Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8566_RS11290 Genome accession   NZ_AP026920
Coordinates   2176871..2177533 (-) Length   220 a.a.
NCBI ID   WP_000649978.1    Uniprot ID   A0A0E8ARN2
Organism   Streptococcus pneumoniae strain PZ900700014     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2171871..2182533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8566_RS11265 (PC0014_22040) - 2172021..2172287 (-) 267 WP_001278167.1 Veg family protein -
  R8566_RS11270 (PC0014_22050) dnaB 2172289..2173641 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8566_RS11275 (PC0014_22060) rplI 2173685..2174137 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8566_RS11280 (PC0014_22070) - 2174134..2176107 (-) 1974 WP_000715109.1 DHH family phosphoesterase -
  R8566_RS11285 (PC0014_22080) hpf 2176243..2176791 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8566_RS11290 (PC0014_22090) comFC/cflB 2176871..2177533 (-) 663 WP_000649978.1 ComF family protein Machinery gene
  R8566_RS11295 (PC0014_22100) comFA/cflA 2177530..2178828 (-) 1299 WP_000867601.1 DEAD/DEAH box helicase Machinery gene
  R8566_RS11300 (PC0014_22110) - 2178884..2179519 (+) 636 WP_000395739.1 YigZ family protein -
  R8566_RS11305 (PC0014_22120) cysK 2179804..2180730 (+) 927 WP_000029873.1 cysteine synthase A -
  R8566_RS11310 (PC0014_22130) tsf 2180851..2181891 (-) 1041 WP_000808063.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25240.11 Da        Isoelectric Point: 7.7116

>NTDB_id=97996 R8566_RS11290 WP_000649978.1 2176871..2177533(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700014]
MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=97996 R8566_RS11290 WP_000649978.1 2176871..2177533(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700014]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATAATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCTTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E8ARN2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment