Detailed information NTG0098043

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: R9C51_RS08815
• Genome accession: NZ_AP026921
• Coordinates: 1718198..1718857 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565605.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700027
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1713198..1723857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R9C51_RS08780 (PC0027_17440)	mgaSpn	1713809..1715290 (-)	1482	WP_001205283.1	virulence factor transcriptional regulator MgaSpn	-
R9C51_RS08785 (PC0027_17450)	-	1715733..1715897 (+)	165	WP_001820780.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
R9C51_RS08790	amaP	1715981..1716547 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
R9C51_RS08795 (PC0027_17470)	-	1716559..1716729 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
R9C51_RS08800 (PC0027_17480)	-	1716768..1717376 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
R9C51_RS08805 (PC0027_17490)	-	1717407..1717610 (+)	204	WP_000109961.1	CsbD family protein	-
R9C51_RS08810 (PC0027_17500)	-	1717682..1718128 (-)	447	WP_000155416.1	GNAT family N-acetyltransferase	-
R9C51_RS08815 (PC0027_17510)	cclA/cilC	1718198..1718857 (+)	660	WP_000565605.1	A24 family peptidase	Machinery gene
R9C51_RS08820 (PC0027_17520)	-	1718909..1720060 (-)	1152	WP_000481750.1	ImmA/IrrE family metallo-endopeptidase	-
R9C51_RS08825 (PC0027_17530)	-	1720075..1720749 (-)	675	WP_000678278.1	hypothetical protein	-
R9C51_RS08830	-	1721025..1721135 (+)	111	Protein_1753	prepilin peptidase	-
R9C51_RS08835 (PC0027_17540)	trpA	1721107..1721883 (-)	777	WP_001127043.1	tryptophan synthase subunit alpha	-
R9C51_RS08840 (PC0027_17550)	trpB	1721876..1723099 (-)	1224	WP_000331295.1	tryptophan synthase subunit beta	-
R9C51_RS08845 (PC0027_17560)	-	1723077..1723676 (-)	600	WP_000169907.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24793.89 Da
• Isoelectric Point: 7.6166

>NTDB_id=98043 R9C51_RS08815 WP_000565605.1 1718198..1718857(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700027]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=98043 R9C51_RS08815 WP_000565605.1 1718198..1718857(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700027]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae D39	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae R6	95.89	100	0.959
cclA/cilC	Streptococcus mitis SK321	93.151	100	0.932
cclA/cilC	Streptococcus mitis NCTC 12261	87.671	100	0.877