Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8613_RS11060 Genome accession   NZ_AP026919
Coordinates   2115073..2115735 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2110073..2120735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS11035 (PC0012_21150) - 2110224..2110490 (-) 267 WP_001278167.1 Veg family protein -
  R8613_RS11040 (PC0012_21160) dnaB 2110492..2111844 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8613_RS11045 (PC0012_21170) rplI 2111887..2112339 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8613_RS11050 (PC0012_21180) - 2112336..2114309 (-) 1974 WP_000715109.1 DHH family phosphoesterase -
  R8613_RS11055 (PC0012_21190) hpf 2114445..2114993 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8613_RS11060 (PC0012_21200) comFC/cflB 2115073..2115735 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  R8613_RS11065 (PC0012_21210) comFA/cflA 2115732..2117030 (-) 1299 WP_317648301.1 DEAD/DEAH box helicase Machinery gene
  R8613_RS11070 (PC0012_21220) - 2117086..2117721 (+) 636 WP_317648302.1 YigZ family protein -
  R8613_RS11075 (PC0012_21230) cysK 2118006..2118926 (+) 921 WP_000029866.1 cysteine synthase A -
  R8613_RS11080 - 2119001..2119539 (-) 539 Protein_2154 transposase -
  R8613_RS11085 (PC0012_21250) - 2119512..2119799 (+) 288 Protein_2155 transposase -
  R8613_RS11090 (PC0012_21260) tnpB 2119972..2120259 (-) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=97918 R8613_RS11060 WP_000649971.1 2115073..2115735(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700012]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=97918 R8613_RS11060 WP_000649971.1 2115073..2115735(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700012]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGCTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment