Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ABXG87_RS00340 Genome accession   NZ_AP031488
Coordinates   57637..59580 (+) Length   647 a.a.
NCBI ID   WP_353551629.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NBRC 13956     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 52637..64580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXG87_RS00310 (Ssa13956_00400) argR 52842..53270 (+) 429 WP_170314548.1 arginine repressor -
  ABXG87_RS00315 (Ssa13956_00410) - 53270..53629 (+) 360 WP_084871095.1 YlbF family regulator -
  ABXG87_RS00320 (Ssa13956_00420) hexA 53622..56180 (+) 2559 WP_155164784.1 DNA mismatch repair protein MutS Machinery gene
  ABXG87_RS00325 (Ssa13956_00430) - 56214..56669 (-) 456 WP_353551627.1 DUF3021 domain-containing protein -
  ABXG87_RS00330 (Ssa13956_00440) - 56666..57103 (-) 438 WP_045772361.1 LytTR family DNA-binding domain-containing protein -
  ABXG87_RS00335 - 57282..57587 (+) 306 WP_002886319.1 hypothetical protein -
  ABXG87_RS00340 (Ssa13956_00450) hexB 57637..59580 (+) 1944 WP_353551629.1 DNA mismatch repair endonuclease MutL Machinery gene
  ABXG87_RS00345 (Ssa13956_00460) - 59711..59932 (+) 222 WP_002886321.1 hypothetical protein -
  ABXG87_RS00350 (Ssa13956_00470) ruvA 60090..60680 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  ABXG87_RS00355 (Ssa13956_00480) - 60689..61243 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  ABXG87_RS00360 (Ssa13956_00490) cinA 61340..62608 (+) 1269 WP_353551631.1 competence/damage-inducible protein A Machinery gene
  ABXG87_RS00365 (Ssa13956_00500) recA 62644..63783 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  ABXG87_RS00370 (Ssa13956_00510) spx 63950..64348 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72519.56 Da        Isoelectric Point: 5.2049

>NTDB_id=98043 ABXG87_RS00340 WP_353551629.1 57637..59580(+) (hexB) [Streptococcus salivarius strain NBRC 13956]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTATDGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESESPVSSVENKS
QPSVKQAQRSVDEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=98043 ABXG87_RS00340 WP_353551629.1 57637..59580(+) (hexB) [Streptococcus salivarius strain NBRC 13956]
ATGCCAAAAATCATCGAATTGCCAGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGTCCAGCTAGTGT
TGTCAAAGAGTTGGTGGAAAATGCTATTGATGCTGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGTGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAACGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAAAGTTTACAGGCTGAGTTGGCCCATATTGTTGATGTTGTCAATCGTCTGAGTCTAGCACATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCTAACCGTAATTACATCACGATTCTCATTAACGGACGTTATATCAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAAATTGATCCCTACT
TGGCTGATGTCAATGTTCACCCAACCAAGCAGGAAGTACGTATTTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTGTATCAGAGTCAGAGTCTCCAGTTTCATCGGTAGAAAATAAATCG
CAACCTTCTGTTAAACAGGCACAACGTTCAGTAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAACTCTGGATAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGTGGACTTTACATCATTGACCAACATGCTGCTCAAGAACGTGTCAAGTAT
GAGTACTATCGTGAAAAGATCGGTGAGGTTGACAGCAGTTTACAACAGCTCTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCAGATTACATCAGTTTACAAGAAAAAATGCCCCTTCTGAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAATA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCAGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
TAATCATGCACTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACGAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(448-591)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.605

100

0.708

Multiple sequence alignment