gene
  R8586_RS11215 (PC0038_21920) - 2137780..2138415 (+) 636 WP_000395740.1 YigZ family protein -
  R8586_RS11220 (PC0038_21930) cysK 2138700..2139620 (+) 921 WP_000029860.1 cysteine synthase A -
  R8586_RS11225 - 2139695..2140233 (-) 539 Protein_2172 transposase -
  R8586_RS11230 (PC0038_21950) - 2140206..2140493 (+) 288 Protein_2173 transposase -
  R8586_RS11235 (PC0038_21960) tnpB 2140629..2140862 (-) 234 WP_000376908.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25231.11 Da        Isoelectric Point: 7.7116

>NTDB_id=98154 R8586_RS11205 WP_000649965.1 2135767..2136429(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700038]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=98154 R8586_RS11205 WP_000649965.1 2135767..2136429(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700038]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGCTTGTCAATTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae Rx1

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae D39

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae R6

98.636

100

0.986
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909

Multiple sequence alignment