Detailed information NTG0097868

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8613_RS04850
• Genome accession: NZ_AP026919
• Coordinates: 930790..931743 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain PZ900700012
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 925790..936743

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8613_RS04825	rpmG	926533..926682 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R8613_RS04830 (PC0012_09320)	secG	926722..926955 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8613_RS04835 (PC0012_09330)	rnr	927057..929411 (+)	2355	WP_000654886.1	ribonuclease R	-
R8613_RS04840 (PC0012_09340)	smpB	929374..929841 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8613_RS04845 (PC0012_09350)	tehB	929857..930717 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R8613_RS04850 (PC0012_09360)	coiA	930790..931743 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R8613_RS04855 (PC0012_09370)	pepF	931762..933573 (+)	1812	WP_050204886.1	oligoendopeptidase F	Regulator
R8613_RS04860 (PC0012_09380)	-	933575..934288 (+)	714	WP_000230399.1	O-methyltransferase	-
R8613_RS04865 (PC0012_09390)	prsA	934355..935296 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R8613_RS04870 (PC0012_09400)	-	935413..935754 (-)	342	Protein_966	transposase	-
R8613_RS04875	-	936167..936262 (+)	96	Protein_967	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=97868 R8613_RS04850 WP_000495909.1 930790..931743(+) (coiA) [Streptococcus pneumoniae strain PZ900700012]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=97868 R8613_RS04850 WP_000495909.1 930790..931743(+) (coiA) [Streptococcus pneumoniae strain PZ900700012]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435