Detailed information    

insolico Bioinformatically predicted

Overview

Name   tfoX   Type   Regulator
Locus tag   AAFX12_RS08995 Genome accession   NZ_CP151938
Coordinates   1952364..1952951 (-) Length   195 a.a.
NCBI ID   WP_005378007.1    Uniprot ID   A0A2I3BZD4
Organism   Vibrio alginolyticus strain TBV025     
Function   master regulator of natural competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 1947364..1957951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFX12_RS08975 (AAFX12_09005) - 1947441..1948709 (-) 1269 WP_064368075.1 DUF945 family protein -
  AAFX12_RS08980 (AAFX12_09010) - 1948896..1950836 (+) 1941 WP_064369085.1 ATP-binding protein -
  AAFX12_RS08985 (AAFX12_09015) - 1950833..1951330 (+) 498 WP_005378005.1 response regulator -
  AAFX12_RS08990 (AAFX12_09020) - 1951622..1952170 (+) 549 WP_005378006.1 hypothetical protein -
  AAFX12_RS08995 (AAFX12_09025) tfoX 1952364..1952951 (-) 588 WP_005378007.1 TfoX/Sxy family DNA transformation protein Regulator
  AAFX12_RS09000 (AAFX12_09030) - 1953321..1954241 (+) 921 WP_005378009.1 HDOD domain-containing protein -
  AAFX12_RS09005 (AAFX12_09035) - 1954388..1955293 (+) 906 WP_005378011.1 lysine exporter LysO family protein -
  AAFX12_RS09010 (AAFX12_09040) - 1955502..1956014 (+) 513 WP_017634875.1 hypothetical protein -
  AAFX12_RS09015 (AAFX12_09045) panP 1956226..1957872 (+) 1647 WP_005378019.1 pyridoxal-dependent aspartate 1-decarboxylase PanP -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22412.73 Da        Isoelectric Point: 8.0901

>NTDB_id=981364 AAFX12_RS08995 WP_005378007.1 1952364..1952951(-) (tfoX) [Vibrio alginolyticus strain TBV025]
MDMTDQAFFKYVRTFSEYQKRSMFGGIGLFTDDAMFALVSNDCCYLRGGNGLDEVFTQLSCEKYKHVKKQTTATVNYYDV
TDLFESGYVGLDELVQKSIEYSIKERKYQKSSASRRLRDLPNMQLTLERMVKKAGVDDVETFLELGPVKVFNKVKTAYGN
DVDVKLLWKFAGATDGVHWKLIQEPRKKQLLALCD

Nucleotide


Download         Length: 588 bp        

>NTDB_id=981364 AAFX12_RS08995 WP_005378007.1 1952364..1952951(-) (tfoX) [Vibrio alginolyticus strain TBV025]
ATGGACATGACAGACCAAGCTTTTTTTAAATATGTACGCACCTTCAGTGAGTACCAAAAACGTTCTATGTTCGGTGGTAT
TGGTTTATTCACCGATGATGCTATGTTTGCGCTTGTCAGCAATGATTGCTGCTACTTACGTGGTGGTAATGGGCTAGATG
AAGTGTTTACTCAACTGAGCTGTGAGAAGTATAAGCACGTCAAAAAACAGACGACGGCAACCGTAAATTATTATGATGTA
ACCGATTTATTCGAATCCGGATATGTAGGGCTTGATGAACTGGTACAGAAATCAATTGAATACTCAATTAAGGAACGGAA
ATATCAAAAGTCCTCTGCCAGTAGACGCTTAAGAGACTTACCCAACATGCAACTAACCCTTGAACGTATGGTCAAGAAAG
CCGGTGTTGATGACGTAGAAACCTTTTTAGAACTTGGACCTGTAAAAGTCTTCAACAAAGTTAAAACGGCTTACGGTAAT
GATGTTGATGTAAAGCTACTGTGGAAATTTGCTGGTGCAACTGATGGCGTACATTGGAAACTGATCCAAGAGCCGCGTAA
AAAACAGTTATTGGCACTGTGTGACTAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(11-100)

TfoX C-terminal domain (TfoX_C)

(114-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I3BZD4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  tfoX Vibrio parahaemolyticus RIMD 2210633

89.744

100

0.897
  tfoX Vibrio campbellii strain DS40M4

87.692

100

0.877
  tfoX Vibrio cholerae O1 biovar El Tor str. N16961

66.667

98.462

0.656
  tfoX Vibrio cholerae O1 biovar El Tor strain DRC-193A

66.667

98.462

0.656
  tfoX Vibrio cholerae O1 biovar El Tor strain P27459

66.667

98.462

0.656
  tfoX Vibrio cholerae O1 biovar El Tor strain E7946

66.667

98.462

0.656
  tfoX Vibrio cholerae strain A1552

66.667

98.462

0.656
  tfoX Aliivibrio fischeri ES114

59.686

97.949

0.585

Multiple sequence alignment